Analytical ChemistryDOI: 10.1021/acs.analchem.0c01121
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00115
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00890
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Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c01809
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03447
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02227
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02973
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c00637
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02633
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Exp Clin Endocrinol DiabetesDOI: 10.1055/a-1149-9030 Aims The aim of this case report is to specify the frequency and mortality of Metformin-Associated Lactic Acidosis (MALA) in emergency medicine, as the diagnosis seems to occur more often than estimated. Methods To identify the subjects, we developed screening criteria for MALA. We measured the serum metformin concentration to confirm the diagnosis in all patients fulfilling these criteria. Retrospectively the patients were grouped according...
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Evolutionary biology aims to explain how new species arise and evolve to occupy myriad niches -- but it is not a singular or simplistic story. Rare bees found in high mountain areas of Fiji provide evidence that they have evolved into many species, despite the fact they can't readily adapt to different habitats. These bees -- discovered by a team of Australian researchers -- serve as a major warning about the impact of ongoing human-induced climate change and loss of biodiversity for different species.
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Abstract The aim of the study was a comprehensive assessment of metastatic breast cancer patients’ needs in Poland. We conducted and culturally adapted and validated “Count Us, Know Us, Join Us” Metastatic Breast Cancer Survey between November 2018 and July 2019. Two hundred ten patients treated in Tarnów completed the paper questionnaires distributed conveniently by healthcare professionals, and 110 patients completed the online survey. Almost all patients believe that new therapies...
Abstract To assess cancer survivors’ unmet supportive care needs and associated factors. Limited evidence is available about the supportive care needs of Chinese cancer survivors to inform future service planning. A cross-sectional survey was conducted (STROBE cross-sectional checklist used for report). Standardized questionnaires were administered to 364 cancer survivors. Using the Supportive Care Framework as conceptual framework, factors concerning individuals’ cognitive appraisals...
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Horm Metab Res 2020; 52: 305-315DOI: 10.1055/a-1153-0657It is reported that vitamin D deficiency is associated with carotid intima-media thickness (CIMT). In addition, several randomized clinical trials (RCTs) have studied the influence of vitamin D supplement on CIMT. However, results are inconclusive. This review aimed to systematically explore the potential link of the serum vitamin D level with CIMT pooling together observational studies and RCTs. PubMed and Scopus were searched for studies published...
Horm Metab Res 2020; 52: 280-288DOI: 10.1055/a-1142-8815Despite being the most common human neuroendocrine tumor, the pathogenesis of pituitary adenomas (PAs) is still unclear. Long non-coding RNA (lncRNA) is involved in a variety of physiological and pathological processes, and has been shown to play a key role in the process of tumor instigation and development by affecting the proliferation, migration, invasiveness, and metastasis of tumor cells. Therefore, lncRNAs may be used as diagnostic and...
Horm Metab Res 2020; 52: 336-339DOI: 10.1055/a-1149-9347Growth hormone releasing hormone is a hypothalamic neuropeptide, which regulates the release of growth hormone from the anterior pituitary gland. Growth hormone releasing hormone antagonists are anticancer agents, associated with strong anti-inflammatory activities. In the present study, we investigated the effects of the GHRH antagonist MIA-602 in the integrity of the brain microvascular endothelium in vitro. Our observations suggest that MIA-602...
Horm Metab Res 2020; 52: 298-304DOI: 10.1055/a-1151-2342Clinical studies investigating the relationship between fibroblast growth factor 23 (FGF23) and bone mass are controversial, especially in the healthy renal population. Our study is one of the forefronts investigating the relationship between FGF23 and bone mass parameters in the general population, according to age, sex, menopausal, and nutritional status. Cross-sectional study enrolling 123 volunteers between 20–80 years of age without primary...
Horm Metab Res 2020; 52: 316-321DOI: 10.1055/a-1128-6957The aim of the study was to evaluate the remission rate with short-term premixed insulin therapy in newly diagnosed type 2 diabetes outpatients and investigate predictors contributing to the remission rate. A 5-year prospective study was conducted with a total of 170 patients enrolled. Patients were treated with premixed insulin monotherapy or...
Horm Metab Res 2020; 52: 264-279DOI: 10.1055/a-1143-6024The associations between vascular endothelial growth factor (VEGF) gene polymorphisms and risk of type 2 diabetic retinopathy (DR) – proliferative diabetic retinopathy (PDR), and nonproliferative diabetic retinopathy (NPDR) – remain unclear. A systematic search and meta-analysis using odds ratio (OR) with 95% confidence interval (CI) was...
Horm Metab ResDOI: 10.1055/a-1157-0511Primary aldosteronism (PA) was reported to frequently harbor not only cardiovascular diseases but also some metabolic disorders including secondary calcium metabolic diseases. Recently, the potential association between aldosterone producing cells and systemic calcium metabolism has been proposed. For instance, PA is frequently associated with hypercalciuria or...
Horm Metab ResDOI: 10.1055/a-1164-1944Excess aldosterone is associated with the increased risk of cardio-/cerebrovascular events as well as metabolic comorbidities not only due to its hypertensive effect but also due to its proinflammatory action. Autonomous cortisol secretion (ACS) in the setting of primary aldosteronism (PA) is known to worsen cardiovascular outcome and potentially ...
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Authors: Jean-François Magnaval, Judith Fillaux, Sophie Cassaing, Alexis Valentin, Xavier Iriart and Antoine Berry.Parasite Vol. 27 , page 32Published online: 13/05/2020 Keywords: Human toxocariasis ; Atopy ; Outcome ; Clinical picture ; Eosinophilia ; IgE.
Authors: Céline Dard, Eve Tessier, Duc Nguyen, Loïc Epelboin, Dorothée Harrois, Christopher Swale, André Cabié, Katia de Meuron, Charline Miossec and Nicole Desbois-Nogard.Parasite Vol. 27 , page 31Published online: 12/05/2020 Keywords: Angiostrongylus cantonensis ; Angiostrongyliasis ; Eosinophilia ; Helminth ; Meningitis ; Encephalitis ; Caribbean ; Martinique.
Authors: Jean-François Magnaval, Judith Fillaux, Sophie Cassaing, Alexis Valentin, Xavier Iriart and Antoine Berry.<br />Parasite Vol. 27 , page 32<br />Published online: 13/05/2020<br /> Keywords: Human toxocariasis ; Atopy ; Outcome ; Clinical picture ; Eosinophilia ; IgE.<img src="http://feeds.feedburner.com/~r/edp_parasite/~4/864v3b-yL7c" height="1" width="1" alt=""/>
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Abstract Purpose An increase in PaCO2 is the element that defines sleep hypoventilation (SH). We queried if patients with SH, and those with PaCO2 increases during sleep for shorter time periods than SH (shamSH) differed from the patients without SH (noSH) in other ways. Methods This was a retrospective re-analysis of data from 100 stable inpatients...
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Abstract Purpose Hypothyroidism is associated with a lower metabolic rate, impaired glucose tolerance, and increased responsiveness of sympathetic nervous system to glucose ingestion. The Levothyroxine (LT4) monotherapy is the standard treatment for hypothyroidism; however to what extent this treatment restores the patients’ metabolism has not been verified. The aim of this study was to test the hypothesis that standard LT4 therapy...
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Publication date: Available online 13 May 2020Source: NeuroImageAuthor(s): Mahsa Dadar, Simon Duchesne, CCNA Group and the CIMA-Q Group
Publication date: Available online 13 May 2020Source: NeuroImageAuthor(s): Yu Liu, Junchen Li, Naying He, Yongsheng Chen, Zhijia Jin, Fuhua Yan, E. Mark Haacke
Publication date: Available online 12 May 2020Source: NeuroImageAuthor(s): Sunghyon Kyeong, Junhyung Kim, Joohan Kim, Eun Joo Kim, Hesun Erin Kim, Jae-Jin Kim
Publication date: Available online 12 May 2020Source: NeuroImageAuthor(s): Daniel E.P. Gomez, Alberto Llera, José P.R. F. Marques, Christian F. Beckmann, David G. Norris
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Background. Empowering the elderly by education programs can decrease medication problems, morbidity, and mortality. Methods. A cross-sectional study to identify trends and baseline medication management among the elderly in nursing homes followed by an interventional study (tailored educational programme) offered within the same population followed by reassessment of the same medication management domains. Results. There was no effect regarding nursing home participants’ medication knowledge before...
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