Κυριακή 22 Οκτωβρίου 2017
Reply to correspondence ‘Topical ionic contra viral therapy comprised of digoxin and furosemide as a potential novel treatment approach for common warts’
We appreciate Dr Abdelmaksoud's thorough review of our manuscript (1) and would like to reply to the comments that were raised with this letter. First, it appears that the understanding is that the study describes the 'clinical response of common warts to a topical application of a fixed dose of 980 mg of the ICVT gel on the patients' lower back. It should be clarified that the main objective of this first-in-man study was evaluate the systemic exposure, safety and tolerability of ionic-contra-viral therapy (ICVT) (2).
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Spread of fluid: Role of tip configurations in needles
Abstract
Background/purpose
During the injection of a fluid in a tissue model, the fluid might be affected by the needle tip configuration and the number of channels. Thus, the objective of the present work is to observe the influence of different needle tips and number of channels on the spread of a fluid.
Methods
Fluid distribution data were obtained after injecting 0.3 mL of fluid into a foamed polymer model with a velocity of 2 mm/s. The spread area and the depth were determined for 3 different types of hypodermic needles: Single channel needles with bevel tip and blunt tip and a needle with conical tip and 3 internal channels.
Results
The bevel tip provides a higher spread in the direction where the bevel points and reaches larger depths than the other two needles. The spread for the blunt tip and the polymer needle is equally distributed on both sides of the needle. The largest horizontal area around the tip is achieved by the 3-channel needle.
Conclusion
The tip configuration and number of channels have an influence on the distribution of fluid. The bevelled needle directs the fluid and reaches larger depths compared with the 3-channel needle that gets more horizontal spread.
A feature fusion system for basal cell carcinoma detection through data-driven feature learning and patient profile
Abstract
Background
Basal cell carcinoma (BCC) is the most common skin cancer, which is highly damaging in its advanced stages. Computer-aided techniques provide a feasible option for early detection of BCC. However, automated BCC detection techniques immensely rely on handcrafting high-level precise features. Such features are not only computationally complex to design but can also represent a very limited aspect of the lesion characteristics. This paper proposes an automated BCC detection technique that directly learns the features from image data, eliminating the need for handcrafted feature design.
Methods
The proposed method is composed of 2 parts. First, an unsupervised feature learning framework is proposed which attempts to learn hidden characteristics of the data including vascular patterns directly from the images. This is done through the design of a sparse autoencoder (SAE). After the unsupervised learning, we treat each of the learned kernel weights of the SAE as a filter. Convolving each filter with the lesion image yields a feature map. Feature maps are condensed to reduce the dimensionality and are further integrated with patient profile information. The overall features are then fed into a softmax classifier for BCC classification.
Results
On a set of 1199 BCC images, the proposed framework achieved an area under the curve of 91.1%, while the visualization of learned features confirmed meaningful clinical interpretation of the features.
Conclusion
The proposed framework provides a non-invasive fast BCC detection tool that incorporates both dermoscopic lesional features and clinical patient information, without the need for complex handcrafted feature extraction.
Validation of digital photographic reference scales for evaluating facial aging signs
Abstract
Background
Validated tools are essential to evaluate facial skin aging for both dermatological and cosmetic investigations. While many visual aging scales have been developed, few have been validated and none in terms of degree of distinguishability (DD). We developed and validated a series of visual scales using a novel digital interface for scoring facial skin aging in Caucasian women.
Materials and methods
Three dermatologists independently established scales for 12 distinct aging signs from high-definition facial photographs of 400 adult women (Fitzpatrick phototypes I-IV) taken under standardized conditions. They then selected a consensus scale for each individual sign with a representative photo per grade. Scales were integrated into a digital interface allowing simultaneous viewing of all grades of each scale alongside the photograph of a test subject. Next, scales were validated by a different dermatologist, a general practitioner and a non-medical expert skin evaluator using photos of 350 women which had not been used for establishing the scales.
Results
Kappa estimates showed almost perfect agreement for wrinkle and skin aging scales (≥0.85) and moderate to substantial agreement for scales relating to color irregularities (telangiectasia, solar lentigines, freckles) for both inter- and intra-observer reproducibility. Intra-observer DD estimates were mostly high. Non-dermatologists performed well on reproducibility for both Kappa (from 0.6 to 0.9) and DD estimates.
Conclusion
Our work demonstrates that the digital interface scales for 12 distinct aging features are highly suitable for use in clinical and epidemiological studies on skin aging by both dermatologists and non-dermatologists.
Spectrophotometer is useful for assessing vitiligo and chemical leukoderma severity by quantifying color difference with surrounding normally pigmented skin
Abstract
Background
Acquired skin hypopigmentation has many etiologies, including autoimmune melanocyte destruction, skin aging, inflammation, and chemical exposure. Distinguishing lesions from normally pigmented skin is clinically important to precisely assess disease severity. However, no gold standard assessment method has been reported. We aimed to investigate whether spectrophotometers are useful for assessing vitiligo and rhododendrol (4-(4-hydroxyphenol)-2-butanol) (Rhododenol®)-induced leukoderma disease severity by quantifying skin color.
Methods
Mexameter® MX18 and CM-700d spectrophotometer were used for assessing vitiligo/leukoderma by measuring melanin index, L*a*b* color space, and ΔE*ab value, which represents the color difference between two subjects and is calculated by the values of L*a*b*.
Results
MX18 and CM-700d can quantitatively distinguish vitiligo/leukoderma from normally pigmented skin based on melanin index. CM-700d consistently quantified the color of vitiligo/leukoderma lesions and surrounding normally pigmented skin in L*a*b* color spaces and ΔE*ab. ΔE*ab is well correlated with melanin index and clinical appearance.
Conclusion
ΔE*ab has been frequently used in aesthetic dentistry; however, current study is the first to use it in the measurement of skin color. ΔE*ab seems to be a useful parameter to evaluate the color contrast between vitiligo/leukoderma and surrounding normally pigmented skin and can be used to evaluate disease severity and patient's quality of life.
Aseptic surgical preparation for upper eyelid blepharoplasty via full-face octenidine antiseptic without antibiotic medication shows effective prophylaxis against post-surgical wound infection
Abstract
Blepharoplasty is the third most common plastic surgical procedure in the USA. Due to the emergence of multiresistant bacteria, optimising the antiseptic procedure is crucial. Choice of antiseptics plays an important role as they may cause skin irritation and colouring of disinfected areas. In this study, the use of the aqueous antiseptic octenisept® (octenidine) was evaluated in the outcome of blepharoplasties: incidence of wound dehiscence; haematoma; and infection in correlation with gender, medication, smoking habits and time of year. This retrospective surveillance study included 352 patients (median age 58·3 years). Skin disinfection was performed thrice prior to blepharoplasty. Sutures were removed on day 6. None of the patients suffered from wound infection. The total rate of wound dehiscence was 6·3%, with a higher ratio among male patients. Smokers and patients on anticoagulant medication showed a significantly higher incidence of wound dehiscence. Throughout the year, rates of wound dehiscence were highest in summer. Aseptic surgical preparation for blepharoplasty via full-face scrub with octenisept® without oral antibiotic prophylaxis is well tolerated, with no report of wound infection, which may improve antibiotic stewardship as well as patient comfort. Elective upper eyelid blepharoplasty may ideally be performed in winter.
The efficacy of removable devices to offload and heal neuropathic plantar forefoot ulcers in people with diabetes: a single-blinded multicentre randomised controlled trial
Abstract
Non-removable offloading is the 'gold standard' treatment for neuropathic diabetic plantar forefoot ulcers. However, removable offloading is the common 'standard of care'. We compared three removable offloading devices for ulcer healing efficacy. In this multicentre, randomised controlled trial, 60 persons with neuropathic diabetic plantar forefoot ulcers were randomly assigned to wear a custom-made knee-high cast [BTCC (bivalved TCC)], custom-made ankle-high cast shoe or a prefabricated ankle-high forefoot-offloading shoe (FOS). Primary outcome was healing at 12 weeks. Dynamic plantar pressures, daily stride count and treatment adherence were assessed on a randomly selected subset (n = 35). According to intention-to-treat analysis, 58% of patients healed with BTCC [OR 0·77 (95% CI 0·41–1·45) versus FOS], 60% with cast shoe [OR 0·81 (95% CI 0·44–1·49) versus FOS] and 70% with FOS (P = 0·70). Mean ± SD peak pressure in kPa at the ulcer site was 81 ± 55 for BTCC, 176 ± 80 for cast shoe and 107 ± 52 for FOS (P = 0·005); stride count was 4150 ± 1626, 3514 ± 1380 and 4447 ± 3190, respectively (P = 0·71); percentage of 2-week intervals that patients wore the device <50% of time was 17·3%, 5·2% and 4·9%, respectively. Non-significant differences in healing efficacy between the three devices suggest that, when non-removable offloading is contraindicated or not available, each can be used for plantar forefoot ulcer offloading. Efficacy is lower than previously found for non-removable offloading maybe because suboptimal adherence and high stride count expose the patient to high repetitive stresses. These factors should be carefully considered in decision making regarding ulcer treatment.
Angiolymphoid hyperplasia with eosinophilia: report of nine cases
Abstract
Background
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a benign vascular proliferation characterized by dermal or subcutaneous red or brown papules or nodules, most commonly on the head and neck.
Objective
The aim of this study was to review the epidemiological and clinical characteristics of ALHE, focusing particularly on the histological and therapeutic features.
Methods
We performed a retrospective study of all cases of ALHE diagnosed in our dermatology and pathology departments between 2004 and 2015.
Results
Over 12 years, we collected nine cases of ALHE (0.75 case/year). There were four men and five women. The mean age was 43 years. Lesions presented as erythematous or violaceous papules or nodules in all cases, multiple in five cases, and localized on the head in eight cases or other sites in four cases. The diagnosis of ALHE was clinically suspected in only two cases. The histopathological findings showed an ill-circumscribed, intradermal slightly lobular proliferation of capillary-sized vessels around several central vessels. In all cases, the blood vessels were lined by large endothelial cells. An inflammatory infiltrate around the vessels was formed mainly of lymphocytes and eosinophils with isolated plasma cells and histiocytes. Surgery was the most common treatment in our series. Other local or general treatment has also been used with varying responses.
Conclusion
Angiolymphoid hyperplasia with eosinophilia is a rare epithelioid vascular tumor with a challenging clinical and histological diagnosis. Despite its benign nature, ALHE causes a therapeutic dilemma.
ALK-positive primary cutaneous anaplastic large cell lymphoma: a case report and review of the literature
Abstract
Anaplastic large cell lymphoma (ALCL) limited to the skin is a distinct disease that is designated primary cutaneous ALCL (pcALCL). It has an indolent course with a significantly better prognosis compared to systemic ALCL (sALCL). Anaplastic lymphoma kinase (ALK) expression in lesions of cutaneous ALCL is classically considered to be a marker for skin involvement by sALCL. However, recent reports of patients with ALK-positive pcALCL challenge this concept and raise prognostic and therapeutic dilemmas. Herein, we report a case of ALK-positive pcALCL in a 45-year-old woman who was treated with local radiotherapy. We review previously reported cases in the literature to better characterize this rare variant. Overall, the rates of cutaneous recurrence, systemic dissemination, and disease-related mortality in ALK-positive pcALCL do not differ from those previously reported in pcALCL. ALK-positive pcALCL is diagnosed at younger age and has a better disease course in children compared to adults with lower incidences of skin recurrence and progression to systemic disease. We conclude that ALK-positivity in cutaneous ALCL does not necessarily imply systemic disease. ALK-positive pcALCL has an excellent prognosis and should be treated by excision and/or radiotherapy. However, patients must remain under close long-term follow-up as recurrence and progression to systemic disease may occur.
08:17
Out of an abundance of caution, Earthbound Farm LLC of San Juan Bautista, CA is voluntarily recalling 1,755 cases of the Earthbound Farm Organic Chopped Asian Style Salad Kit with an expiration date of October 24, 2017 and UPC of 32601 95134, because it was discovered that some of the bags contain the...
08:17
This new clinical practice guideline from the American Dental Association (ADA) updates the 2010 guideline on “Evidence-based Clinical Recommendations Regarding Screening for Oral Squamous Cell Carcinomas The post Potentially malignant disorders of the oral cavity: Evaluation guideline appeared first...
08:15
Στην Αθήνα θα βρίσκονται από σήμερα και για μία εβδομάδα οι Θεσμοί, προκειμένου να συζητήσουν με την κυβέρνηση την Τρίτη Αξιολόγηση.
08:15
Summary: A new type of needle system combines 2 parts, an inner needle and an outer needle. The inner needle is used for filler injection and the outer needle acts as a guiding needle that can observe blood reflow when inserting into the vessel lumen during injection process. This new needle system can...
08:15
Background: The development of acellular dermal matrices (ADMs) has facilitated single-stage implant breast reconstruction (IBR) following skin-sparing mastectomy. The conventional approach of postpectoral implant placement with lower pole ADM confers a good cosmetic result by improving lower pole projection...
08:06
from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2xeANHq
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Sebastian Albrecht von Mammen, Daniel Wagner, Andreas Knote, Umut Taskin from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2yCYTji
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from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2yHX1Fd
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from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2yHX4kn
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from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2yI0Slx
08:06
BACKGROUND:Many studies have shown that depression increases mortality risk. We aimed to investigate the duration of time over which depression is associated with increased risk of mortality, secular trends in the association between depression and mortality, and sex differences in the association between...
08:06
from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2yHSv9E
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08:06
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08:06
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08:06
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08:06
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08:06
By Kelly Young Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH The rate of drug overdose deaths in rural America has overtaken that of cities, according to data in MMWR.Researchers examined survey and mortality … from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961...
08:06
By the Editors Here’s a quick look at what the NEJM Journal Watch bloggers are talking about right now: Insights on Residency … from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2hYZxxh
08:06
By the Editors Check out Monday’s selections from NEJM Group:NEJM Clinical Practice Center: Case Record: A 64-year-old man presented with headache, dyspnea, wheezing, … from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2zGPRiF
08:06
By the Editors The FDA has approved a second vaccine to prevent herpes zoster in adults aged 50 and older, the manufacturer announced on Friday. … from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2zIFefl
07:45
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07:36
Summary BackgroundsTreatment of mixed melasma remains challenging. Promising results have been achieved with low-fluence 1064-nm Q-switched Nd-YAG laser; however, multiple sessions are necessary with occurrence of complications especially in dark skin types. So, combination methods may be recommended....
07:36
Contributors : Chloe F Moss ; Ilaria D Rosa ; Martin A Reijns ; Martin S Taylor ; Ian J Holt ; Antonella SpinazzolaSeries Type : OtherOrganism : Mus musculusAll DNA polymerases misincorporate ribonucleotides despite their preference for deoxyribonucleotides, and analysis of cultured cells indicates...
07:36
Contributors : Mi Zhou ; Jianfeng ZhouSeries Type : Expression profiling by arrayOrganism : Mus musculusLittle is known about the roles of methyl-CpG-binding domain protein 2 (MBD2), a “reader” of DNA methylation, in T-cell acute lymphoblastic leukemia (T-ALL). Here, we investigated the role of MBD2...
07:36
Contributors : Yongyan Wu ; Qing Wei ; Zhiying Ai ; Zekun GuoSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Mus musculusIt has been demonstrated that SC1 (Pluripotin) promotes self-renewal of mouse embryonic stem cells. To better understand miRNAs regulated by SC1...
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Kylie L. Gorringe, Stephen B. Fox from # All Medicine by Alexandros G. Sfakianakis via alkiviadis.1961 on Inoreader http://ift.tt/2yHhyYJ
07:33
Food recall. For consumers, those two words send a red-flag alert: Don’t buy the recalled food or get rid of any of it you might have in your home. To retailers and food companies, the two words can strike fear in their hearts. “The food industry’s biggest threat to profitability,” read a recent headline...
07:23
A Texas dairy and a North Carolina cracker company are both on notice from the Food and Drug Administration for violations of federal food safety laws. The FDA sent warning letters to the companies in August and October, posting them for public view in recent days. Companies are allowed 15 working days...
07:16
Triple B Corporation of Seattle, Washington is voluntarily recalling salad kits and stir fry mixes due to possible contamination with Listeria monocytogenes, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune...
07:16
Triple B Corporation of Anchorage, Alaska is voluntarily recalling broccoli florette’s, stir fry kit, vegie trays w/ cauliflower, and a veggie pack combo, due to possible contamination with Listeria monocytogenes, an organism which can cause serious and sometimes fatal infections in young children, frail...
07:16
Meijer is announcing a recall of various packaged Meijer brand produce items due to a potential contamination with Listeria monocytogenes, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Although healthy...
07:16
In cooperation with the Mann Packing recall of minimally processed vegetable products due to possible Listeria monocytogenes contamination, Randalls, Tom Thumb and Albertsons stores in Texas, Louisiana and Arkansas only are voluntarily recalling Ready. Chef. Go! seafood meal bags. The bags include vegetables...
07:16
In cooperation with the Mann Packing recall of minimally processed vegetable products due to possible Listeria monocytogenes contamination, Albertsons, Safeway, Vons and Pak N’ Save stores in eight states are voluntarily recalling certain fresh vegetable trays and cups that include vegetables that are...
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Publication date: Available online 19 October 2017Source:Brazilian Journal of Otorhinolaryngology Author(s): Leonardo Silva from ! ORL Sfakianakis via paythelady.61 on Inoreader http://ift.tt/2xZoVJ6
07:14
Publication date: Available online 14 October 2017Source:Brazilian Journal of Otorhinolaryngology Author(s): Andressa Otranto de Britto Teixeira, Ana Luiza Ladeia Andrade, Rhita Cristina da Cunha Almeida, Marco Antonio de Oliveira AlmeidaIntroductionIntraoral devices have increasingly assumed...
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Publication date: Available online 19 October 2017Source:Brazilian Journal of Otorhinolaryngology Author(s): Kong Yew Liew, Abu Bakar ZulkifleeIntroductionNasopharyngeal Carcinoma is a geographically and racially variable disease which has a high incidence in Malaysia. Based on current concepts...
07:07
Other Plant Disease — United StatesAspergillus crown rot is on the rise in Georgia peanut fields and University of Georgia [UGA] researchers are working to pinpoint why. At present, scientists recommend that farmers stop saving seed from year to year to reduce the disease. If researchers can’t determine...
07:07
Brucellosis — ParaguayStudents of the Faculty of Veterinary Sciences of the National University of Asuncion were infected with brucellosis and they accused the authorities of not having been warned in time. The disease has its origin in animals. A veterinary student reported in Monumental AM that 2 of...
07:06
Could I 3D model and print a working airbrush in PLA? from Medicine via paythelady.61 on Inoreader http://ift.tt/2gYJCz8
06:47
Abstract Background Salmonella 4,[5],12:i:-, a worldwide emerging pathogen that causes many foodborne outbreaks mostly attributed to pig and pig products, is expanding in the U.S. Methods Whole genome sequencing was applied to conduct multiple comparisons of 659 S. 4,[5],12:i:- and 325 S. Typhimurium...
06:47
Abstract Background Understanding regional molecular epidemiology allows for the development of more efficient tuberculosis (TB) prevention strategies in low-incidence settings. Methods We analyzed 24-locus Mycobacterial Interspersed Repetitive Units-Variable Number of Tandem Repeats (MIRU-VNTR)...
06:47
Abstract Background Tuberculosis has been associated with an increased risk of cardiovascular disease, including acute myocardial infarction (AMI). We investigated whether latent tuberculosis infection (LTBI) associates with AMI. Methods We conducted a case-control study in two large national public...
06:46
Abstract Background Pneumococcal conjugate vaccines (PCVs) provide direct protection against disease in those vaccinated, and interrupt transmission through the prevention of nasopharyngeal carriage. Methods We analysed immunogenicity data from 5224 infants who received PCV in prime-boost schedules....
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06:46
Abstract Background Many health authorities recommend influenza vaccination of older adults to reduce disease burden. We hypothesized that in tropical and subtropical areas with more prolonged influenza seasons, twice-annual influenza vaccination might provide older adults with improved immunity...
06:46
Abstract Background Children born to mothers with placental malaria (PM) have been described as more susceptible to the occurrence of a first malaria infection. However, whether or not these children remain more at risk during infancy has never been explored. We aimed to determine if children born...
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06:20
Yohko Kitagawa | Shimon Sakaguchi from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/2yKOdyM via IFTTT
06:20
Irina Proekt | Corey N Miller | Michail S Lionakis | Mark S Anderson from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/2yKOd1K via IFTTT
05:52
Open rhinoplasty and Abbe flap techniques are traditionally useful tools for the reconstruction of secondary bilateral cleft lip nasal (BCLN) deformity. We aimed to investigate the long-term outcomes of simultaneous columella and philtrum reconstruction using prolabial flap combined with Abbe flap in...
05:52
Medical News Today Oral sex ups men’s risk of head and neck cancerEconomic Times New York, Oct 22 (IANS) Smoking and having oral sex with multiple partners may put men at increased risk of developing a type of head and neck cancer that is triggered by exposure to the human papilloma virus, known as...
05:24
Apart from brushing twice a day and flossing, what we eat plays a big role in keeping our teeth healthy. Australian dentist Dr Steven Lin, according to The Independent, has revealed which foods we should be consuming to do so. from ! ORL Sfakianakis via paythelady.61 on Inoreader http://ift.tt/2xX8YrT
04:49
Ο αριθμός των θερμίδων που λαμβάνεις καθημερινά από τη διατροφή σου και αυτός που «καις» χάρη στις διάφορες καθημερινές δραστηριότητες που κάνεις καθορίζει αν το βάρος σου θα αυξηθεί, θα μειωθεί ή θα παραμείνει σταθερό. Αν ο στόχος σου είναι να χάσεις κιλά, τότε πρέπει είτε να κάνεις… εκπτώσεις...
04:49
Είναι αυτή η εποχή του χρόνου που ξαφνικά ένα είναι το απαραίτητο αξεσουάρ σε μια τσάντα, τα χαρτομάντηλα. Οι μύτες κοκκινίζουν και «τρέχουν», ο λαιμός σε γδέρνει, η άμυνα του οργανισμού είναι στα τάρταρα και ο πυρετός μπορεί να γίνει κολλητός σου. Είτε πρόκειται για ένα κοινό κρυολόγημα είτε για γρίπη...
04:49
Για τις γυναίκες που διαγνώστηκαν κάποια στιγμή στη ζωή τους με καρκίνο του μαστού και κατάφεραν να τον νικήσουν, οι ανησυχίες για τυχόν επανεμφάνιση της νόσου στο μέλλον είναι έντονες και δικαιολογημένες. Μελέτη που δημοσιεύτηκε πρόσφατα στο επιστημονικό περιοδικό Journal of Clinical Oncology έδειξε...
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Ένα μεγάλο μέρος του πληθυσμού κυρίως μετά την ηλικία των 40 ετών, αναπτύσσει μεταβολικό σύνδρομο. Αυτό μπορεί να εξηγήσει γιατί κάποιος δεν νοιώθει καλά, έχει παραπανίσια κιλά, ενώ αυξάνει η πιθανότητα καρδιοπάθειας, διαβήτη και άλλων χρόνιων νοσημάτων. Κοινή αιτία της κεντρικού τύπου παχυσαρκίας...
04:48
Λίγο μετά τις δύο με τρεις το μεσημέρι πολλοί άνθρωποι αρχίζουν να έχουν μια έντονη νύστα συνήθως στη δουλειά. Η μόνη διέξοδος για αρκετούς φαίνεται να είναι ένας ακόμη καφές, προκειμένου ώστε να έρθουν σε πέρας τις υποχρεώσεις της ημέρας. Οι ειδικοί όμως προτείνουν μια άλλη λύση για να τονώσουμε...
04:48
Θεραπευτικό εμβόλιο για τον ιό των ανθρωπίνων θηλωμάτων (HPV) και τις βλάβες που προκαλεί, δοκιμάζεται σε περισσότερα από 100 κέντρα σε όλο τον κόσμο, όπως δήλωσε στο Πρακτορείο Fm και στην εκπομπή «104,9 Μυστικά Υγείας» ο μαιευτήρας-γυναικολόγος διδάκτωρ του Πανεπιστημίου Ιωαννίνων Ευριπίδης Μπιλιράκης....
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Publication date: February 2018Source:World Development, Volume 102 Author(s): James Berry, Dean Karlan, Menno PradhanGovernments and non-governmental organizations promote school-based financial literacy programs as means to instill financial behaviors that can persist through adulthood....
04:45
Στο 12% των επεμβάσεων βουβωνοκήλης παγκοσμίως είναι παρών ο χρόνιος πόνος. Για το λόγο αυτό, είναι σημαντική, η εμπειρία του χειρουργού, προκειμένου να αποφευχθεί…
04:45
Αν και μόνο στο άκουσμα της λέξης «γυμναστήριο» βγάζετε… σπυράκια, θα σας χαροποιήσει ιδιαίτερα να μάθετε ότι το Χάρβαρντ, ένα από τα κορυφαία πανεπιστήμια…
04:45
The dreaded Ebola had abruptly altered his destiny and dealt him a deadly blow never to be forgotten. Everyone simply pointed at him asý the orphan …
04:45
She’s navigated massive public health crises during her 10 years at the helm of the WHO, including Ebola and Zika outbreaks, and led the agency at a …
04:45
The Ebola virus outbreak of 2014 – 16 is a perfect example of just how damaging mixed messages can be to health care and disease containment …
04:45
A united stand: In the wake of the 2014-16 outbreak, an Ebola vaccine was developed jointly by a group of countries, NGOs and the WHO — and …
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Abstract Background Cyclophilin A (CyPA) and Emmprin play important roles in peri-implantitis. However, their roles in the diagnosis and treatment of the disease are still unclear. Purpose The aim of this split-mouth animal study was to describe variable trends of biomarkers during the...
03:20
Distribution – National. Recalling firm – Industry. from Medicine via paythelady.61 on Inoreader http://ift.tt/2zJ92IS
02:15
Foi divulgada hoje a notícia, via anúncio em redes sociais, de que a escaladora austríaca Angela Eiter conseguiu encadernar uma The post Escaladora encadena via de 12b (9b Fr) e confirma 2017 como o ano das mulheres na escalada appeared first on Revista Blog de Escalada. from Medicine via paythelady.61...
01:59
We read with great interest the recent article by Marin et al. (1) about the prevalence of restless legs syndrome (RLS) in post-polio syndrome (PPS). The authors reported RLS as highly prevalent (36%) in a large sample of PPS patients (n=119) with a marked disease severity, as measured by IRLSSS score,...
01:40
Elvira Chiccarelli grew up during the Vietnam War and felt a call to serve her country. Her mother had been a cadet nurse in World War II, and in 1975 Chiccarelli, a dentist, joined the Air Force. from ! ORL Sfakianakis via paythelady.61 on Inoreader http://ift.tt/2gZpblK
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Morgan Collins Sarner and Trevor James George were married Oct. 21 in New York. Rabbi Steven J. Meltz officiated at the Pierre hotel. from ! ORL Sfakianakis via paythelady.61 on Inoreader http://ift.tt/2zuBptt
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Age-Related Changes in Objective and Subjective Speech Perception in Complex Listening Environments.
Conclusions: Research supports the multifactorial nature of listening in real-world environments. Current audiologic assessment practices are often insufficient to identify the true speech understanding struggles that individuals experience in these situations. This points to the importance of giving...
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Conclusions: Results are discussed in terms of how growth estimates can be incorporated in recommendations for fostering productive language skills among CWS. The need for additional research on language in early stuttering and recovery is suggested. PMID: 29049493 [PubMed – as supplied by publisher]...
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Background Traumatic injury is the leading cause of paediatric morbidity and mortality in the USA. We present updated national data on emergency department (ED) discharges for traumatic injury for a recent 7-year period. Methods We conducted a descriptive epidemiological analysis of the Nationwide...
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Publication date: Available online 25 July 2018 Source: Journal of Photochemistry and Photobiology B: Biology Author(s): Marco Ballestr...
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Editorial AJR Reviewers: Heartfelt Thanks From the Editors and Staff Thomas H. Berquist 1 Share + Affiliation: Citation: American Journal...
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Publication date: Available online 28 September 2017 Source: Actas Dermo-Sifiliográficas Author(s): F.J. Navarro-Triviño
