Cancers, Vol. 13, Pages 52: Comparative Efficacy and Safety of Anti-PD-1/PD-L1 Immune Checkpoint Inhibitors for Refractory or Relapsed Advanced Non-Small-Cell Lung Cancer—A Systematic Review and Network Meta-Analysis

xloma.fota13 shared this article with you from Inoreader Cancers, Vol. 13, Pages 52: Comparative Efficacy and Safety of Anti-PD-1/PD-L1 Immune Checkpoint Inhibitors for Refractory or Relapsed Advanced Non-Small-Cell Lung Cancer—A Systematic Review and Network Meta-Analysis Via Cancers Cancers, Vol. 13, Pages 52: Comparative Efficacy and Safety of Anti-PD-1/PD-L1 Immune Checkpoint Inhibitors for Refractory or Relapsed Advanced Non-Small-Cell Lung Cancer—A Systematic Review and Network Meta-Analysis Cancers doi: 10.3390/cancers13010052 Authors: Koichi Ando Ryo Manabe Yasunari Kishino Sojiro Kusumoto Toshimitsu Yamaoka Akihiko Tanaka Tohru Ohmori Tsukasa Ohnishi Hironori Sagara The efficacy and safety of immune checkpoint inhibitors (ICIs) in refractory or relapsed advanced non-small-cell lung cancer (NSCLC) have not yet been compared with those of ramucirumab (Ram) plus docetaxel (Doc). Furthermore, comprehensive comparisons between ICIs have not been conducted to date. In the current study, a Bayesian network meta-analysis of related phase III clinical trials was performed to compare the efficacy and safety of Ram+Doc, Niv, Atz, and Doc treatments in patient groups lacking the PD-L1 constraint. Surface under the cumulative ranking area (SUCRA) revealed that the overall survival (OS) of patients treated with Niv was the highest, followed by Atz, Ram+Doc, and Doc. Regarding grades 3–5 treatment-related adverse events (G3–5AEs), the use of Niv was ranked the safest, followed by Atz, Doc, and Ram+Doc. Significant differences in OS were observed between Niv and Ram+Doc, while significant differences in G3–5AEs were observed be tween Ram+Doc and Niv or Atz. In the PD-L1 positive (≥1%) patient subgroup, Pem (10 mg/kg) ranked the highest in efficacy for OS, followed by Niv, Pem (2 mg/kg), Atz, and Doc. These findings may expectedly provide oncologists with useful insights into therapeutic selection for refractory or relapsed advanced NSCLC. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

3D and 4D printing in dentistry and maxillofacial surgery: Printing techniques, materials, and applications

xloma.fota13 shared this article with you from Inoreader 3D and 4D printing in dentistry and maxillofacial surgery: Printing techniques, materials, and applications Via Acta Biomaterialia Publication date: Available online 26 December 2020 Source: Acta Biomaterialia Author(s): Danial Khorsandi, Amir Fahimipour, Payam Abasian, Sepehr Sadeghpour Saber, Mahla Seyedi, Sonya Ghanavati, Amir Ahmad, Andrea Amoretti De Stephanis, Fatemeh Taghavinezhaddilami, Anna Leonova, Reza Mohammadinejad, Majid Shabani, Barbara Mazzolai, Virgilio Mattoli, Franklin R. Tay, Pooyan Makvandi View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Postpancreatectomy hemorrhage with negative angiographic findings: outcomes of empiric embolization compared to conservative management

xloma.fota13 shared this article with you from Inoreader Postpancreatectomy hemorrhage with negative angiographic findings: outcomes of empiric embolization compared to conservative management Via Clinical Imaging Publication date: Available online 26 December 2020 Source: Clinical Imaging Author(s): Guan Yang, Zhang Jin-Long, Li Xiao-Hui, Wang Mao-Qiang View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Effects of Iron oxide particles on MRI and mammography in breast Cancer patients after a sentinel lymph node biopsy with paramagnetic tracers

xloma.fota13 shared this article with you from Inoreader Effects of Iron oxide particles on MRI and mammography in breast Cancer patients after a sentinel lymph node biopsy with paramagnetic tracers Via Clinical Imaging Publication date: Available online 26 December 2020 Source: Clinical Imaging Author(s): Erkin ARIBAL, Levent ÇELIK, Cem YILMAZ, Cem DEMIRKIRAN, Davut Can GUNER View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Quarternary α-cyanobenzylsulfonamides: A new subclass of CAA fungicides with excellent anti-Oomycetes activity

xloma.fota13 shared this article with you from Inoreader Quarternary α-cyanobenzylsulfonamides: A new subclass of CAA fungicides with excellent anti-Oomycetes activity Via ScienceDirect Publication: Bioorganic & Medicinal Chemistry Publication date: 15 January 2021 Source: Bioorganic & Medicinal Chemistry, Volume 30 Author(s): Daniel Stierli, Martin Eberle, Clemens Lamberth, Olivier Jacob, Dirk Balmer, Tanja Gulder View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Stereotactic Radiosurgery for Vestibular Schwannomas: Tumor Control Probability Analyses and Recommended Reporting Standards

xloma.fota13 shared this article with you from Inoreader Stereotactic Radiosurgery for Vestibular Schwannomas: Tumor Control Probability Analyses and Recommended Reporting Standards Via International Journal of Radiation Oncology*Biology*Physics Publication date: Available online 26 December 2020 Source: International Journal of Radiation Oncology*Biology*Physics Author(s): Scott G. Soltys, Michael T. Milano, Jinyu Xue, Wolfgang A. Tomé, Ellen Yorke, Jason Sheehan, George X. Ding, John P. Kirkpatrick, Lijun Ma, Arjun Sahgal, Timothy Solberg, John Adler, Jimm Grimm, Issam El Naqa View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Small animal IMRT using 3D printed compensators

xloma.fota13 shared this article with you from Inoreader Small animal IMRT using 3D printed compensators Via International Journal of Radiation Oncology*Biology*Physics Publication date: Available online 26 December 2020 Source: International Journal of Radiation Oncology*Biology*Physics Author(s): Gage Redler, Erik Pearson, Xinmin Liu, Inna Gertsenshteyn, Boris Epel, Charles Pelizzari, Bulent Aydogan, Ralph Weichselbaum, Howard J. Halpern, Rodney D. Wiersma View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Radiotherapy alone for human papillomavirus-related squamous cell carcinoma of the oropharynx: a single-arm, phase 2 study

xloma.fota13 shared this article with you from Inoreader Radiotherapy alone for human papillomavirus-related squamous cell carcinoma of the oropharynx: a single-arm, phase 2 study Via International Journal of Radiation Oncology*Biology*Physics Publication date: Available online 26 December 2020 Source: International Journal of Radiation Oncology*Biology*Physics Author(s): Norihiko Takemoto, Yuji Seo, Susumu Nakahara, Yasuo Yoshioka, Teruki Teshima, Takashi Fujii, Fumiaki Isohashi, Keisuke Otani, Tadashi Yoshii, Yukinori Takenaka, Motoyuki Suzuki, Takahito Fukusumi, Atsushi Hanamoto, Toshimichi Yasui, Takahiro Michiba, Yoshifumi Yamamoto, Shigetoshi Shimamoto, Hidenori Tanaka, Mitsuaki Tatsumi, Kazuhiko Ogawa View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

WbaP is required for swarm motility and intramacrophage multiplication of Salmonella Enteritidis spiC mutant by glucose use ability

xloma.fota13 shared this article with you from Inoreader WbaP is required for swarm motility and intramacrophage multiplication of <em>Salmonella</em> Enteritidis <em>spiC</em> mutant by glucose use ability Via ScienceDirect Publication: Microbiological Research Publication date: Available online 26 December 2020 Source: Microbiological Research Author(s): Yaonan Wang, Guifeng Liu, Jian Zhang, Dan Gu, Maozhi Hu, Yunzheng Zhang, Zhiming Pan, Shizhong Geng, Xin'an Jiao View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Diffusion tensor imaging of oral carcinoma: Clinical evaluation and comparison with histopathological findings 1

xloma.fota13 shared this article with you from Inoreader Diffusion tensor imaging of oral carcinoma: Clinical evaluation and comparison with histopathological findings <sup>1</sup> Via Magnetic Resonance Imaging Publication date: Available online 26 December 2020 Source: Magnetic Resonance Imaging Author(s): Ichiro Yamada, Norio Yohino, Misaki Yokokawa, Yu Oikawa, Hiroyuki Harada, Keigo Hikishima, Tohru Kurabayashi, Yukihisa Saida, Ukihide Tateishi, Yae Ohata View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Cancers, Vol. 13, Pages 53: Prognostic Clinical and Biologic Features for Overall Survival after Relapse in Childhood Medulloblastoma

xloma.fota13 shared this article with you from Inoreader Cancers, Vol. 13, Pages 53: Prognostic Clinical and Biologic Features for Overall Survival after Relapse in Childhood Medulloblastoma Via Cancers Cancers, Vol. 13, Pages 53: Prognostic Clinical and Biologic Features for Overall Survival after Relapse in Childhood Medulloblastoma Cancers doi: 10.3390/cancers13010053 Authors: Sophie Huybrechts Gwénaël Le Teuff Arnault Tauziède-Espariat Caroline Rossoni Anaïs Chivet Émilie Indersie Pascale Varlet Stéphanie Puget Rachid Abbas Olivier Ayrault Léa Guerrini-Rousseau Jacques Grill Dominique Valteau-Couanet Christelle Dufour Given the very poor prognosis for children with recurrent medulloblastoma, we aimed to identify prognostic factors for survival post-relapse in children with childhood medulloblastoma. We retrospectively collected clinico-biological data at diagnosis and main clinical characteristics at relapse of children newly diagnosed with a medulloblastoma between 2007 and 2017 at Gustave Roussy and Necker Hospital. At a median follow-up of 6.6 years (range, 0.4–12.3 years), relapse occurred in 48 out 155 patients (31%). The median time from diagnosis to relapse was 14.3 months (range, 1.2–87.2 months). Relapse was local in 9, metastatic in 22 and combined (local and metastatic) in 17 patients. Second-line treatment consisted of chemotherapy in 31 cases, radiotherapy in 9, SHH-inhibitor in four and no treatment in the remaining four. The 1-year overall survival rate post-relapse was 44.8% (CI 95%, 31.5% to 59.0%). While molecular subgrouping at diagnosis was significantly associated with survival post-relapse, the use of radiotherapy at relapse and time to first relapse (>12 months) might also have a potential impact on post-relapse survival. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Additive manufacturing of wood flour/polyhydroxyalkanoates (PHA) fully bio-based composites based on micro-screw extrusion system

xloma.fota13 shared this article with you from Inoreader Additive manufacturing of wood flour/polyhydroxyalkanoates (PHA) fully bio-based composites based on micro-screw extrusion system Via ScienceDirect Publication: Materials & Design Publication date: 1 February 2021 Source: Materials & Design, Volume 199 Author(s): Jing Tian, Run Zhang, Yihui Wu, Ping Xue View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Sirt1 activation negatively regulates overt apoptosis in Mtb-infected macrophage through Bax

xloma.fota13 shared this article with you from Inoreader Sirt1 activation negatively regulates overt apoptosis in <em>Mtb</em>-infected macrophage through Bax Via ScienceDirect Publication: International Immunopharmacology Publication date: February 2021 Source: International Immunopharmacology, Volume 91 Author(s): Hong Yang, Jianxia Chen, Yanghaoyu Chen, Yan Jiang, Baoxue Ge, Ling Hong View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.