Pathogens, Vol. 9, Pages 385: Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment Pathogens doi: 10.3390/pathogens9050385 Authors: Riccardo Miggiano Menico Rizzi Davide M. Ferraris Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited...
Mon May 18, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 100: Formulation and Evaluation of Loperamide HCl Oro Dispersible Tablets Pharmaceuticals doi: 10.3390/ph13050100 Authors: Blasco Alejandro Torrado Guillermo Peña M Ángeles This work proposes the design of novel oral disintegrating tablets (ODTs) of loperamide HCl with special emphasis on disintegration and dissolution studies. The main goal was augmenting the adherence to treatment of diseases which happen with diarrhea in soldiers who are exposed...
Mon May 18, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 99: Upregulated and Hyperactivated Thalamic Connexin 43 Plays Important Roles in Pathomechanisms of Cognitive Impairment and Seizure of Autosomal Dominant Sleep-Related Hypermotor Epilepsy with S284L-Mutant α4 Subunit of Nicotinic ACh Receptor Pharmaceuticals doi: 10.3390/ph13050099 Authors: Kouji Fukuyama Masashi Fukuzawa Motohiro Okada To understand the pathomechanism and pathophysiology of autosomal dominant sleep-related hypermotor epilepsy (ADSHE),...
Mon May 18, 2020 03:00
Pharmaceutics, Vol. 12, Pages 462: Enhanced Intestinal Absorption of Insulin by Capryol 90, a Novel Absorption Enhancer in Rats: Implications in Oral Insulin Delivery Pharmaceutics doi: 10.3390/pharmaceutics12050462 Authors: Hiroki Ukai Kazuki Iwasa Takamasa Deguchi Masaki Morishita Hidemasa Katsumi Akira Yamamoto Labrasol® is a self-emulsifying excipient that contains saturated polyglycolysed C6–C14 glycerides and this additive is known to improve the...
Mon May 18, 2020 03:00
Pharmaceutics, Vol. 12, Pages 461: Redox-Sensitive Linear and Cross-Linked Cystamine-Based Polymers for Colon-Targeted Drug Delivery: Design, Synthesis, and Characterisation Pharmaceutics doi: 10.3390/pharmaceutics12050461 Authors: Yoke Mooi Ng Mat Yusuf Hock Ing Chiu Vuanghao Lim Cystamine-based polymers may help to achieve controlled and targeted drug delivery to the colon due to their susceptibility to breakage of the disulfide linkage in the low redox potential environment...
Mon May 18, 2020 03:00
Pharmaceutics, Vol. 12, Pages 460: Enhancement of the Physical Stability of Amorphous Sildenafil in a Binary Mixture, with either a Plasticizing or Antiplasticizing Compound Pharmaceutics doi: 10.3390/pharmaceutics12050460 Authors: Justyna Knapik-Kowalczuk Krzysztof Chmiel Justyna Pacułt Klaudia Bialek Lidia Tajber Marian Paluch The main purpose of this paper was to evaluate the impact of both high- and low-Tg polymer additives on the physical stability of an amorphous...
Mon May 18, 2020 03:00
Pharmaceutics, Vol. 12, Pages 458: Highly Elastic and Water Stable Zein Microfibers as a Potential Drug Delivery System for Wound Healing Pharmaceutics doi: 10.3390/pharmaceutics12050458 Authors: Alma Akhmetova Georg-Marten Lanno Karin Kogermann Martin Malmsten Thomas Rades Andrea Heinz The development of biomaterials for wound healing applications requires providing a number of properties, such as antimicrobial action, facilitation of cell proliferation, biocompatibility...
Mon May 18, 2020 03:00
Pharmaceutics, Vol. 12, Pages 459: Predictive Value of Precision-Cut Kidney Slices as an Ex Vivo Screening Platform for Therapeutics in Human Renal Fibrosis Pharmaceutics doi: 10.3390/pharmaceutics12050459 Authors: Emilia Bigaeva Nataly Puerta Cavanzo Elisabeth G. D. Stribos Amos J. de Jong Carin Biel Henricus A. M. Mutsaers Michael S. Jensen Rikke Nørregaard Anna M. Leliveld Igle J. de Jong Jan-Luuk Hillebrands Harry van Goor Miriam Boersema Ruud A....
Mon May 18, 2020 03:00
Plasma, Vol. 3, Pages 59-91: Spectroscopic Measurements of Dissolved O3, H2O2 and OH Radicals in Double Cylindrical Dielectric Barrier Discharge Technology: Treatment of Methylene Blue Dye Simulated Wastewater Plasma doi: 10.3390/plasma3020007 Authors: Emile Salomon Massima Mouele Jimoh. O. Tijani Milua Masikini Ojo. O. Fatoba Chuks P. Eze Chionydua T. Onwordi Myo Tay Zar Myint Htet Htet Kyaw Jamal Al-Sabahi Mohammed Al-Abri Sergey Dobretsov Katri Laatikainen...
Mon May 18, 2020 03:00
Religions, Vol. 11, Pages 248: Monastic Form-of-Life Out of Place: Ritual Practices among Benedictine Oblates Religions doi: 10.3390/rel11050248 Authors: Thomas Quartier Although ritual participation in Christian churches is decreasing in the Netherlands, one of the most secularised countries in the world, monasteries are increasingly attractive to people not committed to a life in an abbey, but who rather transfer monastic practices to their personal life. Guesthouses are full, reading...
Mon May 18, 2020 03:00
Risks, Vol. 8, Pages 48: Testing the Least-Squares Monte Carlo Method for the Evaluation of Capital Requirements in Life Insurance Risks doi: 10.3390/risks8020048 Authors: Massimo Costabile Fabio Viviano In this paper, we test the efficiency of least-squares Monte Carlo method to estimate capital requirements in life insurance. We choose a simplified Gaussian evaluation framework where closed-form formulas are available and allow us to obtain solid benchmarks. Extensive numerical...
Mon May 18, 2020 03:00
Robotics, Vol. 9, Pages 36: Advances in Robotics and Mechatronics Robotics doi: 10.3390/robotics9020036 Authors: Yukio Takeda Giuseppe Carbone Shaoping Bai Robotics and Mechatronics technologies have become essential for developing devices/machines to support human life and society [...]
Mon May 18, 2020 03:00
Sci. Pharm., Vol. 88, Pages 25: Medication Safety in Intravenous Therapy: A Compatibility Study and Analysis of Reaction Products of Dihydralazine and Metamizole Scientia Pharmaceutica doi: 10.3390/scipharm88020025 Authors: Anna Katharina Koller Oliver Fischer Sabine Krebs Markus R. Heinrich Frank Dörje The pharmacotherapy of critically ill patients is challenging due to the variety of drugs that have to be applied. As the majority of pharmaceuticals must be administered...
Mon May 18, 2020 03:00
Sports, Vol. 8, Pages 68: Heart Rate Responses during Sport-Specific High-Intensity Circuit Exercise in Child Female Gymnasts Sports doi: 10.3390/sports8050068 Authors: Andreas Salagas Olyvia Donti Christos Katsikas Gregory C. Bogdanis This study examined heart rate (HR) responses during a sport-specific high-intensity circuit training session to indirectly assess cardiorespiratory stress in child athletes. Seventeen, female gymnasts, aged 9–11 years performed two...
Mon May 18, 2020 03:00
Sports, Vol. 8, Pages 66: Physical and Physiological Responses of U-14, U-16, and U-18 Soccer Players on Different Small-Sided Games Sports doi: 10.3390/sports8050066 Authors: Jorge López-Fernández Javier Sánchez-Sánchez Jorge García-Unanue Enrique Hernando Leonor Gallardo As most existing studies in youth academies are focused on top players, the objective of this research is to analyze the physical and physiological demands of various small-sided games (SSGs) on different...
Mon May 18, 2020 03:00
Sports, Vol. 8, Pages 65: Mechanisms of Hamstring Strain Injury: Interactions between Fatigue, Muscle Activation and Function Sports doi: 10.3390/sports8050065 Authors: Shaun Huygaerts Francesc Cos Daniel D. Cohen Julio Calleja-González Marc Guitart Anthony J. Blazevich Pedro E. Alcaraz Isolated injury to the long head of biceps femoris is the most common type of acute hamstring strain injury (HSI). However, the precise hamstring injury mechanism (i.e., sprint-type)...
Mon May 18, 2020 03:00
Sports, Vol. 8, Pages 67: Lean Body Mass, Muscle Architecture, and Performance in Well-Trained Female Weightlifters Sports doi: 10.3390/sports8050067 Authors: Nikolaos Zaras Angeliki-Nikoletta Stasinaki Polyxeni Spiliopoulou Marios Hadjicharalambous Gerasimos Terzis Lean mass and quadriceps muscle architecture have been associated with performance in male well-trained weightlifters, but no data exist for female weightlifters. The aim of the study is to investigate the relationship...
Mon May 18, 2020 03:00
Sports, Vol. 8, Pages 64: Time Course of Recovery for Performance Attributes and Circulating Markers of Muscle Damage Following a Rugby Union Match in Amateur Athletes Sports doi: 10.3390/sports8050064 Authors: Bruno Victor Corrêa da Silva Mário Antônio de Moura Simim Rodrigo Barboza da Silva Edmar Lacerda Mendes Bernardo Neme Ide Moacir Marocolo Jeffrey S. Martin Gustavo R. Mota Background: We sought to determine the time course of changes in neuromuscular performance...
Mon May 18, 2020 03:00
Urban Science, Vol. 4, Pages 26: Biometric Pilot-Studies Reveal the Arrangement and Shape of Windows on a Traditional Façade to be Implicitly “Engaging”, Whereas Contemporary Façades are Not Urban Science doi: 10.3390/urbansci4020026 Authors: Nikos A. Salingaros Ann Sussman The human brain evolved to implicitly approach or avoid objects in its surroundings. Requisite for survival, this behavior happens without conscious awareness or control, honed over 60 million years of primate...
Mon May 18, 2020 03:00
Vaccines, Vol. 8, Pages 235: Experimental PCEP-Adjuvanted Swine Influenza H1N1 Vaccine Induced Strong Immune Responses but Did Not Protect Piglets against Heterologous H3N2 Virus Challenge Vaccines doi: 10.3390/vaccines8020235 Authors: Royford Bundi Magiri Ken John Lai George Kiremu Mutwiri Heather Lynne Wilson Vaccination is the most efficient method of protection against influenza infections. However, the rapidly mutating viruses and development of new strains make it necessary...
Mon May 18, 2020 03:00
Vaccines, Vol. 8, Pages 234: A Pool of Eight Virally Vectored African Swine Fever Antigens Protect Pigs Against Fatal Disease Vaccines doi: 10.3390/vaccines8020234 Authors: Lynnette C. Goatley Ana Luisa Reis Raquel Portugal Hannah Goldswain Gareth L. Shimmon Zoe Hargreaves Chak-Sum Ho María Montoya Pedro J. Sánchez-Cordón Geraldine Taylor Linda K. Dixon Christopher L. Netherton Classical approaches to African swine fever virus (ASFV) vaccine development...
Mon May 18, 2020 03:00
Vaccines, Vol. 8, Pages 233: Impact of Switch Options on the Economics of Pneumococcal Conjugate Vaccine (PCV) Introduction in Indonesia Vaccines doi: 10.3390/vaccines8020233 Authors: Auliya A. Suwantika Neily Zakiyah Arif S. W. Kusuma Rizky Abdulah Maarten J. Postma As one of Gavi, the Vaccine Alliance (previously the Global Alliance for Vaccines and Immunization), graduating countries, Indonesia is still eligible to access Gavi price for PCV13, PCV10 A and B. This study...
Mon May 18, 2020 03:00
Vaccines, Vol. 8, Pages 231: A Single Shot Pre-fusion-Stabilized Bovine RSV F Vaccine is Safe and Effective in Newborn Calves with Maternally Derived Antibodies Vaccines doi: 10.3390/vaccines8020231 Authors: Sabine Riffault Sara Hägglund Efrain Guzman Katarina Näslund Luc Jouneau Catherine Dubuquoy Vincent Pietralunga Daphné Laubreton Olivier Boulesteix David Gauthier Aude Remot Abdelhak Boukaridi Alexander Falk Ganna Shevchenko Sara Bergström Lind...
Mon May 18, 2020 03:00
Vaccines, Vol. 8, Pages 232: Vaccine-Induced Adverse Effects in Cultured Neuroblastoma 2A (N2A) Cells Duplicate Toxicity of Serum from Patients with Gulf War Illness (GWI) and Are Prevented in the Presence of Specific Anti-Vaccine Antibodies Vaccines doi: 10.3390/vaccines8020232 Authors: Effie-Photini C. Tsilibary Eric P. Souto Marian Kratzke Lisa M. James Brian E. Engdahl Apostolos P. Georgopoulos Gulf War illness (GWI) is a chronic disease of unknown etiology affecting...
Mon May 18, 2020 03:00
Vaccines, Vol. 8, Pages 230: Herpes Simplex Viruses Whose Replication Can Be Deliberately Controlled as Candidate Vaccines Vaccines doi: 10.3390/vaccines8020230 Authors: Richard Voellmy David C Bloom Nuria Vilaboa Over the last few years, we have been evaluating a novel paradigm for immunization using viruses or virus-based vectors. Safety is provided not by attenuation or inactivation of vaccine viruses, but by the introduction into the viral genomes of genetic mechanisms that...
Mon May 18, 2020 03:00
Vaccines, Vol. 8, Pages 229: A Nanoparticle-Poly(I:C) Combination Adjuvant Enhances the Breadth of the Immune Response to Inactivated Influenza Virus Vaccine in Pigs Vaccines doi: 10.3390/vaccines8020229 Authors: Sankar Renu Ninoshkaly Feliciano-Ruiz Fangjia Lu Shristi Ghimire Yi Han Jennifer Schrock Santosh Dhakal Veerupaxagouda Patil Steven Krakowka Harm HogenEsch Gourapura J. Renukaradhya Intranasal vaccination elicits secretory IgA (SIgA) antibodies...
Mon May 18, 2020 03:00
Viruses, Vol. 12, Pages 557: Ethanol Extract of Caesalpinia Decapetala Inhibits Influenza Virus Infection In Vitro and In Vivo Viruses doi: 10.3390/v12050557 Authors: Li Zhang Jungang Chen Chang Ke Haiwei Zhang Shoujun Zhang Wei Tang Chunlan Liu Ge Liu Si Chen Ao Hu Wenyu Sun Yu Xiao Minli Liu Xulin Chen Influenza virus infections can lead to viral pneumonia and acute respiratory distress syndrome in severe cases, causing significant morbidity and...
Mon May 18, 2020 03:00
Viruses, Vol. 12, Pages 556: External Quality Assessment Program for Next-Generation Sequencing-Based HIV Drug Resistance Testing: Logistical Considerations Viruses doi: 10.3390/v12050556 Authors: Hezhao Ji Neil Parkin Feng Gao Thomas Denny Cheryl Jennings Paul Sandstrom Rami Kantor Next-generation sequencing (NGS) is likely to become the new standard method for HIV drug resistance (HIVDR) genotyping. Despite the significant advances in the development of wet-lab protocols...
Mon May 18, 2020 03:00
Viruses, Vol. 12, Pages 558: Administration of Defective Virus Inhibits Dengue Transmission into Mosquitoes Viruses doi: 10.3390/v12050558 Authors: Tarunendu Mapder John Aaskov Kevin Burrage The host-vector shuttle and the bottleneck in dengue transmission is a significant aspect with regard to the study of dengue outbreaks. As mosquitoes require 100–1000 times more virus to become infected than human, the transmission of dengue virus from human to mosquito is a vulnerability...
Mon May 18, 2020 03:00
Viruses, Vol. 12, Pages 559: Efficacy of Lytic Phage Cocktails on Staphylococcus aureus and Pseudomonas aeruginosa in Mixed-Species Planktonic Cultures and Biofilms Viruses doi: 10.3390/v12050559 Authors: Legesse Garedew Kifelew Morgyn S. Warner Sandra Morales Nicky Thomas David L. Gordon James G. Mitchell Peter G. Speck The efficacy of phages in multispecies infections has been poorly examined. The in vitro lytic efficacies of phage cocktails AB-SA01, AB-PA01, which...
Mon May 18, 2020 03:00
Viruses, Vol. 12, Pages 555: HIV-1 Proviral Transcription and Latency in the New Era Viruses doi: 10.3390/v12050555 Authors: Shukla Ramirez D’Orso Three decades of extensive work in the HIV field have revealed key viral and host cell factors controlling proviral transcription. Various models of transcriptional regulation have emerged based on the collective information from in vitro assays and work in both immortalized and primary cell-based models. Here, we provide a recount...
Mon May 18, 2020 03:00
Viruses, Vol. 12, Pages 554: Serological Immunity to Smallpox in New South Wales, Australia Viruses doi: 10.3390/v12050554 Authors: Valentina Costantino Mallory J. Trent John S. Sullivan Mohana P. Kunasekaran Richard Gray Raina MacIntyre The re-emergence of smallpox is an increasing and legitimate concern due to advances in synthetic biology. Vaccination programs against smallpox using the vaccinia virus vaccine ceased with the eradication of smallpox and, unlike many...
Mon May 18, 2020 03:00
Viruses, Vol. 12, Pages 553: Seroprevalence of Dromedary Camel HEV in Domestic and Imported Camels from Saudi Arabia Viruses doi: 10.3390/v12050553 Authors: Sherif Aly El-Kafrawy Ahmed Mohamed Hassan Mai Mohamed El-Daly Ishtiaq Qadri Ahmed Majdi Tolah Tagreed Lafi Al-Subhi Abdulrahman A. Alzahrani Ghaleb A. Alsaaidi Nabeela Al-Abdullah Reham Mohammed Kaki Tian-Cheng Li Esam Ibraheem Azhar Hepatitis E Virus (HEV) imposes a major health concern in areas...
Mon May 18, 2020 03:00
Vision, Vol. 4, Pages 28: No Advantage for Separating Overt and Covert Attention in Visual Search Vision doi: 10.3390/vision4020028 Authors: W. Joseph MacInnes Ómar I. Jóhannesson Andrey Chetverikov Árni Kristjánsson We move our eyes roughly three times every second while searching complex scenes, but covert attention helps to guide where we allocate those overt fixations. Covert attention may be allocated reflexively or voluntarily, and speeds the rate of information processing...
Mon May 18, 2020 03:00
Water, Vol. 12, Pages 1436: Expert Opinion Valuation Method to Quantify Digital Water Metering Benefits Water doi: 10.3390/w12051436 Authors: Ian Monks Rodney Stewart Oz Sahin Robert Keller Samantha Low-Choy Business cases promoting the introduction of digital water metering (DWM) have, to date, focused on a limited number of benefits, especially water savings, metering costs, occupational health and safety (OHS), and deferral of capital works. An earlier study by the authors...
Mon May 18, 2020 03:00
Water, Vol. 12, Pages 1435: Spatial and Temporal Dynamics of Water Hyacinth and Its Linkage with Lake-Level Fluctuation: Lake Tana, a Sub-Humid Region of the Ethiopian Highlands Water doi: 10.3390/w12051435 Authors: Minychl G. Dersseh Seifu A. Tilahun Abeyou W. Worqlul Mamaru A. Moges Wubneh B. Abebe Demesew A. Mihret Assefa M. Melesse Water hyacinth originated from the Amazon Basin and has expanded to other parts of the world since the 1800s. In Ethiopia, the weed...
Mon May 18, 2020 03:00
Water, Vol. 12, Pages 1432: Identifying Capabilities and Potentials of System Dynamics in Hydrology and Water Resources as a Promising Modeling Approach for Water Management Water doi: 10.3390/w12051432 Authors: Ahmed F. Mashaly Alexander G. Fernald Agriculture is the most important sector with regard to water resources management due to its social, economic, hydrological, and environmental aspects, and many scholars and researchers have been driven to investigate the dynamic interrelationships...
Mon May 18, 2020 03:00
Water, Vol. 12, Pages 1433: Modelling the Vegetation Response to Climate Changes in the Yarlung Zangbo River Basin Using Random Forest Water doi: 10.3390/w12051433 Authors: Kaige Chi Bo Pang Lizhuang Cui Dingzhi Peng Zhongfan Zhu Gang Zhao Shulan Shi Vegetation coverage variation may influence watershed water balance and water resource availability. Yarlung Zangbo River, the longest river on the Tibetan Plateau, has high spatial heterogeneity in vegetation coverage...
Mon May 18, 2020 03:00
Water, Vol. 12, Pages 1434: Summer Changes in Water Mass Characteristics and Vertical Thermohaline Structure in the Eastern Chukchi Sea, 1974–2017 Water doi: 10.3390/w12051434 Authors: Yayu Yang Xuezhi Bai Hydrographic data from the World Ocean Database 2013 and the Chinese National Arctic Research Expedition were used to investigate the summertime changes in the eastern Chukchi Sea from 1974 to 2017. Owing to the Pacific inflow and timing of the sea ice retreat, water masses and...
Mon May 18, 2020 03:00
Water, Vol. 12, Pages 1431: Towards the Implementation of Circular Economy in the Wastewater Sector: Challenges and Opportunities Water doi: 10.3390/w12051431 Authors: Sonia Guerra-Rodríguez Paula Oulego Encarnación Rodríguez Devendra Narain Singh Jorge Rodríguez-Chueca The advancement of science has facilitated increase in the human lifespan, reflected in economic and population growth, which unfortunately leads to increased exploitation of resources. This situation entails...
Mon May 18, 2020 03:00
Water, Vol. 12, Pages 1430: Correction: Usman, M., et al. Performance Evaluation of Small Sized Powdered Ferric Hydroxide as Arsenic Adsorbent. Water 2018, 10, 957 Water doi: 10.3390/w12051430 Authors: Muhammad Usman Ioannis Katsoyiannis Manassis Mitrakas Anastasios Zouboulis Mathias Ernst The authors wish to make the following corrections to this paper [...]
Mon May 18, 2020 03:00
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