Publication date: Available online 4 April 2019Source: Clinical ImagingAuthor(s): Elaine Schattner
Publication date: Available online 4 April 2019Source: Clinical ImagingAuthor(s): Vandana Dialani, Thanissara Chansakul, Kenny Lai, Hannah Gilmore, Natalie Yvonne Sayegh, Priscilla J. SlanetzAbstractPurposeCore biopsy-proven fibroadenomas that enlarge on clinical or imaging follow-up are often surgically excised to exclude an associated malignancy. The purpose of this study was to assess how often malignancy is detected upon excision, and to determine whether excision of enlarging, biopsy-proven,...
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Abstract Purpose The first aim of this study was to evaluate 68Ga-PSMAHBED-CC conjugate 11 positron emission tomography (PSMA PET) parameters for assessment of response to 177Lu-PSMA-617 radioligand therapy (RLT) in patients with metastatic castration-resistant prostate cancer (mCRPC). The second aim was to investigate factors associated with overall survival (OS). ...
The authors regret to inform the readers that one of the author's name in the original publication of this article was spelled incorrectly as Victor Casar-Pullicino. The correct spelling is Victor N. Cassar-Pullicino and is now presented correctly in this article.
The article Digital vs. analog PET/CT: intra-subject comparison of the SUVmax in target lesions and reference regions, written by Francisco Fuentes-Ocampo, Diego Alfonso López-Mora, Albert Flotats, Gabriela Paillahueque
Abstract Purpose Niemann-Pick type C (NPC) is a cholesterol storage disease characterized by disruption in the endosomal–lysosomal transport system that leads to the accumulation of cholesterol and glycolipids in lysosomes. Developmental cognitive delay and progressive motor and cognitive impairment are characteristic of the disease. Tau accumulation has been reported in some NPC patients. We investigated the presence of tau and...
Abstract Purpose Concomitant treatment with radium-223 and paclitaxel is a potential option for cancer patients with bone metastases; however, myelosuppression risk during coadministration is unknown. This phase Ib study in cancer patients with bone metastases evaluated the safety of radium-223 and paclitaxel. Methods Eligible patients had solid...
Abstract Purpose To evaluate the use of 68Ga-PSMA PET/CT for monitoring response to 177Lu-617 PSMA radioligand therapy in patients with metastatic castrate-resistant prostate cancer (mCRPC). Methods Patients from the University Hospital Bonn and the University Hospital Aachen were retrospectively reviewed for this study. We included 48 patients...
Abstract Purpose The prognosis for patients with inoperable esophageal carcinoma is still poor and the reliability of individual therapy outcome prediction based on clinical parameters is not convincing. In a recent publication, we were able to show that PET can provide independent prognostic information in such a patient group and that the tumor-to-blood standard uptake ratio (SUR) can improve the prognostic value of tracer uptake values....
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Objectives Comparison of the diagnostic value of simultaneous multislice (SMS) accelerated diffusion-weighted echo planar imaging (EPI) of malignant and benign lesions of the breast compared with a reference EPI sequence. Materials and Methods The study was approved by the institutional ethics committee. Sixty-eight patients were examined with a diffusion-weighted EPI (reference EPI; TE = 54 milliseconds; TR = 9000 milliseconds; TA, 3:27 minutes) and a diffusion-weighted SMS accelerated EPI...
Recent innovations in magnetic resonance, involving both hardware and software, that effectively deal with motion—whether inadvertent on the part of the patient or due to respiration and cardiac contraction—are reviewed, emphasizing major current advances. New technology involving motion sensing (kinetic, respiratory, and beat) is enabling simpler, faster, and more robust monitoring of the sources of motion. This information is being integrated, with new innovative imaging approaches, to effectively...
Objectives The aims of this study were to assess the discriminative performance of quantitative multiparametric magnetic resonance imaging (mpMRI) between prostate cancer and noncancer tissues and between tumor grade groups (GGs) in a multicenter, single-vendor study, and to investigate to what extent site-specific differences affect variations in mpMRI parameters. Materials and Methods Fifty patients with biopsy-proven prostate cancer from 5 institutions underwent a standardized preoperative...
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Atherosclerosis is one of the leading causes of death and disability worldwide. It is a complex disease characterized by lipid accumulation within the arterial wall, inflammation, local neoangiogenesis, and apoptosis. Innate immune effectors, in particular monocytes and macrophages, play a pivotal role in atherosclerosis initiation and progression. Although most of available evidence on the role of monocytes and macrophages in atherosclerosis is derived from animal studies, a growing body of evidence...
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Publication date: Available online 6 April 2019Source: Medical Image AnalysisAuthor(s): Eldad Rubinstein, Moshe Salhov, Meital Nidam-Leshem, Valerie White, Shay Golan, Jack Baniel, Hanna Bernstine, David Groshar, Amir AverbuchAbstractEarly detection and localization of prostate tumors pose a challenge to the medical community. Several imaging techniques, including PET, have shown some success. But no robust and accurate solution has yet been reached. This work aims to detect prostate cancer foci...
Publication date: Available online 4 April 2019Source: Medical Image AnalysisAuthor(s): Talha Qaiser, Yee-Wah Tsang, Daiki Taniyama, Naoya Sakamoto, Kazuaki Nakane, David Epstein, Nasir RajpootAbstractTumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles (PHPs). For a given image patch, the homology profiles are derived...
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Publication date: Available online 6 April 2019Source: NeuroImageAuthor(s): Lukasz Smigielski, Milan Scheidegger, Michael Kometer, Franz X. VollenweiderAbstractBoth psychedelics and meditation exert profound modulatory effects on consciousness, perception and cognition, but their combined, possibly synergistic effects on neurobiology are unknown. Accordingly, we conducted a randomized, double-blind, placebo-controlled study with 38 participants following a single administration of the psychedelic...
Publication date: Available online 6 April 2019Source: NeuroImageAuthor(s): Gerhard S. Drenthen, Walter H. Backes, Albert P. Aldenkamp, Jacobus F.A. JansenAbstractNon-invasive quantification of the in vivo myelin content may provide valuable information regarding healthy maturation of the brain, as well as insights into demyelination of several neurological disorders. However, these scans are often long thereby limiting acquisition of large brain parts in clinically feasible acquisition times. Therefore,...
Publication date: Available online 6 April 2019Source: NeuroImageAuthor(s): Manish Saggar, Hua Xie, Roger E. Beaty, Atanas D. Stankov, Meredith Schreier, Allan L. ReissAbstractDevelopmental research has found that children's creative thinking ability tends to decline during middle childhood. However, this decline has not been consistently demonstrated, and the underlying neural and behavioral factors that affect fluctuations in children's creative thinking ability remain uncharacterized. Using a...
Publication date: Available online 5 April 2019Source: NeuroImageAuthor(s): Lena K.L. Oestreich, Roshini Randeniya, Marta I. GarridoAbstractAuditory prediction errors, i.e. the mismatch between predicted forthcoming auditory sensation and actual input, trigger detection of surprising auditory events in the environment. Auditory mismatches engage a hierarchical functional network of cortical sources, which are also interconnected by auditory white matter pathways. Hence it is plausible that these...
Publication date: Available online 5 April 2019Source: NeuroImageAuthor(s): Peng Wang, Florian Göschl, Uwe Friese, Peter König, Andreas K. EngelAbstractThe integration of sensory signals from different modalities requires flexible interaction of remote brain areas. One candidate mechanism to establish communication in the brain is transient synchronization of oscillatory neural signals. Although there is abundant evidence for the involvement of cortical oscillations in brain functions based on the...
Publication date: Available online 5 April 2019Source: NeuroImageAuthor(s): Aina Puce
Publication date: Available online 5 April 2019Source: NeuroImageAuthor(s): Duan Li, George A. MashourAbstractKetamine is a unique drug that has psychedelic and anesthetic properties in a dose-dependent manner. Recent studies have shown that ketamine anesthesia appears to maintain the spatiotemporal complexity of cortical activation evoked by transcranial magnetic stimulation, while a psychedelic dose of ketamine is associated with increased spontaneous magnetoencephalographic signal diversity. However,...
Publication date: Available online 5 April 2019Source: NeuroImageAuthor(s): Jess E. Reynolds, Melody N. Grohs, Deborah Dewey, Catherine LebelAbstractWhite matter development continues throughout childhood and into early adulthood, but few studies have examined early childhood, and the specific trajectories and regional variation in this age range remain unclear. The aim of this study was to characterize developmental trajectories and sex differences of white matter in typically developing young children....
Publication date: Available online 5 April 2019Source: NeuroImageAuthor(s): Matthew S. Sherwood, Jason G. Parker, Emily E. Diller, Subhashini Ganapathy, Kevin B. Bennett, Carlos R. Esquivel, Jeremy T. NelsonAbstractIn this work, we investigated the use of real-time functional magnetic resonance imaging (fMRI) with neurofeedback training (NFT) to teach volitional down-regulation of the auditory cortex (AC) using directed attention strategies as there is a growing interest in the application of fMRI-NFT...
Publication date: Available online 4 April 2019Source: NeuroImageAuthor(s): Ottavia Dipasquale, Pierluigi Selvaggi, Mattia Veronese, Anthony S. Gabay, Federico Turkheimer, Mitul A. MehtaAbstractOne of the main limitations of pharmacological fMRI is its inability to provide a molecular insight into the main effect of compounds, leaving an open question about the relationship between drug effects and haemodynamic response. The aim of this study is to investigate the acute effects of 3,4-methylenedioxymethamphetamine...
Publication date: Available online 4 April 2019Source: NeuroImageAuthor(s): Ethan Oblak, James Sulzer, Jarrod Lewis-PeacockAbstractThe neural correlates of specific brain functions such as visual orientation tuning and individual finger movements can be revealed using multivoxel pattern analysis (MVPA) of fMRI data. Neurofeedback based on these distributed patterns of brain activity presents a unique ability for precise neuromodulation. Recent applications of this technique, known as decoded neurofeedback,...
Publication date: Available online 4 April 2019Source: NeuroImageAuthor(s): Christopher A. Brown, Frederick A. Schmitt, Charles D. Smith, Brian T. GoldAbstractExecutive function (EF) performance in older adults has been linked with functional and structural profiles within the executive control network (ECN) and default mode network (DMN), white matter hyperintensities (WMH) burden and levels of Alzheimer's disease (AD) pathology. Here, we simultaneously explored the unique contributions of these...
Publication date: Available online 4 April 2019Source: NeuroImageAuthor(s): Zachary A. Yaple, W. Dale Stevens, Marie ArsalidouAbstractWorking memory, a fundamental cognitive function that is highly dependent on the integrity of the prefrontal cortex, is known to show age-related declines across the typical healthy adult lifespan. Moreover, we know from work in neurophysiology that the prefrontal cortex is disproportionately susceptibly to the pathological effects of aging. The n-back task is arguably...
Publication date: Available online 4 April 2019Source: NeuroImageAuthor(s): Svenja Espenhahn, Bernadette C.M. van Wijk, Holly E. Rossiter, Archy O. de Berker, Nell D. Redman, Jane Rondina, Joern Diedrichsen, Nick S. WardAbstractPeople vary in their capacity to learn and retain new motor skills. Although the relationship between neuronal oscillations in the beta frequency range (15–30 Hz) and motor behaviour is well established, the electrophysiological mechanisms underlying individual differences...
Publication date: Available online 4 April 2019Source: NeuroImageAuthor(s): Samuel R. Krimmel, Michael G. White, Matthew H. Panicker, Frederick S. Barrett, Brian N. Mathur, David A. SeminowiczAbstractStructural and functional analyses of the human claustrum, a poorly understood telencephalic gray matter structure, are hampered by its sheet-like anatomical arrangement. Here, we first describe a functional magnetic resonance imaging (fMRI) method to reveal claustrum signal with no linear relationship...
Publication date: Available online 4 April 2019Source: NeuroImageAuthor(s): Nicole S. McKay, David Moreau, Dion T. Henare, Ian J. KirkAbstractA single nucleotide polymorphism (SNP) in the gene coding for brain-derived neurotrophic factor (BDNF) has previously been associated with a reduction in recognition memory performance. While previous findings have highlighted that this SNP contributes to recognition memory, little is known about its influence on subprocesses of recognition, familiarity and...
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The published version of this article unfortunately contained a mistake. Author name Mariana Z. Meyers was incorrect. The correct middle initial is given above.
Abstract Background There is a paucity of available literature describing the frequency of technical success of liver two-dimensional (2-D) ultrasound (US) shear wave elastography (SWE) in children and young adults. Objective To determine the frequency of technical success of liver 2-D ultrasound (US) SWE in children and young adults based on the interquartile...
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Publication date: Available online 6 April 2019Source: Academic RadiologyAuthor(s): Vincent M. Mellnick
Publication date: Available online 5 April 2019Source: Academic RadiologyAuthor(s): David Mark Yousem
Publication date: Available online 5 April 2019Source: Academic RadiologyAuthor(s): Stamatia Destounis
Publication date: Available online 5 April 2019Source: Academic RadiologyAuthor(s): Renee W. Pinsky
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Publication date: Available online 6 April 2019Source: Revista Española de Medicina Nuclear e Imagen MolecularAuthor(s): Á. de Bonilla Damiá, R. Fernández López, I. Acevedo Báñez, C. Calderón Cabrera, A. Molinos Quintana, I. Borrego Dorado
Sun Apr 07, 2019 13:26
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Publication date: Available online 6 April 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Edward Peake, Shaun Warrington, Nicholas J. Dudley, Paul S. Morgan, Nicholas M. GibsonAbstractUrethane-based test objects are routinely used for ultrasound quality assurance because of their durability and robustness. The acoustic properties of these phantoms including speed of sound and attenuation, however, have a strong dependence on temperature. Reliable measurement of low-contrast penetration,...
Publication date: Available online 5 April 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Sook Sam Leong, Jeannie Hsiu Ding Wong, Mohammad Nazri Md Shah, Anushya Vijayananthan, Maisarah Jalalonmuhali, Kwan Hoong NgAbstractThe purpose of this study was to assess the potential of shear wave elastography (SWE) as an indicator of abnormal kidney function defined by radiolabeled glomerular filtration rate (GFR). Fifty-seven patients referred for 51Cr-ethylenediaminetetraacetic acid GFR and...
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