The value of vestibular function tests combined with high stimulus rate auditory brainstem response in Vestibular Migraine

xlomafota13 shared this article with you from Inoreader The value of vestibular function tests combined with high stimulus rate auditory brainstem response in Vestibular Migraine Via Clinical Otolaryngology Abstract We retrospectively analysed the value of vestibular function tests combined with high stimulus rate auditory brainstem response in vestibular migraine. All patients were tested by caloric test, vHIT, and high stimulus rate ABR. The abnormal values of single test including caloric test, vHIT, and high stimulus rate ABR were low. The abnormal values of high stimulus rate ABR combined with vHIT were significantly higher than that of the other two groups. No significant differences among the three combined tests and high stimulus rate ABR combined with vHIT. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Expression of epithelial membrane protein (EMP) 1, EMP 2, and EMP 3 in thyroid cancer

xlomafota13 shared this article with you from Inoreader Expression of epithelial membrane protein (EMP) 1, EMP 2, and EMP 3 in thyroid cancer Via Cellular and Molecular Biology Histol Histopathol. 2021 Oct 7:18378. doi: 10.14670/HH-18-378. Online ahead of print. ABSTRACT Purpose Epithelial membrane protein (EMP) 1, EMP2, and EMP3 are expressed in various types of tumors and have been reported to be involved in carcinogenesis. In this study, we aimed to investigate the expression of these proteins in primary and metastatic thyroid cancer and its clinical implication. Methods EMP1, EMP2, and EMP3 immunohistochemistry was performed using tissue microarrays of 545 primary thyroid carcinomas [338 papillary thyroid carcinoma (PTC), 111 follicular carcinoma (FC), 69 medullary carcinoma (MC), 23 poorly differentiated carcinoma (PDC), and 4 anaplastic carcinoma (AC)] and 59 recurrent or metastatic PTCs. Results EMP1 showed high expression in AC, PTC, FC (P<0.001), and EMP2 was highly expressed in AC (P<0.001). EMP1 and EMP2 were not expressed in stromal cells. Expression of EMP3 in tumor cells [EMP3 (T)] was hig her in PDC, PTC, and AC (P<0.001), and expression in stromal cells [EMP3 (S)] was observed only in AC and PTC (P=0.001). The expression of EMP1 (P=0.002) and EMP3 (T) (P<0.001) was higher in conventional PTC than in follicular variant PTC. PTC with BRAF V600E mutation showed higher expression of EMP1 (P<0.001), EMP3 (T) (P<0.001), and EMP3 (S) (P=0.012) than PTC without BRAF V600E mutation. In the PTC without BRAF V600E mutation group, expression of EMP3 (S) was associated with shorter disease free survival (P=0.004). Metastatic PTC showed higher EMP2 (3.4% vs. 0%, P=0.022) and lower EMP3 (T) (44.1% vs. 66%, P=0.001) than primary PTC. Conclusions Expression of EMP1, EMP2, and EMP3 is different according to the subtypes of thyroid cancer. Further studies are needed to determine their role as prognostic markers and treatment target in thyroid cancer. PMID:34617578 | DOI:10.14670/HH-18-378 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Cricopharyngeal Achalasia Presenting as Acute Dysphagia in a Pediatric Patient

xlomafota13 shared this article with you from Inoreader Cricopharyngeal Achalasia Presenting as Acute Dysphagia in a Pediatric Patient Via otol rhinol Ann Otol Rhinol Laryngol. 2021 Oct 7:34894211050453. doi: 10.1177/00034894211050453. Online ahead of print. ABSTRACT OBJECTIVE: To describe a case of idiopathic cricopharyngeal achalasia (CPA) in a pediatric patient with acute onset of dysphagia managed conservatively with supportive care. METHODS: Sixteen-month-old boy presented with acute onset of gagging and coughing with feeding. His exam was notable for a well-appearing child with pooling of oral secretions and co arse breath sounds. Plain film series did not show radio-opaque foreign body (FB) and an esophagram demonstrated an endoluminal filling defect of the cervical esophagus and aspiration of contrast. He was taken to the operating room for urgent endoscopy but no FB or food impaction was observed. He had persistent symptoms that required further evaluation and a multidisciplinary team approach. Bedside laryngoscopy did not reveal any abnormalities. Modified barium swallow (MBS) study revealed upper esophageal sphincter (UES) dysfunction, consistent with cricopharyngeal achalasia. Repeat upper endoscopy with biopsies demonstrated mucosal irritation overlying the UES but histologic studies were negative for infectious causes. RESULTS: He was treated with supportive care, including nasogastric feedings for nutrition supplementation as he was unable to tolerate oral feedings without aspiration. Over the course of 3 months after discharge, his symptoms resolved and repeat MBS was norma l. CONCLUSION: CPA is a rare cause of dysphagia in the pediatric population. Conservative management with supportive care is a reasonable approach in cases with acute onset in otherwise healthy children without underlying medical problems. PMID:34617459 | DOI:10.1177/00034894211050453 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Surgical Preservation of Parathyroid Function During Total Thyroidectomy Can Be Improved by Intraoperative Imaging

xlomafota13 shared this article with you from Inoreader Surgical Preservation of Parathyroid Function During Total Thyroidectomy Can Be Improved by Intraoperative Imaging Via Clinical Thyroidology Clinical Thyroidology, Volume 33, Issue 10, Page 456-458, October 2021. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Ultrasound Appearance Does Not Improve Thyroid Cancer Risk Predicted by Molecular Testing

xlomafota13 shared this article with you from Inoreader Ultrasound Appearance Does Not Improve Thyroid Cancer Risk Predicted by Molecular Testing Via Clinical Thyroidology Clinical Thyroidology, Volume 33, Issue 10, Page 437-440, October 2021. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Hybrid [18F]FDG PET/MR Has High Sensitivity and Specificity in the Detection of Recurrent Differentiated Thyroid Cancer

xlomafota13 shared this article with you from Inoreader Hybrid [18F]FDG PET/MR Has High Sensitivity and Specificity in the Detection of Recurrent Differentiated Thyroid Cancer Via Clinical Thyroidology Clinical Thyroidology, Volume 33, Issue 10, Page 447-451, October 2021. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

K1-70 — A Thyrotropin Receptor Antagonist with Therapeutic Potential in Graves' Disease, Thyroid Eye Disease, and Differentiated Thyroid Cancer

xlomafota13 shared this article with you from Inoreader K1-70 — A Thyrotropin Receptor Antagonist with Therapeutic Potential in Graves' Disease, Thyroid Eye Disease, and Differentiated Thyroid Cancer Via Clinical Thyroidology Clinical Thyroidology, Volume 33, Issue 10, Page 433-436, October 2021. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Real-World Thyrotropin Suppression Practices for Low-Risk Papillary Thyroid Cancer Exceed Guideline Recommendations

xlomafota13 shared this article with you from Inoreader Real-World Thyrotropin Suppression Practices for Low-Risk Papillary Thyroid Cancer Exceed Guideline Recommendations Via Clinical Thyroidology Clinical Thyroidology, Volume 33, Issue 10, Page 441-443, October 2021. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Multiparametric Analysis of Speaking Fundamental Frequency in Genetically Related Speakers Using Different Speech Materials: Some Forensic Implications

xlomafota13 shared this article with you from Inoreader Multiparametric Analysis of Speaking Fundamental Frequency in Genetically Related Speakers Using Different Speech Materials: Some Forensic Implications Via Journal of Voice Objective: To assess the speaker-discriminatory potential of a set of fundamental frequency estimates in intraidentical twin pair comparisons and cross-pair comparisons (i.e., among all speakers). Participants: A total of 20 Brazilian Portuguese speakers of the same dialect, namely 10 male identical twin pairs aged between 19 and 35, were recruited. Method: the participants were recorded directly through professional microphones while taking part in a spontaneous dialogue over mobile phones. Acoustic measurements were performed in connected speech samples, and in lengthened vowels, at least 160 ms long produced during spontaneous speech. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Temporal bone computed tomography checklist-TeSLANO: introduction of a standardized preoperative imaging evaluation for middle ear surgery

xlomafota13 shared this article with you from Inoreader Temporal bone computed tomography checklist-TeSLANO: introduction of a standardized preoperative imaging evaluation for middle ear surgery Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Oct 7. doi: 10.1007/s00405-021-07112-w. Online ahead of print. ABSTRACT PURPOSE: Aim of the study was to evaluate if the introduction of the imaging checklist TeSLANO would improve the identification of crucial anatomical findings from temporal bone computed tomography (TBCT) scans among a cohort of Otolaryngology residents. STUDY DESIGN: Single-blinded prospective cohort study. SETTING: Tertiary care university hospital and referral center for otology and skull base surgery. METHODS: The cohort was composed by eight Otorhinolaryngology residents (four junior and four senior) that were individually asked to identify all relevant anatomic findings from preoperative TBCT scans. Supervising surgeon showed to each resident four TBCT scans before and four after the introduction of a systematic checklist evaluation system based on the TeSLANO acronym. Statistical analysis was performed using McNemar's test and results were considered significant with a P value < 0.05. RESULTS: Introduction of the checklist improved global identification of critical anatomical structures from 48.75 to 89.17% (P < 0.05). The postimplementation identification percentage improved for both the senior and junior groups (P < 0.05). CONCLUSIONS: The imaging checklist TeSLANO allows a systematic approach to review TBCT scans and significantly improves identification of critical anatomical structures in Otorhinolaryngology residents. PMID:34618226 | DOI:10.1007/s00405-021-07112-w View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Cells

	Albumin Might Attenuate Bacteria-Induced Damage on Kupffer Cells for Patients with Chronic Liver Disease Hao Lin et al.		The TGF-β/NADPH Oxidases Axis in the Regulation of Liver Cell Biology in Health and Disease Macarena Herranz-Itúrbide et al.
	Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders Stefano Sechi et al.		The Critical Role of Growth Factors in Gastric Ulcer Healing: The Cellular and Molecular Mechanisms and Potential Clinical Implications Andrzej S. Tarnawski et al.

To access all papers published in the latest issue, please see here.

#

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,

Telephone consultation 11855 int 1193,