Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
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To the Editor: We read the work by Xu, et al [1] with great interest and congratulate them for the publication of this large-scale retrospective study. Radiation-induced lymphopenia is an important prognostic factor for esophageal cancers [2,3] and many other solid tumours [4]. The estimation of dose to circulating lymphocytes by adopting the effective dose to immune cells (EDIC) formula is gaining external validity in different types of cancers. In stage III non-small cell lung cancer, Ladbury,...
Radiation-associated dysphagia (RAD) is one of the severe sequelae of treatment in head and neck (HNC) cancer patients undergoing radiation therapy (RT), with chronic toxicity arising even after acute symptoms have ceased [1]. Chronic RAD is even more relevant in the era of Human Papillomavirus associated (HPV) HNC, where the majority of patients have curable disease with prolonged survival, and thereby endure later toxicities which are otherwise not encountered in patients with aggressive HPV negative...
Esophageal cancer is the eighth most common cancer worldwide with an estimated annual incidence and mortality above 572,000 and 508,000, respectively [1]. This makes it the sixth leading cause for cancer-related mortality [2]. Its five-year survival rate is estimated to be as low as 14% [3] and patients with metastatic disease have a median survival of less than one year if treated with chemotherapy [4].
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Analytical ChemistryDOI: 10.1021/acs.analchem.0c01200
[ASAP] Near-Infrared Electrochemiluminescence Immunoassay with Biocompatible Au Nanoclusters as Tags
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00125
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Analytical ChemistryDOI: 10.1021/acs.analchem.0c00014
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: Approximately 2% of the population are anticoagulated and over 50% of over 65-year-olds are prescribed antiplatelet agents. Several systematic reviews have shown the safety of interrupting anticoagulation and antiplatelets for non-emergency surgery, although such reviews excluded upper limb procedures and represents the rationale for this review.
: Vascularised composite allotransplantation (VCA) permits like-for-like reconstruction following extensive soft tissue injuries. The initial management of extensive soft tissue injury can lead to the development of anti-HLA antibodies through injury-related factors, transfusion and cadaveric grafting. The role of antibody-mediated rejection, donor-specific antibody formation and graft rejection in the context of VCA remains unclear. This systematic review aimed to determine whether pre-transplant...
Although end-to-side anastomosis is an essential method for the transfer of free flaps in traumatic extremity injuries, orthoplastic surgeons have no standard technique for performing this procedure. We describe a simple and reliable end-to-side technique is modified from that commonly used by cardiovascular surgeons for free-flap transfer.
Feasibility Study on Equine Acellular Pericardium Matrix (APM): A New Tool for Breast Reconstruction
The advent of acellular dermal matrix (ADM) for lower pole coverage allows immediate reconstructions with improved aesthetic outcomes and faster recovery. This study describes for the first time the use of a new acellular pericardium matrix (APM) in implant-based breast reconstruction and characterises its safety profile. Equity is a membrane with a natural cross-linked structure with many of the properties of ADMs but improved resistance and reduced thickness. A retrospective data collection of...
: The profunda femoris artery perforator (PAP) flap is gaining popularity in microsurgical reconstruction. The complications that can occur after the PAP flap harvest include donor-site lymphedema, seroma, or cellulitis. The aim of this study was to evaluate and establish a safer technique for the elevation of lymphatic vessels preserving profunda femoris artery perforator (LpPAP) flap using pre- and intraoperative ICG lymphography. In this article, we also evaluate the anatomical relationship between...
To date, surgical delay of skin flaps is the most common and reliable method that increases skin flap survival. In this study, we aimed to increase skin flap viability using preconditioning by microneedling. Seventy-two Sprague Dawley rats were randomly divided into control, surgical flap delay (SFD) and four microneedling groups (seven or 14 days of preconditioning with 0.5 or 1 mm needles). Modified McFarlane flaps were raised on the back of the rats. In Group I, a caudal pedicled skin flap was...
Previous experiments using our in vivo tissue-engineering chamber (TEC) model demonstrated that adipose flap was spontaneously generated without the need for adipocyte or stem cell implantation. The purposes of the present study were to clarify 1) the reproducibility of this method to create adipose flaps 2) the time-course of adipogenesis and 3) the long-term stability of the adipose flap generated.
To study the safety and tolerability of Lymfactin® treatment combined with microvascular lymph node transfer surgery in patients with upper limb lymphedema.
We read with great interest the article titled “Infraorbital groove correction by microfat injection after lower blepharoplasty” by Won Lee et al.1 The authors described a new interesting technique, involving the use of autologous fat from periorbital compartments, for infraorbital groove correction after lower blepharoplasty, with the main advantage of correction the deep infraorbital groove and subsequently rejuvenating the lower eyelid area without the need for further fat tissue donor area.
We thank Dr. Wen-Tsao Ho for an astute description of our study. As we described in our article, fat transposition and grafting are useful for filling the infraorbital groove.1 Fat pad sliding involves shifting the medial orbital fat normally excised in lower blepharoplasty,2 and naturally, central fat pad sliding can also be performed at the centre of the infraorbital groove. However, as we described in our article, fat pad sliding sometimes results in undercorrection. Infraorbital grooves are not...
Summary: Laparoscopic harvest method to obtain gastro-epiploic lymph node flaps for lymphedema treatment has been previously described. In this article, the technical details of an alternative method -open approach via mini-laparotomy incision- for harvesting gastro-epiploic lymph node flaps and preparation of the flaps for the inset is presented. A total of 17 patients were included in this series of the mini-laparotomy approach. Blood loss was minimal during the surgery. The average duration of...
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