Publication date: Available online 12 May 2020Source: Medical HypothesesAuthor(s): Giuseppe Magro
Wed May 13, 2020 16:52
Publication date: Available online 12 May 2020Source: Medical HypothesesAuthor(s): L.S.N.F. Luísa de Sousa Nogueira Freitas, F.R.S. Flavia Rodrigues da Silva, H.A.A. Henrique de Araújo Andrade, R.C.G. Renato Carvalho Guerreiro, F.V. Fernanda Viegas, M.T.M. Marco Túlio de Mello, A.S. Andressa Silva
Wed May 13, 2020 16:52
Publication date: Available online 12 May 2020Source: Medical HypothesesAuthor(s): Kevin S. Heffernan, Sae Young Jae
Wed May 13, 2020 16:52
MISCAST: MIssense variant to protein StruCture Analysis web SuiTe. Nucleic Acids Res. 2020 May 13;: Authors: Iqbal S, Hoksza D, Pérez-Palma E, May P, Jespersen JB, Ahmed SS, Rifat ZT, Heyne HO, Rahman MS, Cottrell JR, Wagner FF, Daly MJ, Campbell AJ, Lal D Abstract Human genome sequencing efforts have greatly expanded, and a plethora of missense variants identified both in patients and in the general population is now publicly accessible. Interpretation...
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Overview of herbal and traditional remedies in the treatment of cutaneous leishmaniasis based on Traditional Persian Medicine. Dermatol Ther. 2020 May 13;: Authors: Parvizi MM, Zare F, Handjani F, Nimrouzi M, Zarshenas MM Abstract This study aims to describe the herbal and traditional remedies in the treatment of Cutaneous leishmaniasis (CL) with an overview on related available evidence in modern medicine. This study is a review which focuses on the...
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Stereotactic laser anterior corpus callosotomy for Lennox-Gastaut syndrome. Epilepsia. 2020 May 13;: Authors: Tao JX, Satzer D, Issa NP, Collins J, Wu S, Rose S, Henry J, Santos de Lima F, Nordli D, Warnke PC Abstract OBJECTIVE: Corpus callosotomy is an effective palliative treatment for drug-resistant Lennox-Gastaut syndrome (LGS). Laser interstitial thermal therapy has been increasingly used in the treatment of epilepsy. Here, we assess the safety...
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Program of Active Consumer Engagement in Self-Management in Epilepsy: Replication and extension of a self-management randomized controlled trial. Epilepsia. 2020 May 13;: Authors: Johnson EK, Fraser RT, Lashley S, Barber J, Brandling-Bennett EM, Vossler DG, Miller JW, Caylor L, Warheit-Niemi T Abstract OBJECTIVE: The Program of Active Consumer Engagement in Self-Management in Epilepsy (PACES) is an evidenced-based self-management intervention for adults...
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The Efficacy and Tolerability of Levetiracetam as a First Line Monotherapy in Childhood Epilepsy. Ir Med J. 2020 Feb 13;113(2):18 Authors: Connolly A, Quirke M, Crowley S, Hayes E, Hurley C, Keegan M, Griffin G, Webb D Abstract Introduction To examine efficacy and tolerability of Levetiracetam monotherapy as a first line agent in a national cohort of children with epilepsy, naïve to anti-epileptic medication. Methods A retrospective analysis of children...
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Related ArticlesSeizures in autoimmune encephalitis: Kindling the fire. Epilepsia. 2020 May 13;: Authors: Wesselingh R, Butzkueven H, Buzzard K, Tarlinton D, O'Brien TJ, Monif M Abstract Epilepsy is a common neurological disorder that increases the risk of morbidity and mortality. Autoimmune epilepsy is a subset of epilepsy that occurs in the setting of autoimmunity, such as in autoimmune encephalitis (AIE). AIE is an autoimmune disorder characterized...
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Related ArticlesCorrection to: Routine diagnostics for neural antibodies, clinical correlates, treatment and functional outcome. J Neurol. 2020 May 12;: Authors: Bien CG, Bien CI, Dogan Onugoren M, De Simoni D, Eigler V, Haensch CA, Holtkamp M, Ismail FS, Kurthen M, Melzer N, Mayer K, von Podewils F, Rauschka H, Rossetti AO, Schäbitz WR, Simova O, Witt K, Höftberger R, May TW Abstract The original version of this article unfortunately contained a mistake.PMID:...
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Related ArticlesA review of clinically significant drug-drug interactions involving angiotensin II receptor antagonists and antiepileptic drugs. Expert Opin Drug Metab Toxicol. 2020 May 13;:1-9 Authors: Rusek M, Czuczwar SJ Abstract Introduction: Angiotensin II receptor blockers are widely used for the treatment of arterial hypertension and heart failure. However, recent studies on animal models of seizures showed that in the brain, the renin-angiotensin-aldosterone...
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Related ArticlesRapid versus slow withdrawal of antiepileptic drugs. Cochrane Database Syst Rev. 2020 01 23;1:CD005003 Authors: Ayuga Loro F, Gisbert Tijeras E, Brigo F Abstract BACKGROUND: The ideal objective of treating a person with epilepsy is to induce remission (free of seizures for some time) using antiepileptic drugs (AEDs) and withdraw the AEDs without causing seizure recurrence. Prolonged usage of AEDs may have long-term adverse effects. Hence,...
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Related ArticlesMacrophage Migration Inhibitory Factor Alters Functional Properties of CA1 Hippocampal Neurons in Mouse Brain Slices. Int J Mol Sci. 2019 Dec 31;21(1): Authors: Bancroft E, Srinivasan R, Shapiro LA Abstract Neuroinflammation is implicated in a host of neurological insults, such as traumatic brain injury (TBI), ischemic stroke, Alzheimer's disease, Parkinson's disease, and epilepsy. The immune response to central nervous system (CNS)...
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Related ArticlesComparison of machine learning models for seizure prediction in hospitalized patients. Ann Clin Transl Neurol. 2019 07;6(7):1239-1247 Authors: Struck AF, Rodriguez-Ruiz AA, Osman G, Gilmore EJ, Haider HA, Dhakar MB, Schrettner M, Lee JW, Gaspard N, Hirsch LJ, Westover MB, Critical Care EEG Monitoring Research Consortium (CCERMRC) Abstract OBJECTIVE: To compare machine learning methods for predicting inpatient seizures risk and determine...
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Related ArticlesElectroclinical features of insulo-opercular epilepsy: an SEEG and PET study. Ann Clin Transl Neurol. 2019 07;6(7):1165-1177 Authors: Wang X, Hu W, McGonigal A, Zhang C, Sang L, Zhao B, Sun T, Wang F, Zhang JG, Shao X, Zhang K Abstract OBJECTIVE: To report clinical experience with presurgical evaluation in patients with insulo-opercular epilepsy. Quantitative analysis on PET imaging and stereoelectroencephalography (SEEG) signals was...
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Related ArticlesTraditional uses, secondary metabolites, and pharmacology of Celastrus species - a review. J Ethnopharmacol. 2019 Sep 15;241:111934 Authors: Shen Y, Chen BL, Zhang QX, Zheng YZ, Fu Q Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Plants of genus Celastrus (Celastraceae) have been widely used in traditional Chinese medicine (TCM) and Indian medicine to treat cognitive dysfunction, epilepsy, insomnia, rheumatism, gout, and dyspepsia for thousands...
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Related ArticlesFactors associated with early seizures after surgery of unruptured intracranial aneurysms. Clin Neurol Neurosurg. 2019 03;178:93-96 Authors: Fushihara G, Kamide T, Kimura T, Takeda R, Ikeda T, Kikkawa Y, Araki R, Kurita H Abstract OBJECTIVE: The aim of the study was to better define the incidence of and risk factors for early seizures after repair of unruptured intracranial aneurysms in modern microsurgical techniques. PATIENTS...
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Related ArticlesWhat happens to temporal hypometabolism contralateral to side of surgery in patients with bilateral temporal hypometabolism? Clin Neurol Neurosurg. 2019 03;178:7-12 Authors: Alizada O, Akgun E, Akgun MY, Kemerdere R, Yeni SN, Tanriverdi T Abstract OBJECTIVE: To see what happens on PET hypometabolism on the temporal lobe contralateral to the side of surgery in patients with bitemporal hypometabolism (BTH). PATIENTS AND METHODS:...
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Related ArticlesLacosamide versus phenytoin for the prevention of early post traumatic seizures. J Crit Care. 2019 04;50:50-53 Authors: Kwon SJ, Barletta JF, Hall ST, Mangram AJ, Dzandu JK, Abdulhamid M, Zach V Abstract PURPOSE: To compare the efficacy and safety of lacosamide versus phenytoin for seizure prophylaxis following TBI. MATERIALS AND METHODS: All TBI patients who received prophylaxis with either phenytoin or lacosamide were retrospectively...
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Related ArticlesScreen Time Exposure and Altered Sleep in Young Children With Epilepsy. J Nurs Scholarsh. 2020 May 12;: Authors: Lin YY, Lee WT, Yang HL, Weng WC, Lee CC, Jeng SF, Tsai SY Abstract PURPOSE: To examine the association between daily screen time exposure and both sleep patterns (sleep onset, sleep offset, and nighttime, and daily sleep durations) and sleep disturbances among a clinical sample of children with epilepsy. DESIGN: A...
Wed May 13, 2020 14:11
Related ArticlesSubthalamic nucleus stimulation modulates motor epileptic activity in humans. Ann Neurol. 2020 May 12;: Authors: Ren L, Yu T, Wang D, Wang X, Ni D, Zhang G, Bartolomei F, Wang Y, Li Y Abstract OBJECTIVE: Pharmaco-refractory focal motor epileptic seizures pose a significant challenge. Deep brain stimulation (DBS) is recently a recognized therapeutic option for the treatment of refractory epilepsy. To identify the specific target for focal...
Wed May 13, 2020 14:11
Related ArticlesCenobamate (YKP3089) as adjunctive treatment for uncontrolled focal seizures in a large, phase 3, multicenter, open-label safety study. Epilepsia. 2020 May 12;: Authors: Sperling MR, Klein P, Aboumatar S, Gelfand M, Halford JJ, Krauss GL, Rosenfeld WE, Vossler DG, Wechsler R, Borchert L, Kamin M Abstract OBJECTIVE: During the development of cenobamate, an antiseizure medication (ASM) for focal seizures, three cases of drug reaction with...
Wed May 13, 2020 14:11
Related ArticlesThe postictal state - What do we know? Epilepsia. 2020 May 12;: Authors: Pottkämper JCM, Hofmeijer J, van Waarde JA, van Putten MJAM Abstract This narrative review provides a broad and comprehensive overview of the most important discoveries on the postictal state over the past decades as well as recent developments. After a description and definition of the postictal state, we discuss postictal sypmtoms, their clinical manifestations,...
Wed May 13, 2020 14:11
Related ArticlesVariable treatment response in a patient with pyridoxal N phosphate oxidase (PNPO) deficiency- understanding the paradox. Epilepsy Behav Rep. 2020;14:100357 Authors: Mohanlal S, Bindu PS, Sureshbabu S, Kumar S Abstract A 6-year-old girl presented with history of infantile onset epileptic encephalopathy and developmental delay. She had polymorphic seizures that were refractory to regular anti-seizure medication. Incomplete control of seizures...
Wed May 13, 2020 14:11
Related ArticlesAnti-seizure therapy with a long-term, implanted intra-cerebroventricular delivery system for drug-resistant epilepsy: A first-in-man study. EClinicalMedicine. 2020 May;22:100326 Authors: Cook M, Murphy M, Bulluss K, D'Souza W, Plummer C, Priest E, Williams C, Sharan A, Fisher R, Pincus S, Distad E, Anchordoquy T, Abrams D Abstract Background: A clinical feasibility study was undertaken at a single center of long-term intra-cerebroventricular...
Wed May 13, 2020 14:11
Related ArticlesA case of pyridoxine-dependent epilepsy with novel ALDH7A1 mutations. Oxf Med Case Reports. 2020 Mar;2020(3):omaa008 Authors: Dowa Y, Shiihara T, Akiyama T, Hasegawa K, Inoue F, Watanabe M Abstract Pyridoxine-dependent epilepsy (PDE) is a rare autosomal-recessive disorder typically presenting with neonatal seizures and is sometimes difficult to diagnose, because the clinical features mimic those of birth asphyxia. A Japanese newborn boy...
Wed May 13, 2020 14:11
Related ArticlesBlockade of cell volume regulatory protein NKCC1 increases TMZ-induced glioma apoptosis and reduces astrogliosis. Mol Cancer Ther. 2020 May 11;: Authors: Luo L, Guan X, Begum G, Ding D, Gayden J, Hasan N, Fiesler VM, Dodelson J, Kohanbash G, Hu B, Amankulor NM, Jia W, Castro MG, Sun B, Sun D Abstract Glioma is one of the most common primary malignant tumors of the central nervous system (CNS), accounting for approximately 40% of all intracranial...
Wed May 13, 2020 14:11
Related ArticlesBeneficial Effects of Hesperetin in a Mouse Model of Temporal Lobe Epilepsy. J Med Food. 2018 Dec;21(12):1306-1309 Authors: Kwon JY, Jung UJ, Kim DW, Kim S, Moon GJ, Hong J, Jeon MT, Shin M, Chang JH, Kim SR Abstract Abnormal reorganization of the dentate gyrus and neuroinflammation in the hippocampus represent characteristic phenotypes of patients suffering from temporal lobe epilepsy. Hesperetin, a flavanone abundant in citrus fruit,...
Wed May 13, 2020 14:11
Where does the cranial base flexion take place in humans? An Acad Bras Cienc. 2020;92(1):e20190825 Authors: Botelho RV, Botelho PB, Diniz JM Abstract The modern human has the most flexed cranial base among all living animals. The flexure allowed a larger cranial volume to accommodate a greater brain. Spheno-occipitalis synchondrosis (SOS) has been largely responsible for cranial base flexion, between the sphenoid and the Pars basilaris of the occipital...
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Role of Adjunct Treatments for Idiopathic CSF Leaks After Endoscopic Repair. Laryngoscope. 2020 May 13;: Authors: Sanghvi S, Sarna B, Alam E, Pasol J, Levine C, Casiano RR Abstract OBJECTIVE: A higher incidence of recurrent cerebrospinal fluid (CSF) leaks has been reported with idiopathic CSF leaks. A growing number of institutions advocate for routine use of intracranial pressure-lowering adjunct treatments after endoscopic repair. We report our results...
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Correlations of Online Search Engine Trends with Coronavirus disease (COVID-19) Incidence: Infodemiology Study. JMIR Public Health Surveill. 2020 May 13;: Authors: Higgins TS, Wu AW, Sharma D, Illing EA, Rubel K, Ting JY Abstract BACKGROUND: Coronavirus disease (COVID-19) is the latest pandemic of the digital age. With the Internet harvesting large amounts of data from the general population in real-time, public databases such as Google Trends (GT) and...
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Long-Term Outcomes from Blind Sac Closure of the External Auditory Canal: Our Institutional Experience in Different Pathologies. J Int Adv Otol. 2020 Apr;16(1):58-62 Authors: Kraus M, Hassannia F, J Bergin M, Al Zaabi K, Rutka JA Abstract OBJECTIVES: This study reports long-term results of blind sac closure of the external auditory canal performed for various pathologies, compares the complication rates and the need for revision surgery. MATERIALS...
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Related ArticlesCombined unilateral coronal-lambdoid suture synostosis: surgical outcome of suturectomy and postoperative helmet therapy. Childs Nerv Syst. 2020 May 12;: Authors: Hwang JH, Yang J, Kim KH, Phi JH, Kim SK, Wang KC, Lee JY Abstract INTRODUCTION: Nonsyndromic, multi-suture craniosynostosis is not common, especially those involving unilateral coronal and lambdoid sutures. Based on the experience on 6 cases, we analyzed the skull morphology...
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Related ArticlesPatterns of Bone Damage in Patients With Chronic Middle Ear Inflammation. Ear Nose Throat J. 2020 May 13;:145561320924144 Authors: Wiatr A, Strek P, Wiatr M Abstract BACKGROUND: Despite different etiologies, chronic otitis media involves the damaging and restructuring of bone tissue. The inflammatory process destroys elements of the ossicular chain, and bone lesions may appear that allow the development of otogenous complications. ...
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Related ArticlesMigration of a foreign object to the parapharyngeal space: an unusual factitious disorder. Braz J Otorhinolaryngol. 2020 Mar - Apr;86(2):261-263 Authors: Comoglu S, Enver N, Sen C, Aydemir L PMID: 27381878 [PubMed - indexed for MEDLINE]
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Related ArticlesComparison of a purely endoscopic three-layer technique versus pericranial flap for reconstruction of anterior skull base defects after sino-nasal tumor resection: assessment of postoperative frontal lobe sagging and frontal lobe falling. Rhinology. 2020 May 12;: Authors: Fiacchini G, De Santi S, Trico D, Cambi C, Seccia V, Cristofani-Mencacci L, Berrettini S, Bruschini L, Scarano M, Dallan I Abstract BACKGROUND: The evolution of endoscopic...
Wed May 13, 2020 14:22
Related ArticlesAnatomical Localization of Traumatic Brain Injury Cases in Eastern Macedonia and Thrace, Greece: a 10-year Retrospective Observational Study. Korean J Neurotrauma. 2020 Apr;16(1):38-48 Authors: Karakasi MV, Nikova AS, Valsamidou C, Pavlidis P, Birbilis TA Abstract Objective: Brain trauma is an extremely important economical and social issue with increasing daily incidence. It is important to observe and report brain trauma, in order to...
Wed May 13, 2020 14:22
Related ArticlesOsteoradionecrosis of the skull base. J Neurooncol. 2020 May 11;: Authors: Leonetti JP, Weishaar JR, Gannon D, Harmon GA, Block A, Anderson DE Abstract Radiation therapy (RT) is often necessary for the treatment of head and neck cancers. Osteoradionecrosis (ORN) is a rare, but potentially serious complication of RT. RT leads to the destruction of vasculature in radiated tissue causing hypoxia and tissue necrosis. ORN can occur in any...
Wed May 13, 2020 14:22
Related ArticlesSame viewing angle, minimal craniotomy enlargement, extreme exposure increase: the extended supraorbital eyebrow approach. Neurosurg Rev. 2020 May 11;: Authors: Martinez-Perez R, Albonette-Felicio T, Hardesty DA, Carrau RL, Prevedello DM Abstract The supraorbital eyebrow approach (SEa) has been commonly used as a straightforward route to reach lesions located in the anterior cranial fossa. The reduced surgical exposure provided by this...
Wed May 13, 2020 14:22
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