JCM, Vol. 9, Pages 1520: Does Motor Cortex Engagement During Movement Preparation Differentially Inhibit Nociceptive Processing in Patients with Chronic Whiplash Associated Disorders, Chronic Fatigue Syndrome and Healthy Controls? An Experimental Study Journal of Clinical Medicine doi: 10.3390/jcm9051520 Authors: Lisa Goudman André Mouraux Liesbeth Daenen Jo Nijs Patrick Cras Nathalie Roussel Maarten Moens Dorine Lenoir Iris Coppieters Eva Huysmans Margot De Kooning...
Mon May 18, 2020 03:00
JCM, Vol. 9, Pages 1521: SARS-CoV-2 in Pregnancy: A Comprehensive Summary of Current Guidelines Journal of Clinical Medicine doi: 10.3390/jcm9051521 Authors: Narang Ibirogba Elrefaei Trad Theiler Nomura Picone Kilby Escuriet Suy Carreras Tonni Ruano Since the declaration of the global pandemic of COVID-19 by the World Health Organization on 11 March 2020, we have continued to see a steady rise in the number of patients infected by SARS-CoV-2....
Mon May 18, 2020 03:00
JCM, Vol. 9, Pages 1519: The Role of the CYP11B2 Promoter Polymorphism in the Diagnosis of Primary Aldosteronism Journal of Clinical Medicine doi: 10.3390/jcm9051519 Authors: Łukasz Żukowski Natalia Wawrusiewicz-Kurylonek Piotr Szumowski Małgorzata Mojsak Saeid Abdelrazek Janusz Myśliwiec Background: nowadays, primary aldosteronism (PA) is suggested to be the most frequent cause of secondary hypertension and it reaches 10% of whole hypertensive population. The CYP11B2...
Mon May 18, 2020 03:00
JCM, Vol. 9, Pages 1513: Location First: Targeting Acute Myeloid Leukemia Within Its Niche Journal of Clinical Medicine doi: 10.3390/jcm9051513 Authors: Pievani Biondi Tomasoni Biondi Serafini Despite extensive research and development of new treatments, acute myeloid leukemia (AML)-backbone therapy has remained essentially unchanged over the last decades and is frequently associated with poor outcomes. Eradicating the leukemic stem cells (LSCs) is the ultimate challenge...
Mon May 18, 2020 03:00
JCM, Vol. 9, Pages 1517: Chagas Disease: Detection of Trypanosoma cruzi by a New, High-Specific Real Time PCR Journal of Clinical Medicine doi: 10.3390/jcm9051517 Authors: Kann Kunz Hansen Sievertsen Crespo Loperena Arriens Dandekar Background: Chagas disease (CD) is a major burden in Latin America, expanding also to non-endemic countries. A gold standard to detect the CD causing pathogen Trypanosoma cruzi is currently not available. Existing real time polymerase...
Mon May 18, 2020 03:00
JCM, Vol. 9, Pages 1516: Mesenchymal Stem/Stromal Cells in Immunity and Disease: A Better Understanding for an Improved Use Journal of Clinical Medicine doi: 10.3390/jcm9051516 Authors: Merimi Lagneaux Agha Lewalle Meuleman Burny Fahmi Najar In this Special Issue, directed and supervised by Dr. Mehdi Najar, a collection of basic research articles and reviews, on the state of the art of Mesenchymal Stem/Stromal Cells (MSCs) immune biology, is presented. Among...
Mon May 18, 2020 03:00
JCM, Vol. 9, Pages 1515: Point-of-Care Diagnostic Tests for Detecting SARS-CoV-2 Antibodies: A Systematic Review and Meta-Analysis of Real-World Data Journal of Clinical Medicine doi: 10.3390/jcm9051515 Authors: Matteo Riccò Pietro Ferraro Giovanni Gualerzi Silvia Ranzieri Brandon Michael Henry Younes Ben Said Natalia Valeryevna Pyatigorskaya Elena Nevolina Jianhong Wu Nicola Luigi Bragazzi Carlo Signorelli SARS-CoV-2 is responsible for a highly contagious...
Mon May 18, 2020 03:00
JCM, Vol. 9, Pages 1518: Neuroimaging of Pediatric Intracerebral Hemorrhage Journal of Clinical Medicine doi: 10.3390/jcm9051518 Authors: Peter B. Sporns Marios-Nikos Psychogios Heather J. Fullerton Sarah Lee Olivier Naggara Grégoire Boulouis Hemorrhagic strokes account for half of all strokes seen in children, and the etiologies of these hemorrhagic strokes differ greatly from those seen in adult patients. This review gives an overview about incidence and etiologies as...
Mon May 18, 2020 03:00
JCM, Vol. 9, Pages 1514: Intensive Care Risk Estimation in COVID-19 Pneumonia Based on Clinical and Imaging Parameters: Experiences from the Munich Cohort Journal of Clinical Medicine doi: 10.3390/jcm9051514 Authors: Egon Burian Friederike Jungmann Georgios A. Kaissis Fabian K. Lohöfer Christoph D. Spinner Tobias Lahmer Matthias Treiber Michael Dommasch Gerhard Schneider Fabian Geisler Wolfgang Huber Ulrike Protzer Roland M. Schmid Markus Schwaiger Marcus...
Mon May 18, 2020 03:00
JCM, Vol. 9, Pages 1512: Decline in Carbon Monoxide Transfer Coefficient in Chronic Obstructive Pulmonary Disease Journal of Clinical Medicine doi: 10.3390/jcm9051512 Authors: Yeon Wook Kim Chang-Hoon Lee Hun-Gyu Hwang Yu-Il Kim Deog-Kyeom Kim Yeon-Mok Oh Sang Haak Lee Ki Uk Kim Sang-Do Lee Background: Although a reduced carbon monoxide transfer coefficient (Kco) is an important feature in chronic obstructive pulmonary disease (COPD), how it changes over time...
Mon May 18, 2020 03:00
JoF, Vol. 6, Pages 66: Encochleated Amphotericin B: Is the Oral Availability of Amphotericin B Finally Reached? Journal of Fungi doi: 10.3390/jof6020066 Authors: Aigner Lass-Flörl As the oldest and for many decades the only available agent for the treatment of life-threatening invasive fungal diseases, amphotericin B (AmB) is known for its broad-spectrum fungicidal activity against a wide range of yeasts and molds. However, the main drawback of the present formulations remains its...
Mon May 18, 2020 03:00
JoF, Vol. 6, Pages 65: Antifungal Activity of Antimicrobial Peptides and Proteins against Aspergillus fumigatus Journal of Fungi doi: 10.3390/jof6020065 Authors: Eloise Ballard Raif Yucel Willem J. G. Melchers Alistair J. P. Brown Paul E. Verweij Adilia Warris Antimicrobial peptides and proteins (AMPs) provide an important line of defence against invading microorganisms. However, the activity of AMPs against the human fungal pathogen Aspergillus fumigatus remains poorly...
Mon May 18, 2020 03:00
J. Imaging, Vol. 6, Pages 34: Multilevel Analysis of the Influence of Maternal Smoking and Alcohol Consumption on the Facial Shape of English Adolescents Journal of Imaging doi: 10.3390/jimaging6050034 Authors: Jennifer Galloway Damian J.J. Farnell Stephen Richmond Alexei I. Zhurov This cross-sectional study aims to assess the influence of maternal smoking and alcohol consumption during pregnancy on the facial shape of non-syndromic English adolescents and demonstrate the potential...
Mon May 18, 2020 03:00
J. Imaging, Vol. 6, Pages 33: Subpixel Localization of Isolated Edges and Streaks in Digital Images Journal of Imaging doi: 10.3390/jimaging6050033 Authors: Devin T. Renshaw John A. Christian Many modern sensing systems rely on the accurate extraction of measurement data from digital images. The localization of edges and streaks in digital images is an important example of this type of measurement, with these techniques appearing in many image processing pipelines. Several approaches...
Mon May 18, 2020 03:00
Life, Vol. 10, Pages 69: The Therapeutic Effectiveness of Full Spectrum Hemp Oil Using a Chronic Neuropathic Pain Model Life doi: 10.3390/life10050069 Authors: Jacob M. Vigil Marena A. Montera Nathan S. Pentkowski Jegason P. Diviant Joaquin Orozco Anthony L. Ortiz Lawrence J. Rael Karin N. Westlund Background: Few models exist that can control for placebo and expectancy effects commonly observed in clinical trials measuring ‘Cannabis’ pharmacodynamics....
Mon May 18, 2020 03:00
Life, Vol. 10, Pages 70: Subtypes of Depression: Latent Class Analysis in Spanish Old People with Depressive Symptoms Life doi: 10.3390/life10050070 Authors: Pérez-Belmonte Galiana Sancho Oliver Tomás Major depressive disorder (MDD) is one of the most disabling disorders and the one that most contributes to disability. When it occurs in older people, it is an additional burden to their potential physical and cognitive deficiencies, making MDD an important public health...
Mon May 18, 2020 03:00
Medicina, Vol. 56, Pages 240: Sepsis Associated Delirium Medicina doi: 10.3390/medicina56050240 Authors: Atterton Paulino Povoa Martin-Loeches Sepsis is a potentially life-threatening condition caused by a systemic dysregulated host response to infection. The brain is particularly susceptible to the effects of sepsis with clinical manifestations ranging from mild confusion to a deep comatose state. Sepsis-associated delirium (SAD) is a cerebral manifestation commonly occurring...
Mon May 18, 2020 03:00
Medicina, Vol. 56, Pages 241: The Aerodynamics and Energy Cost Assessment of an Able-Bodied Cyclist and Amputated Models by Computer Fluid Dynamics Medicina doi: 10.3390/medicina56050241 Authors: Forte Marinho Silveira Barbosa Morais Background and Objectives: The aim of this study was to assess and compare the drag and energy cost of three cyclists assessed by computational fluid dynamics (CFD) and analytical procedures. Materials and methods: A transradial (Tr) and...
Mon May 18, 2020 03:00
Membranes, Vol. 10, Pages 103: Aquaporin-Containing Proteopolymersomes in Polyelectrolyte Multilayer Membranes Membranes doi: 10.3390/membranes10050103 Authors: Reurink Du Górecki Roesink de Vos The field of membranes saw huge developments in the last decades with the introduction of both polyelectrolyte multilayer (PEM)-based membranes and biomimetic membranes. In this work, we combine these two promising systems and demonstrate that proteopolymersomes (PP+) with the...
Mon May 18, 2020 03:00
Membranes, Vol. 10, Pages 104: Simple Flow-Based System with an In-Line Membrane Gas–liquid Separation Unit and a Contactless Conductivity Detector for the Direct Determination of Sulfite in Clear and Turbid Food Samples Membranes doi: 10.3390/membranes10050104 Authors: Ayuning Tyas Sonsa-ard Uraisin Nacapricha Saetear This study presents a simple flow-based system for the determination of the preservative agent sulfite in food and beverages. The standard method of conversion...
Mon May 18, 2020 03:00
Metabolites, Vol. 10, Pages 206: Cross-Omics: Integrating Genomics with Metabolomics in Clinical Diagnostics Metabolites doi: 10.3390/metabo10050206 Authors: Marten H. P. M. Kerkhofs Hanneke A. Haijes A. Marcel Willemsen Koen L. I. van Gassen Maria van der Ham Johan Gerrits Monique G. M. de Sain-van der Velden Hubertus C. M. T. Prinsen Hanneke W. M. van Deutekom Peter M. van Hasselt Nanda M. Verhoeven-Duif Judith J. M. Jans Next-generation sequencing...
Mon May 18, 2020 03:00
Metabolites, Vol. 10, Pages 205: Sedentariness and Urinary Metabolite Profile in Type 2 Diabetic Patients, a Cross-Sectional Study Metabolites doi: 10.3390/metabo10050205 Authors: Benetti Liberto Bressanello Bordano Rosa Miglio Haxhi Pugliese Balducci Cordero Recent findings indicate a significant association between sedentary (SED)-time and type 2 diabetes mellitus(T2DM). The aim of this study was to investigate whether different levels of SED-time...
Mon May 18, 2020 03:00
Microorganisms, Vol. 8, Pages 756: A Selective Serotonin Reuptake Inhibitor, a Proton Pump Inhibitor, and Two Calcium Channel Blockers Inhibit Candida albicans Biofilms Microorganisms doi: 10.3390/microorganisms8050756 Authors: Clarissa J. Nobile Craig L. Ennis Nairi Hartooni Alexander D. Johnson Matthew B. Lohse Biofilms formed by the human fungal pathogen Candida albicans are naturally resistant to many of the antifungal agents commonly used in the clinic. We screened a...
Mon May 18, 2020 03:00
Microorganisms, Vol. 8, Pages 757: Impact of Dietary Manganese on Intestinal Barrier and Inflammatory Response in Broilers Challenged with Salmonella Typhimurium Microorganisms doi: 10.3390/microorganisms8050757 Authors: Zhang Pan Zhang Michiels Zeng Ding Wang Peng Bai Xuan Su Bai Growing concern for public health and food safety has prompted a special interest in developing nutritional strategies for removing waterborne and foodborne pathogens,...
Mon May 18, 2020 03:00
Microorganisms, Vol. 8, Pages 758: Antifungal and Antibiofilm Activities and the Mechanism of Action of Repeating Lysine-Tryptophan Peptides against Candida albicans Microorganisms doi: 10.3390/microorganisms8050758 Authors: Gopal Ramamourthy Jonggwan Park Changho Seo Hans J. Vogel Yoonkyung Park The rapid increase in the emergence of antifungal-resistant Candida albicans strains is becoming a serious health concern. Because antimicrobial peptides (AMPs) may provide a potential...
Mon May 18, 2020 03:00
Microorganisms, Vol. 8, Pages 755: Volatile Compound Screening Using HS-SPME-GC/MS on Saccharomyces eubayanus Strains under Low-Temperature Pilsner Wort Fermentation Microorganisms doi: 10.3390/microorganisms8050755 Authors: Kamila Urbina Pablo Villarreal Roberto F. Nespolo Ricardo Salazar Rocio Santander Francisco A. Cubillos The recent isolation of the yeast Saccharomyces eubayanus has opened new avenues in the brewing industry. Recent studies characterized the production...
Mon May 18, 2020 03:00
Molbank, Vol. 2020, Article M1137: 1-Benzyl-2-(thien-2-yl)-4,5-dihydro-1H-imidazole Molbank doi: 10.3390/M1137 Authors: Alexandra S. Golubenkova Nikita E. Golantsov Alexey A. Festa Leonid G. Voskressensky Imidazolines are a valuable class of organic compounds, namely ligands of imidazoline receptors, chiral ligands for metal catalysis, synthetic intermediates. The title compound has been prepared through a modified procedure, employing N-benzylethylenediamine and thiophene-2-carbaldehyde...
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2356: Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors Molecules doi: 10.3390/molecules25102356 Authors: Oh Rangarajan Chaudhary Singh Singh Singh Tondo Gambacorta Nicolotti Mathew Kim Previously synthesized novel chalcone oxime ethers (COEs) were evaluated for inhibitory activities against monoamine oxidases (MAOs) and acetylcholinesterase (AChE). Twenty-two of the...
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2355: Synthesis and Cytotoxic Activity of Chiral Sulfonamides Based on the 2-azabicycloalkane Skeleton Molecules doi: 10.3390/molecules25102355 Authors: Mahzeiar Samadaei Matthias Pinter Daniel Senfter Sibylle Madlener Nataliya Rohr-Udilova Dominika Iwan Karolina Kamińska Elżbieta Wojaczyńska Jacek Wojaczyński Andrzej Kochel A series of chiral sulfonamides containing the 2-azabicycloalkane scaffold were prepared from aza-Diels–Alder...
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2354: Enzymes, Biocatalysis and Chemical Biology Molecules doi: 10.3390/molecules25102354 Authors: Stefano Serra Chemical transformations that take advantage of biocatalysis are of great interest to chemists [...]
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2353: Sexual Dimorphism in Energy Metabolism of Wistar Rats Using Data Analysis Molecules doi: 10.3390/molecules25102353 Authors: Andrea Leskanicova Olga Chovancova Marian Babincak Ludmila Verboova Zuzana Benetinova Denisa Macekova Jozef Kostolny Benadik Smajda Terezia Kiskova The prevalence of some chronic diseases, such as cancer or neurodegenerative disorders, differs between sexes. Animal models provide an important tool to adopt...
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2352: Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy
Molecules, Vol. 25, Pages 2352: Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy Molecules doi: 10.3390/molecules25102352 Authors: Grégoire Quinet Maria Gonzalez-Santamarta Clara Louche Manuel S. Rodriguez Protein degradation is tightly regulated inside cells because of its utmost importance for protein homeostasis (proteostasis). The two major intracellular proteolytic pathways are the ubiquitin-proteasome and the autophagy-lysosome systems which ensure...
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2346: Bacillus amyloliquefaciens RWL-1 as a New Potential Strain for Augmenting Biochemical and Nutritional Composition of Fermented Soybean Molecules doi: 10.3390/molecules25102346 Authors: Raheem Shahzad Adeeb Shehzad Saqib Bilal In-Jung Lee Soybean (Glycine max L.) is a good source of natural antioxidants and commonly consumed as fermented products such as cheonggukjang, miso, tempeh, and sufu in Asian countries. The aim of the current study was...
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2347: Hypoxia-Activated Prodrug Derivatives of Carbonic Anhydrase Inhibitors in Benzenesulfonamide Series: Synthesis and Biological Evaluation Molecules doi: 10.3390/molecules25102347 Authors: Emilie Anduran Ashok Aspatwar Nanda-Kumar Parvathaneni Dennis Suylen Silvia Bua Alessio Nocentini Seppo Parkkila Claudiu T. Supuran Ludwig Dubois Philippe Lambin Jean-Yves Winum Hypoxia, a common feature of solid tumours’ microenvironment,...
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2350: Antiadipogenic Effects of Mixtures of Cornus officinalis and Ribes fasciculatum Extracts on 3T3-L1 Preadipocytes and High-Fat Diet-Induced Mice Molecules doi: 10.3390/molecules25102350 Authors: Eunkuk Park Chang Gun Lee Hyesoo Jeong Subin Yeo Ji Ae Kim Seon-Yong Jeong Medicinal plants have been used worldwide as primary alternative healthcare supplements. Cornus officinalis (CO) and Ribes fasciculatum (RF) are traditional medicinal plants...
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2351: Glycomacropeptide Ameliorates Indomethacin-Induced Enteropathy in Rats by Modifying Intestinal Inflammation and Oxidative Stress Molecules doi: 10.3390/molecules25102351 Authors: Daniel Cervantes-García Armida I. Bahena-Delgado Mariela Jiménez Laura E. Córdova-Dávalos Vanessa Ruiz-Esparza Palacios Esperanza Sánchez-Alemán María C. Martínez-Saldaña Eva Salinas Nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy is considered...
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2349: Synthesis of Novel 3,6-Dithienyl Diketopyrrolopyrrole Dyes by Direct C‒H Arylation Molecules doi: 10.3390/molecules25102349 Authors: Amsalu Efrem Yemene Vishwesh Venkatraman David Moe Almenningen Bård Helge Hoff Odd Reidar Gautun Direct C‒H arylation coupling is potentially a more economical and sustainable process than conventional cross-coupling. However, this method has found limited application in the synthesis of organic dyes for dye‒sensitized...
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2348: Potential Plasticity of the Mannoprotein Repertoire Associated to Mycobacterium tuberculosis Virulence Unveiled by Mass Spectrometry-Based Glycoproteomics Molecules doi: 10.3390/molecules25102348 Authors: Laure Tonini Bashir Sadet Alexandre Stella David Bouyssié Jérôme Nigou Odile Burlet-Schiltz Michel Rivière To date, Mycobacterium tuberculosis (Mtb) remains the world’s greatest infectious killer. The rise of multidrug-resistant...
Mon May 18, 2020 03:00
Molecules, Vol. 25, Pages 2345: New Strategies in the Cultivation of Olive Trees and Repercussions on the Nutritional Value of the Extra Virgin Olive Oil Molecules doi: 10.3390/molecules25102345 Authors: Irene Dini Giulia Graziani Anna Gaspari Francesca Luisa Fedele Andrea Sicari Francesco Vinale Pierpaolo Cavallo Matteo Lorito Alberto Ritieni The health advantages of extra-virgin olive oil (EVOO) are ascribed mainly to the antioxidant ability of the phenolic...
Mon May 18, 2020 03:00
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