Related ArticlesThe role of immune checkpoint inhibitors in anaplastic thyroid cancer (Case Series). Oral Oncol. 2020 May 08;:104744 Authors: Sukari A, Kukreja G, Nagasaka M, Shukairy MK, Yoo G, Lin HS, Hotaling J, Kim H Abstract Anaplastic thyroid carcinoma (ATC) is a rare type of thyroid neoplasm. However, it is one of the most aggressive forms of malignancy accounting for approximately 50% of mortality associated with all thyroid cancers. Here we...
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Related ArticlesSoft Tissue Tumors of the Abdomen and Retroperitoneum. Surg Clin North Am. 2020 Jun;100(3):649-667 Authors: Turgeon MK, Cardona K Abstract Soft tissue tumors of the abdomen and retroperitoneum encompass a wide range of benign and malignant neoplasms. Retroperitoneal sarcomas, the most common, are composed of rare malignancies with numerous histiotypes. Surgery remains the cornerstone of treatment and the only curative option for retroperitoneal...
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Related ArticlesManagement of Gastric Adenocarcinoma for General Surgeons. Surg Clin North Am. 2020 Jun;100(3):523-534 Authors: Hoshi H Abstract Gastric cancer is one of the most common cancers in the world, despite declining incidence of the disease in the United States. Because of the rare occurrence of the disease in the United States, there is significant treatment variance in use of diagnostic modalities, neoadjuvant/adjuvant therapies, and surgical...
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Related ArticlesRNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia. Cell Stem Cell. 2020 May 10;: Authors: Shen C, Sheng Y, Zhu AC, Robinson S, Jiang X, Dong L, Chen H, Su R, Yin Z, Li W, Deng X, Chen Y, Hu YC, Weng H, Huang H, Prince E, Cogle CR, Sun M, Zhang B, Chen CW, Marcucci G, He C, Qian Z, Chen J Abstract N6-methyladenosine (m6A), the most abundant internal modification in mRNA,...
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Related ArticlesEarly-onset meningitis associated with atezolizumab treatment for non-small cell lung cancer: case report and literature review. Invest New Drugs. 2020 May 12;: Authors: Ogawa K, Kaneda H, Kawamoto T, Tani Y, Izumi M, Matsumoto Y, Sawa K, Suzumura T, Watanabe T, Mitsuoka S, Asai K, Kawaguchi T Abstract Immune checkpoint inhibitors (ICIs) have improved the overall survival of many patients with advanced cancers. However, unlike cytotoxic...
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Related ArticlesAmyloid-Rich Pancreatic Neuroendocrine Tumors: a Potential Diagnostic Pitfall in Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology (EUS-FNAC). Endocr Pathol. 2020 May 12;: Authors: Gambella A, Falco EC, Metovic J, Maletta F, De Angelis C, Maragliano R, Uccella S, Pacchioni D, Papotti M Abstract Pancreatic neuroendocrine tumors (PanNETs) are rare neoplasms that include even rarer variants that may pose different diagnostic problems,...
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Related ArticlesDiffuse Leiomyomatosis: Complete Myomectomy for Innumerable Small Nodules to Achieve Fertility Sparing and Childbearing. Surg J (N Y). 2020 May;6(Suppl 1):S50-S57 Authors: Konishi I Abstract Diffuse leiomyomatosis is a rare condition among benign smooth muscle neoplasms of the uterus, being defined as innumerable small myomatous nodules that mainly occur in the submucosal area. Young women with this disease suffer from menorrhagia, pains,...
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Related ArticlesRare Treatment for a Rare Tumor: Cryoablation of a Granular Cell Tumor. Gastrointest Tumors. 2020 Apr;7(1-2):41-49 Authors: Derstine L, Soule E, Shabandi N, Arutyunova Z, Lall C, Scuderi C, Matteo J Abstract Background: Granular cell tumors (GCTs) or Abrikossoff's tumors are rare neoplasms known to originate from Schwann cells in the peripheral nervous system. These lesions are usually benign; malignancy only occurs in 1-2% of cases....
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Related ArticlesNivolumab Induced Adrenal Insufficiency: Rare Side-effect of a New Anti-cancer Therapy - Immune-checkpoint Inhibitors. Cureus. 2020 Apr 10;12(4):e7625 Authors: Rai M, Go M Abstract Immune-checkpoint inhibitors are immuno-modulatory antibodies used in patients with advanced cancers like melanoma, renal cell carcinoma, non-small cell lung cancer, etc. They are associated with a wide array of side effects, commonly known as immune-related...
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Related ArticlesA Novel Combination of Metachronous Primary Malignancies of the Thyroid and Breast in a Patient with Neurofibromatosis Type 1. Cureus. 2020 Apr 08;12(4):e7590 Authors: Findakly D, Solsi A, Arslan W Abstract Neurofibromatosis 1 (NF1) is a genetic condition of variable presentations. It has been shown to increase the risk of multiple cancers. Therefore, NF1 has been identified as a tumor-provoking condition. We present a case of a 39-year-old...
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Related ArticlesCowden Syndrome Diagnosed by Bilateral Breast Cancer with Lhermitte-Duclos Disease: A Case Report. Case Rep Oncol. 2020 Jan-Apr;13(1):419-423 Authors: Morisaki T, Kashiwagi S, Kouhashi R, Yabumoto A, Asano Y, Takashima T, Hirakawa K, Ohira M Abstract Cowden syndrome is extremely rare and is characterized by multiple hamartomas in various tissues, including the skin, mucous membranes, gastrointestinal tract, breast, thyroid, and brain,...
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Related ArticlesA Rare Case of Systemic Mastocytosis with Associated Hematologic Neoplasm (SM-AHN) Involving Chronic Myeloid Leukemia: A Case Report and Literature Review. Am J Case Rep. 2020 May 13;21:e923354 Authors: Ibrahim FA, Abdulla MAJ, Soliman D, Al Sabbagh A, Nawaz Z, Akiki SJ, Shwaylia H, Yassin MA Abstract BACKGROUND Single or multiple cell line dysplasia is a characteristic feature of myelodysplastic syndrome. However, significant dysgranulopoiesis...
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Related ArticlesCD8+ T-cell encephalitis mimicking PRES in AIDS: a case report. BMC Neurol. 2020 May 12;20(1):179 Authors: Ishiguro M, Ueno Y, Ishiguro Y, Takanashi M, Murai K, Taieb G, Daida K, Suda A, Yokoyama K, Naito T, Hattori N Abstract BACKGROUND: Diverse mechanisms including infections, autoimmune inflammatory reactions, neoplasms, and degeneration are involved in the central nervous system in cases of acquired immune deficiency syndrome. In...
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Related Articles[Recurrent hemangioendothelioma of the lower and middle segments of inferior vena cava with spread to previously installed prosthesis]. Khirurgiia (Mosk). 2020;(4):65-69 Authors: Voskanyan SE, Shabalin MV, Artemyev AI, Kolyshev IY, Bashkov AN Abstract We report surgical treatment of a 65-year-old patient with recurrent hemangioendothelioma of inferior and middle segment of inferior vena cava with spread to previously established prosthesis....
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Related ArticlesToxic epidermal necrolysis after radiotherapy for pleomorphic liposarcoma. Dermatol Online J. 2020 Jan 15;26(1): Authors: Esaa FS, Hobson JG, Matar RN, Prieto PA, Somers KE Abstract Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are life-threatening, cutaneous reactions often associated with culprit drugs. A growing body of knowledge has deepened our understanding of the pathophysiology and clarified mechanisms such...
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Related ArticlesBenign symmetric lipomatosis in the tongue: an uncommon case. Dermatol Online J. 2020 Jan 15;26(1): Authors: Bastos DB, Figueira JA, Furuse C, Biasoli ÉR, Miyahara GI, Bernabé DG Abstract Symmetric lipomatosis of the tongue (SLT) is rare and characterized by diffuse growth and unencapsulated lipomas. An 87-year-old man was referred for evaluation of tongue lesions. Intraoral findings showed soft yellowish nodules with a smooth shiny surface...
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Related ArticlesLinear verrucous epidermal nevus with oral manifestations: report of two cases. Dermatol Online J. 2020 Jan 15;26(1): Authors: Gomes RT, Vargas PA, Tomimori J, Lopes MA, Santos-Silva AR Abstract Linear verrucous epidermal nevi (LVEN) are characterized by verrucous papules often coalescing into well-demarcated skin-colored or brown plaques following the lines of Blaschko. We present two new cases of LVEN with oral mucosa involvement and...
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Related Articles[Salivary ductal carcinoma of the parotid: A rare and agressive entity]. Cancer Radiother. 2020 Apr;24(2):135-137 Authors: Bouatay R, Harrathi K, Chefai J, Abdejlil N, Koubaa J Abstract We report a rare case of salivary duct carcinoma and we study its clinical and evolutionary features. A 64-year-old patient was referred for right peripheral facial paralysis. MRI showed suspected formation of the right parotid gland. Treatment included...
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Related ArticlesMyeloid Sarcoma That Infiltrated a Preexisting Sebaceous Lymphadenoma in the Parotid Gland: Diagnostic Challenges and Literature Review. Biomed Res Int. 2019;2019:9869406 Authors: Jo S, Shim HK, Kim JY, Bae SK, Kim MR Abstract Myeloid sarcoma (MS) is a rarely encountered extramedullary localized tumor that is composed of immature myeloid cells. We reported an extremely rare case of MS with concurrent bone marrow (BM) involvement that...
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Related ArticlesAdult soft tissue myoepithelial carcinoma: treatment outcomes and efficacy of chemotherapy. Med Oncol. 2019 Dec 27;37(2):13 Authors: Chamberlain F, Cojocaru E, Scaranti M, Noujaim J, Constantinou A, Thway K, Fisher C, Messiou C, Strauss DC, Miah A, Zaidi S, Benson C, Gennatas S, Jones RL Abstract Soft tissue myoepithelial carcinomas are a rare, malignant subgroup of myoepithelial tumours mostly arising in the extremities with equal predilection...
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Related ArticlesLong-Term Survival After Multidisciplinary Treatment Including Surgery for Metachronous Metastases of Small Intestinal Gastrointestinal Stromal Tumors after Curative Resection: A Case Report. Am J Case Rep. 2019 Dec 26;20:1942-1948 Authors: Katayanagi S, Yokoyama T, Makuuchi Y, Osakabe H, Iwamoto H, Sumi T, Hirano H, Katsumata K, Tsuchida A, Hirota S, Kawachi S Abstract BACKGROUND Currently, 3 molecular targeted drugs are available for...
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Related ArticlesA Case of Infected Left Atrial Myxoma Presenting as ST-Elevation Myocardial Infarction (STEMI). Am J Case Rep. 2019 Dec 24;20:1930-1935 Authors: Peters MJ, Tuwairqi KW, Farah MG Abstract BACKGROUND Although left atrial myxoma is the most common benign primary cardiac tumor, infected atrial myxoma is rare. This report presents a case of infected left atrial myxoma with embolization to the left anterior descending (LAD) coronary artery,...
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Related ArticlesBifocal Tibial Kaposiform Hemangioendothelioma Responsive to Vincristine Therapy: A Case Report. Am J Case Rep. 2019 Dec 23;20:1923-1929 Authors: Bsisu IK, Alkharabsheh MM, Al-Zu'bi BB, Almuhaisen G, Awidi AS, Samarah OQ Abstract BACKGROUND Kaposiform hemangioendothelioma is a rare locally aggressive vascular endothelial-derived spindle cells neoplasm. Herein, we report a rare case of bifocal tibial kaposiform hemangioendothelioma. CASE...
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Related ArticlesSyringoid Eccrine Carcinoma in the Abdominal Wall: A Rare Case Report and Literature Review. Am J Case Rep. 2019 Dec 19;20:1896-1901 Authors: Pereira MA, Pantaleão L, Rochael M Abstract BACKGROUND Syringoid eccrine carcinoma (SEC) is an extremely rare malignant adnexal neoplasm derived from eccrine sweat glands, of unknown pathogenesis. We report a case of this rare entity presenting in the abdomen, which is the only one reported in...
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Related ArticlesPrimary seminal vesicle adenocarcinoma: a lethal yet cryptic malignancy with review of literature. BMJ Case Rep. 2019 Dec 17;12(12): Authors: Bhat A, Banerjee I, Kryvenko ON, Satyanarayana R Abstract The rarity of primary seminal vesical adenocarcinoma (PSVA) coupled with mostly late and advanced presentation with high mortality makes it an unanticipated malignancy with poor prognosis. Although there has been sporadic reporting of cases,...
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Related ArticlesBlue rubber bleb nevus: a rare cause of GI bleeding-review of management. BMJ Case Rep. 2019 Dec 16;12(12): Authors: Ur Rashid M, Muhammad Khan M, Ullah W, Hussain I, Hurairah A Abstract Blue rubber bleb nevus syndrome (BRBNS) is a rare congenital vascular anomaly syndrome characterised by multifocal venous vascular malformations. It involves skin, central nervous systems, liver, muscles and gastrointestinal (GI) tract resulting in intestinal...
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Related ArticlesRare multifocal manifestation of solitary extramedullary plasmacytomas. BMJ Case Rep. 2019 Dec 15;12(12): Authors: Green J, Attwood C, Robbie H, Stefanidis K PMID: 31843778 [PubMed - indexed for MEDLINE]
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Related ArticlesChest wall lymph node metastasis from follicular thyroid carcinoma: a rare case report. Diagn Pathol. 2019 Nov 20;14(1):130 Authors: Li T, Ma Z, Lu C, Zhou Q, Feng Z, Wu X, Luo Y, Li D, Cheng X, Liu X Abstract BACKGROUND: Distant metastases from follicular thyroid carcinoma are mainly hematogenous and are commonly observed in the lungs and bones. Other rare sites are the parotid gland, skin, brain, ovary, adrenal gland, kidney, pancreas...
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Related ArticlesSignet ring cell variant of follicular thyroid carcinoma: Report of two cases with focus on morphological, expressional and genetic characteristics. Diagn Pathol. 2019 Nov 07;14(1):127 Authors: Hysek M, Jatta K, Stenman A, Darai-Ramqvist E, Zedenius J, Höög A, Juhlin CC Abstract BACKGROUND: Follicular thyroid carcinoma (FTC) is a neoplasm that presents with a micro-follicular growth pattern and a neutrally stained cytoplasm. Seldom,...
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Related ArticlesVulvar myeloid sarcoma as the presenting symptom of acute myeloid leukemia: a case report and literature review of Chinese patients, 1999-2018. Diagn Pathol. 2019 Nov 07;14(1):126 Authors: Zhang X, Huang P, Chen Z, Bi X, Wang Y, Wu J Abstract BACKGROUND: Myeloid sarcoma (MS), which represents a rare malignancy that comprises of myeloid blasts occurring at extra-medullary sites, closely correlates with the onset and relapse of acute...
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Related ArticlesVulvar Paget disease secondary to high-grade urothelial carcinoma with underlying massive vascular embolization and cervical involvement: case report of unusual presentation. Diagn Pathol. 2019 Nov 07;14(1):125 Authors: Primo WQSP, Primo GRP, Basilio DB, Machado KK, Carvalho JP, Carvalho FM Abstract BACKGROUND: Vulvar extramammary Paget disease is a rare chronic condition, that presents with non-specific symptoms such as pruritus and...
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Related ArticlesIdentification of CD5/Cyclin D1 Double-negative Pleomorphic Mantle Cell Lymphoma: A Clinicopathologic, Genetic, and Gene Expression Study. Am J Surg Pathol. 2020 02;44(2):232-240 Authors: Chuang WY, Chang ST, Yuan CT, Chang GJ, Chang H, Yeh CJ, Ueng SH, Kao HW, Wang TH, Wan YL, Shih LY, Chuang SS, Hsueh C Abstract Pleomorphic mantle cell lymphoma (PMCL) can closely mimic diffuse large B-cell lymphoma (DLBCL) morphologically, and expression...
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Related ArticlesA unique uterine cervical "teratocarcinosarcoma": a case report. Diagn Pathol. 2019 Nov 04;14(1):122 Authors: Ito K, Yano M, Ogasawara A, Miwa M, Kozawa E, Yasuda M Abstract BACKGROUND: Teratocarcinosarcoma (TCS) is a rare aggressive tumor of the nasal cavity and paranasal sinuses and has both epithelial and two or more mesenchymal components. In other organs, 5 cases of ovarian tumors closely resembling TCS have been reported; however,...
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Related ArticlesDasatinib-Induced Pulmonary Arterial Hypertension. Can J Cardiol. 2019 Nov;35(11):1604.e1-1604.e3 Authors: Orlikow E, Weatherald J, Hirani N Abstract A 73-year-old woman with chronic myeloid leukemia developed severe pulmonary arterial hypertension (PAH) and pleural effusions after treatment with dasatinib. During workup, partial anomalous pulmonary venous connection and a sinus venosus atrial septal defect were found; these anomalies...
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Related ArticlesPredictors of Outcome in Mammary Adenoid Cystic Carcinoma: A Multi-Institutional Study. Am J Surg Pathol. 2020 02;44(2):214-223 Authors: Slodkowska E, Xu B, Kos Z, Bane A, Barnard M, Zubovits J, Iyengar P, Faragalla H, Turbin D, Williams P, Barnes PJ, Mulligan AM Abstract Mammary adenoid cystic carcinoma (ACC) is a rare subtype of breast cancer with a favorable prognosis. Here we report on predictors of outcome based on a detailed morphologic...
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Related ArticlesMolecular Analysis of a Patient With Neurofibromatosis 2 (NF2) and Peritoneal Malignant Mesothelioma. Am J Surg Pathol. 2020 02;44(2):288-292 Authors: Glass C, Sholl LM, Landgraf JR, Chirieac L, Roggli VL Abstract Neurofibromatosis type 2 (NF2), an inherited disorder associated with multiple inherited schwannomas, meningiomas and ependymomas is caused by an autosomal dominant, likely loss of function germline mutation of the NF2 gene....
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Related ArticlesCutaneous metastasis as a primary presentation of a pulmonary enteric adenocarcinoma. Int J Biol Markers. 2019 Dec;34(4):421-426 Authors: Todisco A, Internò V, Stucci LS, Ostuni C, Lovero D, D'Oronzo S, Mele F, Duda L, Palmirotta R, Silvestris F Abstract BACKGROUND: Primary pulmonary enteric adenocarcinoma (PEAC) is a rare non-small cell lung cancer subtype sharing morphologic and immunohistochemical features with colorectal adenocarcinoma....
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Related ArticlesASO Author Reflections: Disease Patterns and Treatment of Adolescents and Young Women with Breast Cancer. Ann Surg Oncol. 2019 12;26(Suppl 3):735-736 Authors: Murphy BL, Boughey JC PMID: 31535300 [PubMed - indexed for MEDLINE]
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Related ArticlesASO Author Reflections: Using Big Data to Overcome the Challenges of Studying a Rare Tumor. Ann Surg Oncol. 2019 12;26(Suppl 3):727-728 Authors: Ayabe RI, Hernandez JM PMID: 31520211 [PubMed - indexed for MEDLINE]
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