Cells, Vol. 9, Pages 1249: A New Pathway Promotes Adaptation of Human Glioblastoma Cells to Glucose Starvation Cells doi: 10.3390/cells9051249 Authors: Azzalin Brambilla Arbustini Basello Speciani Mauri Bezzi Magrassi Adaptation of glioblastoma to caloric restriction induces compensatory changes in tumor metabolism that are incompletely known. Here we show that in human glioblastoma cells maintained in exhausted medium, SHC adaptor protein 3 (SHC3) increases...
Cells, Vol. 9, Pages 1248: Blood Eosinophils Subtypes and Their Survivability in Asthma Patients Cells doi: 10.3390/cells9051248 Authors: Januskevicius Jurkeviciute Janulaityte Kalinauskaite-Zukauske Miliauskas Malakauskas Eosinophils subtypes as lung-resident (rEOS) and inflammatory (iEOS) eosinophils are different in surface protein expression, functions, response to IL-5 and localization in lungs. rEOS- and iEOS-like eosinophils are found in blood; thus, we aimed...
Cells, Vol. 9, Pages 1247: Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism Cells doi: 10.3390/cells9051247 Authors: Charlotte Lefort Martin Roumain Matthias Van Hul Marialetizia Rastelli Rita Manco Isabelle Leclercq Nathalie M. Delzenne Vincenzo Di Marzo Nicolas Flamand Serge Luquet Cristoforo Silvestri Giulio G. Muccioli Patrice D. Cani Diverse metabolic disorders have been associated with an alteration of N-acylethanolamine (NAE) levels....
Cells, Vol. 9, Pages 1246: Allogeneic ADSCs Induce the Production of Alloreactive Memory-CD8 T Cells through HLA-ABC Antigens Cells doi: 10.3390/cells9051246 Authors: Sung-Ho Chang Hyun Je Kim Chung-Gyu Park We investigated the immunogenicity of allogeneic human adipose-derived mesenchymal stem cells (ADSCs) through the production of alloreactive-CD8 T and -memory CD8 T cells, based on their human leukocyte antigen (HLA) expression. In surface antigen analysis, ADSCs do not express...
Cells, Vol. 9, Pages 1242: The Detrimental Action of Adenosine on Glutamate-Induced Cytotoxicity in PC12 Cells Can Be Shifted towards a Neuroprotective Role through A1AR Positive Allosteric Modulation Cells doi: 10.3390/cells9051242 Authors: Fabrizio Vincenzi Silvia Pasquini Stefania Gessi Stefania Merighi Romeo Romagnoli Pier Andrea Borea Katia Varani Glutamate cytotoxicity is implicated in neuronal death in different neurological disorders including stroke, traumatic...
Cells, Vol. 9, Pages 1245: Glial A2B Adenosine Receptors Modulate Abnormal Tachykininergic Responses and Prevent Enteric Inflammation Associated with High Fat Diet-Induced Obesity Cells doi: 10.3390/cells9051245 Authors: D'Antongiovanni Benvenuti Fornai Pellegrini van den Wijngaard Cerantola Giron Caputi Colucci Haskó Németh Blandizzi Antonioli The role played by adenosine A2B receptors (A2BRs) in the regulation of enteric glial cell (EGC)...
Cells, Vol. 9, Pages 1244: The Forebrain-Specific Overexpression of Acid Sphingomyelinase Induces Depressive-Like Symptoms in Mice Cells doi: 10.3390/cells9051244 Authors: Zoicas Schumacher Kleuser Reichel Gulbins Fejtova Kornhuber Rhein Human and murine studies identified the lysosomal enzyme acid sphingomyelinase (ASM) as a target for antidepressant therapy and revealed its role in the pathophysiology of major depression. In this study, we generated a mouse...
Cells, Vol. 9, Pages 1243: Platelet Interactions with Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells Lead to Hepatocyte Proliferation Cells doi: 10.3390/cells9051243 Authors: Jeremy Meyer Alexandre Balaphas Pierre Fontana Philippe Morel Simon C. Robson Karin Sadoul Carmen Gonelle-Gispert Léo Bühler (1) Background: Platelets were postulated to constitute the trigger of liver regeneration. The aim of this study was to dissect the cellular interactions...
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