Related ArticlesA National Consensus Survey for Current Practice in Brain Tumor Management I: Antiepileptic Drug and Steroid Usage. Brain Tumor Res Treat. 2020 Apr;8(1):1-10 Authors: Kim SK, Moon J, Cho JM, Kim KH, Kim SH, Kim YI, Kim YZ, Kim HS, Dho YS, Park JS, Park JE, Seo Y, Sung KS, Song JH, Wee CW, Yoon WS, Yoon HI, Lee SH, Lim DH, Im JH, Chang JH, Han MH, Hong JB, Hwang K, Park CK, Lee YS, Gwak HS, KSNO Guideline Working Group Abstract BACKGROUND:...
Wed May 13, 2020 08:35
Related ArticlesPrecise Pulmonary Function Evaluation and Management of a Patient With Freeman-Sheldon Syndrome Associated With Recurrent Pneumonia and Chronic Respiratory Insufficiency. Ann Rehabil Med. 2020 Apr;44(2):165-170 Authors: Park J, Kang SW, Choi WA, Lee Y, Cho HE Abstract Freeman-Sheldon syndrome (FSS) is a rare distal arthrogryposis syndrome. There are few reports on the respiratory insufficiency of FSS. Additionally, there is no detailed...
Wed May 13, 2020 08:10
Related ArticlesA Bibliometric Analysis Using Alternative Metrics for Articles in the Annals of Rehabilitation Medicine. Ann Rehabil Med. 2020 Apr;44(2):158-164 Authors: Han SC, Kang HJ, Lee WJ, Chung HS, Lee JH Abstract OBJECTIVE: To investigate the articles in the Annals of Rehabilitation Medicine (ARM) using a bibliometric analysis to verify whether there is a correlation between the topics of interest for expert groups and the public media. ...
Wed May 13, 2020 08:10
Related ArticlesFrequency of and Reasons for Unplanned Transfers From the Inpatient Rehabilitation Facility in a Tertiary Hospital. Ann Rehabil Med. 2020 Apr;44(2):151-157 Authors: Im S, Lim DY, Sohn MK, Kim Y Abstract OBJECTIVE: To characterize the patients in the inpatient rehabilitation facility who were transferred to acute care facilities and identify the frequency of and reasons for the unplanned transfer. METHODS: Medical records of...
Wed May 13, 2020 08:10
Related ArticlesInfluence of RehaCom Therapy on the Improvement of Manual Skills in Multiple Sclerosis Subjects. Ann Rehabil Med. 2020 Apr;44(2):142-150 Authors: Pawlukowska W, Dobrowolska N, Szylinska A, Koziarska D, Meller A, Rotter I, Nowacki P Abstract OBJECTIVE: To assess the influence of cognitive therapy, in combination with cognitive software, on manual dexterity in individuals with multiple sclerosis (MS). METHODS: The Nine-Hole Peg...
Wed May 13, 2020 08:10
Related ArticlesEnergy Efficiency and Patient Satisfaction of Gait With Knee-Ankle-Foot Orthosis and Robot (ReWalk)-Assisted Gait in Patients With Spinal Cord Injury. Ann Rehabil Med. 2020 Apr;44(2):131-141 Authors: Kwon SH, Lee BS, Lee HJ, Kim EJ, Lee JA, Yang SP, Kim TY, Pak HR, Kim HK, Kim HY, Jung JH, Oh SW Abstract OBJECTIVE: To compare the energy efficiency of gait with knee-ankle-foot orthosis (KAFO) and robot-assisted gait and to develop a usability...
Wed May 13, 2020 08:10
Related ArticlesComparison of Two Static Stretching Techniques for the Triceps Surae in Healthy Individuals: Wall and Inclined Board Stretchings. Ann Rehabil Med. 2020 Apr;44(2):125-130 Authors: Kim TH, Lim OK, Park KD, Lee JK Abstract OBJECTIVE: To compare the effectiveness of static stretching techniques for correcting the tightness of the triceps surae. METHODS: In this observational, cross-sectional study, participants (30 healthy volunteers)...
Wed May 13, 2020 08:10
Related ArticlesChanges in Blood Glucose Level After Steroid Injection for Musculoskeletal Pain in Patients With Diabetes. Ann Rehabil Med. 2020 Apr;44(2):117-124 Authors: Shin WY, An MJ, Im NG, Oh KR, Choe Y, Yoon SR, Ryu SR Abstract OBJECTIVE: To investigate changes in blood glucose level after steroid injection in patients with type 2 diabetes mellitus (DM) and factors affecting those changes. METHODS: We retrospectively studied 51 patients...
Wed May 13, 2020 08:10
Related ArticlesFactors Affecting Compliance With Weight-Bearing Restriction and the Amount of Weight-Bearing in the Elderly With Femur or Pelvic Fractures. Ann Rehabil Med. 2020 Apr;44(2):109-116 Authors: Seo H, Lee GJ, Shon HC, Kong HH, Oh M, Cho H, Lee CJ Abstract OBJECTIVE: To determine the factors affecting the amount of weight-bearing during gait training in the elderly patients who underwent internal fixation after femur or pelvic fractures and...
Wed May 13, 2020 08:10
Related ArticlesDose-Response Effect of Daily Rehabilitation Time on Functional Gain in Stroke Patients. Ann Rehabil Med. 2020 Apr;44(2):101-108 Authors: Ko H, Kim H, Kim Y, Sohn MK, Jee S Abstract OBJECTIVE: To demonstrate the effect of daily treatment time on recovery of functional outcomes and how each type of rehabilitation treatment influences the improvement of subgroups of functional outcomes in stroke patients. METHODS: We conducted...
Wed May 13, 2020 08:10
Related ArticlesCOVID-19 Viral Load of an Infected Family in China. Clin Lab. 2020 May 01;66(5): Authors: Wang D, Song C, Zhou Y, Xu K, Zhou Z, Ge L, Zhang Y PMID: 32390405 [PubMed - in process]
Wed May 13, 2020 07:43
Related ArticlesIntegration of Liquid Biopsies into Clinical Laboratory Applications via NGS in Cancer Diagnostics. Clin Lab. 2020 May 01;66(5): Authors: Sonmezler O, Boga I, Bisgin A Abstract BACKGROUND: Next Generation Sequencing is one of the latest advances in molecular testing and clinical laboratory applications. Next Generation Sequencing techniques involving liquid biopsies are emerging as important tools in cancer diagnostics and prognostics....
Wed May 13, 2020 07:43
Related ArticlesMeasures to Avoid Exogenous RNA Contamination of NCP Nucleic Acid Detection. Clin Lab. 2020 May 01;66(5): Authors: Wang D, Song C, Ren T, Zhou Y, Zhou Z, Ge L, Zhang Y PMID: 32390403 [PubMed - in process]
Wed May 13, 2020 07:43
Related ArticlesSARS-CoV-2 and Eosinophilia. Clin Lab. 2020 May 01;66(5): Authors: Mungmunpuntipantip R, Wiwanitkit V PMID: 32390402 [PubMed - indexed for MEDLINE]
Wed May 13, 2020 07:43
Related ArticlesThe Role of Resolvin D1 in the Differential Diagnosis of the Cholangiocarcinoma and Benign Biliary Diseases. Clin Lab. 2020 May 01;66(5): Authors: Gül-Utku Ö, Karatay E, Ergül B, Kisa Ü, Erdin Z, Oğuz D Abstract BACKGROUND: The discrimination of malignant biliary strictures from benign biliary diseases (BBDs) is challenging and complicated. We aimed to investigate whether Resolvin D1 (RvD1) would aid in the discrimination of cholan-giocarcinoma...
Wed May 13, 2020 07:43
Related ArticlesIncreased Intact Proinsulin in the Oral Glucose Challenge Sample is an Early Indicator for Future Type 2 Diabetes Development - Case Reports and Evidence from the Literature. Clin Lab. 2020 May 01;66(5): Authors: Pfützner A, Manessis A, Hanna MR, Lewin J Abstract BACKGROUND: Increased intact proinsulin in plasma is a highly specific biomarker for a major disruption of insulin-processing in the pancreatic β-cells with associated insulin...
Wed May 13, 2020 07:43
Related ArticlesMean Platelet Volume in Patients with Increased Lipoprotein(a) Levels. Clin Lab. 2020 May 01;66(5): Authors: Jeon Y, Kim YJ, Cho SY PMID: 32390399 [PubMed - in process]
Wed May 13, 2020 07:43
Related ArticlesA 2-Year-Old Child with Late-Onset Pompe Disease: a Case Report. Clin Lab. 2020 May 01;66(5): Authors: Li S, Zhu C, Li P Abstract BACKGROUND: Pompe disease is an inherited neuromuscular disease caused by a deficiency of lysosomal acid alphaglucosidase (GAA) leading to glycogen accumulation in muscle and motor neurons. METHODS: We retrospectively collected the clinical information on the case of a 2-year-old child admitted to...
Wed May 13, 2020 07:43
Integrated Analysis of Long Non-Coding RNA and mRNA Expression Profile in Myelodysplastic Syndromes.
Related ArticlesIntegrated Analysis of Long Non-Coding RNA and mRNA Expression Profile in Myelodysplastic Syndromes. Clin Lab. 2020 May 01;66(5): Authors: Wen J, Luo Q, Wu Y, Zhu S, Miao Z Abstract BACKGROUND: Myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid malignancies. The incidence of MDS is gradually increasing, but the pathogenesis is still not very clear. Studies have shown that long non-coding RNAs (lncRNAs) play a critical...
Wed May 13, 2020 07:43
Related ArticlesPrevalence and Genotype Distribution of Human Papillomavirus From 9,182 Individuals Participated Health Examination. Clin Lab. 2020 May 01;66(5): Authors: Zhang C, Xie CB, Du Q, Hu HH, Liu XQ, Long J, Zhong JL, Jiang W Abstract BACKGROUND: Human papillomavirus (HPV) is the cause of nearly all cervical cancers and the primary cause of anal cancers. Prevalence of HPV varies largely among countries and regions, and population-based data...
Wed May 13, 2020 07:43
Related ArticlesLINE-1 Methylation in Chronic HBV Infected Patients: Association with HCC, Gender and MTHFR C677T Polymorphism. Clin Lab. 2020 May 01;66(5): Authors: Qiao K, Zhang S, Huo Z, Hou W, Dai Q, Su R, Wang F Abstract BACKGROUND: Polymorphism of methylene tetrahydrofolate reductase (MTHFR) C677T has been reported to be associated with HBV-related hepatocellular carcinoma (HCC) risk. However, the underlying mechanism remains elusive. DNA methylation...
Wed May 13, 2020 07:43
Related ArticlesCervical Cancer Associated Biomarkers of Identify High Risk of Venous Thrombosis. Clin Lab. 2020 May 01;66(5): Authors: Liang H, Guo X, Li Y Abstract BACKGROUND: Our study aims to assess the validity of thrombotic biomarkers in estimation of venous thrombosis risk in cervical cancer patients. METHODS: A total of 134 cervical cancer patients treated in our hospital from September 2016 to November 2017 were selected. Coagulation...
Wed May 13, 2020 07:43
Related ArticlesDiagnostic Value of Serum Long-Chain Noncoding RNA KCNQ1OT1 in Airway Remodeling in Children with Bronchial Asthma. Clin Lab. 2020 May 01;66(5): Authors: Gu C, Wang H, Yang S Abstract BACKGROUND: The current study aims to investigate the clinical value of serum long non-coding RNA (lncRNA) KCNQ1OT1 in airway remodeling in children with bronchial asthma. METHODS: Serum and clinical data of 58 children with bronchial asthma were...
Wed May 13, 2020 07:43
Related ArticlesThe Utility of Rise in Red Cell Distribution Width in Determining the Risk of Renal Relapse in Lupus Nephritis. Clin Lab. 2020 May 01;66(5): Authors: You H, Wang T, Liu S, Zhu X, Lu J, Zhu Y, Xue J, Hao C Abstract BACKGROUND: We hypothesized that the levels of red cell distribution width (RDW) would correlate with lupus nephritis (LN) disease activity, therapeutic response after induction therapy, and its rise would be associated with...
Wed May 13, 2020 07:43
Related ArticlesContrasting Results from Two Commercial Kits Testing for the Presence of Clostridium perfringens Enterotoxin in Feces from Norovirus-Infected Human Patients. Clin Lab. 2020 May 01;66(5): Authors: Ishioka T, Aihara Y, Carle Y, Shigemura H, Kubomura A, Motoya T, Nakamoto A, Nakamura A, Fujimoto S, Hirai S, Oishi K, Nagaoka H, Kimura H, Murakami K Abstract BACKGROUND: Detection of Clostridium perfringens enterotoxin (CPE) is critical for...
Wed May 13, 2020 07:43
Related ArticlesMolecular Detection and Characterization of Picobirnavirus in Environmental Water in Thailand. Clin Lab. 2020 May 01;66(5): Authors: Bell N, Khamrin P, Kumthip K, Rojjanadumrongkul K, Nantachit N, Maneekarn N Abstract BACKGROUND: Enteric viruses are responsible for waterborne and foodborne infections affecting a large number of people around the world. Picobirnavirus (PBV) is a highly versatile virus, detected in a wide range of hosts...
Wed May 13, 2020 07:43
Related ArticlesGhrelin Levels and Hunger Sensation after Laparoscopic Sleeve Gastrectomy Compared with Laparoscopic Greater Curvature Plication in Obese Patients. Clin Lab. 2020 May 01;66(5): Authors: Dobrescu A, Copaescu C, Zmeu B, Duta C, Bedreag OH, Stoica L, Tarta C, Rogobete AF, Lazar F Abstract BACKGROUND: The aims of our study were to compare serum acylated ghrelin (the active form of ghrelin) concentrations before and after the surgery of patients...
Wed May 13, 2020 07:43
Related ArticlesPlasma miR-513a-5p as a Potential Biomarker for Diagnosis of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Mellitus Patients. Clin Lab. 2020 May 01;66(5): Authors: Li F, Wu X, Zhang Y, Wei K Abstract BACKGROUND: The current study aims to investigate the relationship between plasma levels of miR-513a-5p and lipid metabolism and insulin resistance in patients with type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease...
Wed May 13, 2020 07:43
Related ArticlesA Potential Serum Biomarker, Albumin-to-Glutamyltransferase Ratio, Suggests the Severity of Liver Disease. Clin Lab. 2020 May 01;66(5): Authors: Pan N, Liu J, Deng H, Zheng W, Cui S, Wei W, Lan X, Yu H, Wang J, Xiao L Abstract BACKGROUND: We aimed to investigate the utility of albumin-to-glutamyltransferase ratio (AGR) as a new biomarker to distinguish hepatic carcinoma from hepatitis, as early disease diagnosis, prognosis or monitoring...
Wed May 13, 2020 07:43
Related ArticlesLipoprotein-Associated Phospholipase A2 in Cardiac Disease: a Potential Early Biomarker of Unstable Coronary Artery Disease. Clin Lab. 2020 May 01;66(5): Authors: Li J, Zhou Z, Niu X, Li H Abstract BACKGROUND: Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a serine lipase that deteriorates the stability of atherosclerotic plaques. This study aims to investigate Lp-PLA2 activity and its diagnostic potential in the early period of...
Wed May 13, 2020 07:43
Related ArticlesSerum Procalcitonin, White Blood Cell and Hypersensitive C-reactive Protein Combined with Age Established a New Prediction Model in Predicting ICU Admission in Adult Community-Acquired Pneumonia (CAP) Patients. Clin Lab. 2020 May 01;66(5): Authors: Li WQ, Chen Y, Liu TJ, Xie BQ, Fu AS, Li LQ, Ge YL, Min P, Lu Y, Liu Y, Sun Y, Hou LL, Jing Q, Zhang HF, Zhang JB Abstract BACKGROUND: CAP is the most common cause of death in infectious diseases...
Wed May 13, 2020 07:43
Related ArticlesAberrant Methylation of Suppressor of Cytokine Signaling 1 (SOCS1) Gene as a Biomarker for Early Prediction and Diagnosis of Bladder Cancer. Clin Lab. 2020 May 01;66(5): Authors: Guan H, Li X, Lu J, Meng L, Guo Y, Dong J, Rong S, Zhao F, Shen H Abstract BACKGROUND: SOCS1 protein, the negative regulatory protein of the Janus kinase (JAK)/signal transducers and activators of transcription (STAT) signaling pathway, may inhibit signaling...
Wed May 13, 2020 07:43
Related ArticlesCirculating C-Reactive Protein to Prealbumin Ratio and Prealbumin to Fibrinogen Ratio are Two Promising Inflammatory Markers Associated with Disease Activity in Rheumatoid Arthritis. Clin Lab. 2020 May 01;66(5): Authors: Wang J, Xi H, Zhang K, Li Z, Li L, Chen J, Lou Z Abstract BACKGROUND: The C-reactive protein to prealbumin ratio (CPR) and prealbumin to fibrinogen ratio (PFR) are two new inflammatory markers that were reported to have...
Wed May 13, 2020 07:43
Related ArticlesPrognostic Significance of Matrix Metalloproteinase 14 in Patients with Cancer: a Systematic Review and Meta-Analysis. Clin Lab. 2020 May 01;66(5): Authors: Zhang L, Jin S, Wei Y, Wang C, Zou H, Hu J, Jia W, Pang L Abstract BACKGROUND: There is increasing evidence that matrix metalloproteinase 14 (MMP-14) is involved in tumor progression and prognosis. MMP-14 exhibits different expression in patients with various cancers, suggesting...
Wed May 13, 2020 07:43
Related ArticlesCharacterization of Chlamydia trachomatis ompA Genotypes Among Sexually Transmitted Disease Patients in Korea. Clin Lab. 2020 May 01;66(5): Authors: Chung Y, Han M, Park JY, Kim I, Kim JS Abstract BACKGROUND: Chlamydia trachomatis is the leading cause of bacterial sexually transmitted diseases (STDs) world-wide. The aim of this study was to characterize the C. trachomatis genetic profiles of clinical isolates in the Korean population...
Wed May 13, 2020 07:43
Related ArticlesEffect of Lead Exposure on Spontaneous Abortion: a Case-Control Study. Clin Lab. 2020 May 01;66(5): Authors: Ou J, Peng P, Qiu L, Teng L, Li C, Han J, Liu X Abstract BACKGROUND: The aim of the study is to determine the effects of blood lead levels (BLLs) on spontaneous abortion. METHODS: A well-matched case-control study was performed at Peking Union Medical College Hospital from 2016 - 2018. Spontaneous abortion cases requiring...
Wed May 13, 2020 07:43
Related ArticlesThe Diagnostic Value of Antibodies Against Citrullinated or Carbamylated Fibrinogen in Rheumatoid Arthritis. Clin Lab. 2020 May 01;66(5): Authors: Wang Z, Xue L, Xie J, Zhu N Abstract BACKGROUND: This study aimed to evaluate the overall diagnostic value of citrullinated or carbamylated fibrinogen antibodies in patients with rheumatoid arthritis (RA). METHODS: Serum samples collected from 114 patients with established RA, 143...
Wed May 13, 2020 07:43
Related ArticlesPlasma Levels and Gene Expression of RANK in Non-Alcoholic Fatty Liver Disease. Clin Lab. 2020 May 01;66(5): Authors: Hadinia A, Doustimotlagh AH, Goodarzi HR, Arya A, Jafarinia M Abstract BACKGROUND: The pathobiology of initiation and progression of nonalcoholic fatty liver disease (NAFLD) has not been completely elucidated. It seems that the RANK/RANKL/OPG cytokine system play an etiologic role in pathogenesis of this disease. This...
Wed May 13, 2020 07:43
Related ArticlesHigh Sensitivity Detection of Anti-DFS70 Antibodies by Radioimmunoprecipitation Assay (RIPA). Clin Lab. 2020 May 01;66(5): Authors: Seelig CA, Blüthner M, Seelig HP Abstract BACKGROUND: Autoantibodies against the chromosome associated protein DFS70/LEDGF (dense fine speckled 70/ lens epithelial growth factor; anti-DSF70) are increasingly being regarded as biomarkers for the diagnostic exclusion of systemic autoimmune rheumatic diseases...
Wed May 13, 2020 07:43
Related ArticlesSerum Prealbumin Improves the Sensitivity of Pneumonia Severity Index in Predicting 30-day Mortality of CAP Patients. Clin Lab. 2020 May 01;66(5): Authors: Zhang HF, Li LQ, Ge YL, Zhang JB, Fu AS, Liu CH, Shao DF, Bai J, Zhu XY Abstract BACKGROUND: Serum prealbumin (PAB) is an effective tool to evaluate patients with malnutrition. In recent years, studies have shown that PAB is statistically reduced during the course of disease infection....
Wed May 13, 2020 07:43
Related ArticlesThe Prevalence of Periodontal Pathogenic Bacteria in Atherosclerotic Cardiovascular Disease. Clin Lab. 2020 May 01;66(5): Authors: Gode S, Sarp TZ, Saribas S, Ergin S, Kasnak G, Dinc HO, Caliskan R, Akkus S, Tokman HB, Kocak BT, Demirci M, Gareayaghi N, Kirmusaoglu S, Tokman H, Kocazeybek B Abstract BACKGROUND: A possible link between periodontal pathogenic bacteria and atherosclerosis may exist based on the inflammatory mechanisms initiated...
Wed May 13, 2020 07:43
Related ArticlesMatrix Metalloproteases and Cathepsin D in Human Serum do not Cleave Prolactin to Generate Vasoinhibin. Clin Lab. 2020 May 01;66(5): Authors: Triebel J, Schauer N, Zamora M, Moreno-Vega AI, Escalera GM, Clapp C, Bertsch T Abstract BACKGROUND: Vasoinhibin is generated in the pituitary gland and in multiple target tissues by proteolytic cleavage of prolactin by matrix metalloproteinases and cathepsin D. A dysregulation of vasoinhibin generation...
Wed May 13, 2020 07:43
Objective: To assess the efficacy of cochlear implantation (CI) after surgical removal of sporadic intracochlear or intravestibulocochlear schwannomas. Study Design: Nonconcurrent cohort study. Setting: Monocentric study at a tertiary referral center. Patients: Patients with tumor resection and CI between 2011 and 2018 and a historic control group of CI patients matched by age, CI electrode type, and follow-up. Interventions: Partial or subtotal cochleoectomy for tumor removal...
Wed May 13, 2020 07:38
No abstract available
Wed May 13, 2020 07:38
Objective: To assess the influence of congenital and permanent unilateral hearing loss (UHL) on early prelingual auditory development (EPLAD) of infants and toddlers. Study Design: A cross-sectional and case-controlled design. Setting: Tertiary referral center. Patients: Sixty-five young children (median with interquartile ranges: 4.4 [3.3, 7.7] mo) with UHL, 70 children (6.0 [3.8, 9.0] mo) with bilateral normal hearing (BNH) and 32 children (5.8 [3.9, 12.1] mo) with bilateral mild...
Wed May 13, 2020 07:38
No abstract available
Wed May 13, 2020 07:38
Objective: This study aimed to determine whether there is an association between osteopenia and residual dizziness after successful treatment of benign paroxysmal positional vertigo (BPPV). Methods: In all, 62 patients with canalolithiasis-type BPPV were included in the study. Patients were divided into two groups according to the presence of residual dizziness after resolution of BPPV. Univariate and multivariate analyses were performed to determine the factors associated with residual dizziness....
Wed May 13, 2020 07:38
Introduction: Developments in bone-anchored hearing implants have resulted in fewer complications, and, thus, lower complication-related costs. However, a weighing of the potential clinical benefits with higher implant purchase price is lacking. Methods: A mathematical Markov model was used to evaluate the total costs (complication costs, implant purchase price, and standard costs) of three widely used current generation implants with expected similar outcomes, compared to a previous generation...
Wed May 13, 2020 07:38
Objectives: To understand the growth rate of mastoid thickness and skull width associated with the age for both normal and malformed inner-ear anatomy groups. Also, to determine if there is any mathematical relation between cochlear size as measured by the “A” value against the age, mastoid thickness, and skull width. Methods: Ninety-two computed tomography image datasets of human temporal bone were made available that contained normal (n = 44) and malformed inner-ear (n = 48) anatomies....
Wed May 13, 2020 07:38
Introduction: Three-dimensional (3D) tools have played a significant role in advancing anatomical knowledge, in simulation and clinical practice in Otology. Technology is evolving at a rapid rate with new applications being reported at an overwhelming pace. It is important to continuously review new applications, assess emerging trends, and identify challenges to innovation so clinical translation progresses in an efficient and evidenced-based manner. Methods: A review of 20 years of literature...
Wed May 13, 2020 07:38
Objectives: To investigate false-positive findings on non-echoplanar (non-EPI) diffusion-weighted magnetic resonance imaging (DWI) in patients under surveillance post-cholesteatoma surgery. Study Design, Setting, Subjects, and Methods: A retrospective review was performed on patients diagnosed with cholesteatoma who underwent surgical resection and were then followed by serial non-EPI DWI using half-Fourier acquisition single-shot turbo spin echo (HASTE) sequence. All patients had at least...
Wed May 13, 2020 07:38
Objectives: In this review, we discuss current knowledge about the genetics and epigenetics of vestibular schwannoma (VS) in relation to hearing loss. A multistep and sequential genetic algorithm suitable for the identification of Neurofibromatosis Type 2 (NF2) constitutional and somatic mutations is discussed. Data Sources, Study Selection: A review was performed of the English literature from 1990 to 2019 using PubMed regarding genetics and epigenetics of vestibular schwannoma and NF2. ...
Wed May 13, 2020 07:38
Objective: Evaluate whether the difference between word recognition score (WRS) obtained unaided under earphone and with a hearing aid (HA), the speech perception gap (SPgap), is predictive of performance with a totally implantable active middle ear implant (AMEI). Study Design: Retrospective review of systematically collected data. Setting: Private otologic practice. Patients: One hundred thirty six ears (133 patients) with sensorineural hearing loss implanted with an AMEI. Subjects...
Wed May 13, 2020 07:38
Objectives: The rise in the use of cochlear implants (CIs) has continued to fuel research aimed at improving surgical approaches and the preservation of residual hearing. Current in vivo models involve small animals not suitable for evaluating full-sized CIs nor are prohibitively expensive nonhuman primates. The objective of this study was to develop and evaluate an in vivo model of cochlear implantation in sheep. Methods: Eight adult, female sheep were implanted with full-sized CIs from...
Wed May 13, 2020 07:38
Objective: To determine short- and intermediate-term hearing preservation rates after microsurgical resection of vestibular schwannoma (VS). Data Sources: Systematic review of the Ovid, Cochrane, EMBASE, and Web of Science databases. Study Selection: This study was restricted to full-text English-language articles detailing VS resection via the middle cranial fossa or retrosigmoid approaches. Documentation of pre- and posttreatment hearing outcomes with American Academy of Otolaryngology–Head...
Wed May 13, 2020 07:38
Objective: To present surgical and audiometric outcomes of patients implanted with an active transcutaneous bone conduction implant following the novel middle fossa surgical approach with self-drilling screws. Study Design: Retrospective review. Setting: Tertiary care center. Patients: Thirty-seven adults with either conductive or mixed hearing loss that met indications for an active transcutaneous bone conduction implant were consecutively implanted from April, 2013 to May, 2018. ...
Wed May 13, 2020 07:38
Objective: No previous studies have investigated a vestibular function test battery combining the Video Head Impulse Test (VHIT), the caloric test, and the cervical vestibular evoked myogenic potential (cVEMP) test. The objective was to investigate the sensitivity of the three vestibular tests to the presence of a vestibular schwannomas (VS), and possible correlations between test results, hearing acuity, and tumor size. Study Design: Retrospective cohort study. Setting: University hospital. ...
Wed May 13, 2020 07:38
Introduction: This study aimed to investigate the association between candidate genetic variants and audiometric measures of noise-induced hearing loss (NIHL) in young musicians. Methods: The study analyzed a database by Phillips et al. (Feasibility of a bilateral 4000–6000 Hz notch as a phenotype for genetic association analysis. Int J Audiol 2015;54:645–52.) which included behavioral hearing thresholds, distortion-product otoacoustic emissions (DPOAE), tympanometric, and genetic data of...
Wed May 13, 2020 07:38
Objective: To describe the first case of congenital external auditory canal cholesteatoma resected via a transcanal endoscopic approach and describe the possible pathologenesis of cholesteatoma. Patient: A 2-year-old female patient presented with a cholesteatoma that extended from the floor of the external auditory bony canal to the inferior quadrant of her right tympanic membrane. Intervention: Otological examinations and computed tomography were performed. The cholesteatoma was resected...
Wed May 13, 2020 07:38
Objective: Malleus ankylosis is an uncommon finding during stapes surgery, which can result in functional failure if undetected during primary surgery. Its management can be difficult and different approaches and solutions have been described to date, most of which require interruption of the ossicular chain. We report the management of such condition through a transcanal endoscopic technique, with preservation of ossicular chain integrity. Patients: The procedure was carried out in a patient...
Wed May 13, 2020 07:38
No abstract available
Wed May 13, 2020 07:38
Objective: To investigate the impact of configurations of the vertebrobasilar system on the incidence of idiopathic sudden sensorineural hearing loss (ISSNHL) and canal paresis (CP). Study Design: Retrospective case review. Setting: Tertiary referral center. Patients: Two hundred and forty-eight consecutive patients diagnosed with ISSNHL and 152 patients with unilateral CP of an uncertain cause who were managed between January 2011 and December 2017. The contralateral side of 144...
Wed May 13, 2020 07:38
Objective: To provide long-term follow up of a unique patient with history of massive petrous apex congenital cholesteatoma. Patient: 75-year-old man who presented at age 18 with left Gradenigo-like syndrome. Intervention: Staged left radical mastoidectomy and open transsphenoidal marsupialization. Followed with routine in-office cholesteatoma debridement. Main Outcome Measures: Bony erosion on computed tomography (CT), monitoring for new symptoms. Results: Interval development...
Wed May 13, 2020 07:38
Objective: Examine hearing preservation rates in cochlear implant recipients 72 years and older. Study Design: Retrospective case series. Setting: Tertiary otology/neurotology practice. Patients: Cochlear implant recipients 72 years and older who are candidates for hearing preservation and were implanted between April 2017 and June 2018 Intervention: Surgical/rehabilitative. Main Outcome Measures: Hearing was measured preoperatively and 6 months after cochlear implantation. ...
Wed May 13, 2020 07:38
Background: Categories of Auditory Performance II (CAP-II) is an established audiological test that consists of a rating scale that can be used for prospective assessment of the auditory performance of cochlear implant (CI) recipients. Objective: To create and validate an Arabic version of Categories of Auditory Performance scale II (CAP-II), and to evaluate its reliability. Methods: In this cross-sectional study, 30 post-CI children (patients’ group) along with 30 control subjects were...
Wed May 13, 2020 07:38
Objective: To report the initial surgical and audiological outcomes of three pediatric patients with severe inner ear malformations who were simultaneously implanted with cochlear and brainstem implants in the same surgical session. Study Design: Retrospective case review. Setting: Tertiary referral center. Patients: Three pediatric patients with severe inner ear malformations between ages of 1.9 to 2.5 years, who were simultaneously implanted with cochlear implant in one ear and...
Wed May 13, 2020 07:38
Hypothesis: Treatment modalities administered by Otolaryngologists vary based on patient volume and years of experience. Objective: It was our goal to evaluate the current trends in treatment modalities administered by Otolaryngologists based on patient volume and years of experience. Methods: An electronic questionnaire was distributed to all General Otolaryngologists and fellowship-trained Neurotologist members of the American Academy of Otolaryngology–Head and Neck Surgery (AAO-HNS)....
Wed May 13, 2020 07:38
Hypothesis: The objective was to evaluate the effect of cochlear implant (CI) insertion technique on electrode insertion forces and intracochlear trauma. We hypothesize that robotics-assisted insertions will reduce insertion forces and intracochlear trauma compared with manual insertions. Background: Variability in CI outcomes exists across patients, implant centers, surgeons, and electrode types. While surgical techniques that reduce electrode insertion trauma are well established, insertion...
Wed May 13, 2020 07:38
Hypothesis: Endolymphatic hydrops (EH) associated with cochlear implantation are associated with vestibular dysfunction. Background: Vestibular dysfunction is a known risk after cochlear implantation (CI). CI has been shown to cause cochlear hydrops due to fibrosis surrounding the ductus reuniens. However, the association of cochlear hydrops with vestibular hydrops and the relationship to vestibular symptoms remain unknown. Methods: Histopathological analysis and clinical evaluation...
Wed May 13, 2020 07:38
Objective: To describe the tip fold over rate, scalar localization, and speech perception outcomes of the CI532 Slim Modiolar Electrode. Patients and Intervention: All patients receiving the CI532 implant before June 2018. Main Outcome Measures: Outcome measures for adults patients include pre- and postoperative speech perception, operative report details, electrode position as determined by X-ray and cone beam computed tomography. Comparison made with previous experience with the Contour...
Wed May 13, 2020 07:38
Hearing Preservation Outcomes and Prognostic Factors in Acoustic Neuroma Surgery: Predicting Cutoffs
Objective: To investigate the outcomes of hearing preservation surgery (HPS) for acoustic neuroma and quantify tumor and patient characteristics predictive of hearing preservation after surgery. Study Design: Retrospective study. Setting: Tertiary referral center. Patients: A total of 100 consecutive patients diagnosed with acoustic neuroma from 2000 to 2012. Intervention: Hearing preservation surgery through microscopic retrosigmoid approach combined with a retrolabyrinthine...
Wed May 13, 2020 07:38
Objective: To assess the complication rate of magnetic resonance imaging (MRI) using 1.5 T scanners on cochlear implant (CI) and auditory brainstem implant (ABI) recipients over 14.5 years. Methods: Prospective study conducted in a tertiary referral center for cochlear and auditory brainstem implantation, including patients with neurofibromatosis 2. The primary outcome was complications related to MRI scanning in implant recipients, including failure to complete MRI sessions. The secondary...
Wed May 13, 2020 07:38
Objectives: The aim of the present study was to evaluate semicircular canal function by video Head Impulse Test (vHIT) in patients with facial nerve schwannoma (FNS). Study Design: Retrospective case review. Setting: Tertiary referral center. Patients: Seven patients with FNS underwent vHIT examination. Main Outcome Measures: The gain in vestibulo-ocular reflex and the presence of catch-up saccade were examined for the semicircular canals including the vertical canals. Results:...
Wed May 13, 2020 07:38
Objectives: To determine and compare the benefit of binaural hearing rehabilitation via cochlear implantation (CI) on speech perception, assessment of auditory abilities, tinnitus distress, health-related quality of life (HRQoL) and psychological comorbidities in patients suffering from asymmetric hearing loss (AHL) as well as bilaterally-deafened and sequentially bilaterally-implanted patients. Methods: 53 patients were implanted between 2011 and 2016. 24 AHL patients were implanted unilaterally,...
Wed May 13, 2020 07:38
Objective: To test whether the threshold of nerve integrity monitor (NIM) responses during facial nerve decompression surgery can predict the postoperative outcome. Study Design: Retrospective study. Setting: University hospital. Patients: Twenty peripheral facial palsy patients who underwent transmastoid decompression surgery. Intervention: During decompression surgery, thresholds of NIM responses were measured via direct facial nerve stimulation at three sites: the geniculate...
Wed May 13, 2020 07:38
Objective: To evaluate factors influencing the development of nonauditory percepts and facial nerve stimulation after cochlear implant (CI) activation. Study: Retrospective cohort study. Setting: Tertiary referral center. Patients: Over the course of 5 years, 433 consecutive patients were evaluated for CI and 518 ears were implanted. Of those, 497 ears had information regarding CI activation. Interventions: Lateral wall electrodes (LWE) or perimodiolar/mid-scalar electrodes...
Wed May 13, 2020 07:38
Objective: To assess mastoid geometry using computed tomography (CT) scans and design-based stereological methods. Background: The anatomical organization of the mastoid air cell system (MACS) remains debated. Geometrical parameters have previously been determined by automated image-analysis algorithms. Stereology is an alternative approach, which has previously been applied to estimate the volume of the MACS, but has not previously been used to estimate surface area or study anisotropy. ...
Wed May 13, 2020 07:38
Objectives: Evaluation of foreign language acquisition at school in cochlear implant patients. Study Design: Multicenter cohort study. Setting: CI centers. Patients: One hundred twenty-five CI users (10–18 yr) in the German-speaking part of Switzerland were enrolled. Demographic data were obtained by means of written questionnaires. German-speaking children with mainstream foreign language tuition (English and/or French) were enrolled for further testing. The control group of normal-hearing...
Wed May 13, 2020 07:38
No abstract available
Wed May 13, 2020 07:38
Objective: To compare outcomes of transcanal endoscopic tympanoplasty reconstructed using pretragal superficial musculoaponeurotic system (SMAS) fascia versus temporalis fascia. Study Design: Retrospective patient review and posttreatment questionnaire survey. Setting: Tertiary referral center. Patients: Sixty adult patients with chronic dry tympanic membrane perforation. Interventions: Patients underwent transcanal endoscopic type I tympanoplasty reconstructed using the SMAS...
Wed May 13, 2020 07:38
No abstract available
Wed May 13, 2020 07:38
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