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Δευτέρα 18 Μαΐου 2020


Host circulating biomarkers for immune-checkpoint inhibitors: single-agent and combinations
Future Oncology, Ahead of Print.
Future Oncology
Mon May 18, 2020 12:33
Risk factors for developing cardiac toxicities in cancer patients treated with panitumumab combination therapy
Future Oncology, Ahead of Print.
Future Oncology
Mon May 18, 2020 12:27
Leukocyte telomere length and hTERT genetic polymorphism rs2735940 influence the renal cell carcinoma clinical outcome
Future Oncology, Ahead of Print.
Future Oncology
Mon May 18, 2020 12:03
Metastatic propagation of thyroid cancer; organ tropism and major modulators
Future Oncology, Ahead of Print.
Future Oncology
Mon May 18, 2020 11:28
Outcomes of retreatment with anti-PD-1 monotherapy after response to first course in patients with cutaneous melanoma
Future Oncology, Ahead of Print.
Future Oncology
Fri May 15, 2020 14:13
Combination treatments with immunotherapy in brain metastases patients
Future Oncology, Ahead of Print.
Future Oncology
Fri May 15, 2020 10:42
Pancreatic cancer in Australia: is not it time we address the inequitable resource problem?
Future Oncology, Ahead of Print.
Future Oncology
Fri May 15, 2020 10:16
The management of patients with metastatic prostate cancer during the COVID-19 pandemic
Future Oncology, Ahead of Print.
Future Oncology
Fri May 15, 2020 05:55
The impact of the effective dose to immune cells on lymphopenia and survival of esophageal cancer after chemoradiotherapy: Asian perspectives in the immunotherapy era
To the Editor: We read the work by Xu, et al [1] with great interest and congratulate them for the publication of this large-scale retrospective study. Radiation-induced lymphopenia is an important prognostic factor for esophageal cancers [2,3] and many other solid tumours [4]. The estimation of dose to circulating lymphocytes by adopting the effective dose to immune cells (EDIC) formula is gaining external validity in different types of cancers. In stage III non-small cell lung cancer, Ladbury,...
Radiotherapy and Oncology
Mon May 18, 2020 03:00
Precision toxicity correlates of tumor spatial proximity to organs at risk in cancer patients receiving intensity-modulated radiotherapy
Radiation-associated dysphagia (RAD) is one of the severe sequelae of treatment in head and neck (HNC) cancer patients undergoing radiation therapy (RT), with chronic toxicity arising even after acute symptoms have ceased [1]. Chronic RAD is even more relevant in the era of Human Papillomavirus associated (HPV) HNC, where the majority of patients have curable disease with prolonged survival, and thereby endure later toxicities which are otherwise not encountered in patients with aggressive HPV negative...
Radiotherapy and Oncology
Fri May 15, 2020 03:00
Efficacy and safety of stenting and additional oncological treatment versus stenting alone in unresectable esophageal cancer: a meta-analysis and systematic review
Esophageal cancer is the eighth most common cancer worldwide with an estimated annual incidence and mortality above 572,000 and 508,000, respectively [1]. This makes it the sixth leading cause for cancer-related mortality [2]. Its five-year survival rate is estimated to be as low as 14% [3] and patients with metastatic disease have a median survival of less than one year if treated with chemotherapy [4].
Radiotherapy and Oncology
Fri May 15, 2020 03:00
[ASAP] Microfluidic Probe for In-Situ Extraction of Adherent Cancer Cells to Detect Heterogeneity Difference by Electrospray Ionization Mass Spectrometry
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01200
Analytical Chemistry
Mon May 18, 2020 07:00
[ASAP] Near-Infrared Electrochemiluminescence Immunoassay with Biocompatible Au Nanoclusters as Tags
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00125
Analytical Chemistry
Mon May 18, 2020 07:00
[ASAP] Direct Infusion-Three-Dimensional-Mass Spectrometry Enables Rapid Chemome Comparison among Herbal Medicines
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00483
Analytical Chemistry
Mon May 18, 2020 07:00
[ASAP] High-Precision, Gas-Phase Hydrogen/Deuterium-Exchange Kinetics by Mass Spectrometry Enabled by Exchange Standards
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00749
Analytical Chemistry
Mon May 18, 2020 07:00
[ASAP] Metal-Assisted Protein Quantitation (MAPq): Multiplex Analysis of Protein Expression Using Lanthanide-Modified Antibodies with Detection by Inductively Coupled Plasma Mass Spectrometry
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00058
Analytical Chemistry
Mon May 18, 2020 07:00
[ASAP] Correction to Shifting-Nitroxides to Investigate Enzymatic Hydrolysis of Fatty Acids by Lipases Using Electron Paramagnetic Resonance in Turbid Media
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01833
Analytical Chemistry
Mon May 18, 2020 07:00
[ASAP] Electrochemical Cloth-Based DNA Sensors (ECDSs): A New Class of Electrochemical Gene Sensors
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00669
Analytical Chemistry
Mon May 18, 2020 07:00
[ASAP] Solid-Contact Ion-Selective and Reference Electrodes Covalently Attached to Functionalized Poly(ethylene terephthalate)
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00296
Analytical Chemistry
Mon May 18, 2020 07:00
[ASAP] Electrochemical Micropyramid Array-Based Sensor for <italic toggle="yes">In Situ</italic> Monitoring of Dopamine Released from Neuroblastoma Cells
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00835
Analytical Chemistry
Mon May 18, 2020 07:00
[ASAP] Novel Position-Specific <sup>18</sup>O/<sup>16</sup>O Measurement of Carbohydrates. II. The Complete Intramolecular <sup>18</sup>O/<sup>16</sup>O Profile of the Glucose Unit in a Starch of C4 Origin
Analytical ChemistryDOI: 10.1021/acs.analchem.9b05314
Analytical Chemistry
Fri May 15, 2020 07:00
[ASAP] “Switch-On” Fluorescence Detection of Glucose with High Specificity and Sensitivity Based on Silver Nanoparticles Supported on Porphyrin Metal–Organic Frameworks
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01651
Analytical Chemistry
Fri May 15, 2020 07:00
[ASAP] Correction to “Sulfur-Doped Graphene Quantum Dots as a Novel Fluorescent Probe for Highly Selective and Sensitive Detection of Fe<sup>3+</sup>”
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01997
Analytical Chemistry
Fri May 15, 2020 07:00
[ASAP] Absolute Quantitation of Proteins by Coulometric Mass Spectrometry
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01151
Analytical Chemistry
Fri May 15, 2020 07:00
[ASAP] Signaling Aptamer Optimization through Selection Using RNA-Capturing Microsphere Particles
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01338
Analytical Chemistry
Fri May 15, 2020 07:00
[ASAP] Glassy Carbon Electrode Electromodification in the Presence of Organic Monomers: Electropolymerization versus Activation
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01337
Analytical Chemistry
Fri May 15, 2020 07:00
[ASAP] Integrated Ultrasonic Aggregation-Induced Enrichment with Raman Enhancement for Ultrasensitive and Rapid Biosensing
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01011
Analytical Chemistry
Fri May 15, 2020 07:00
[ASAP] Multiplexed Comparative Analysis of Intact Glycopeptides Using Electron-Transfer Dissociation and Synchronous Precursor Selection Based Triple-Stage Mass Spectrometry
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00014
Analytical Chemistry
Thu May 14, 2020 07:00
Hand and Wrist Surgery on Anticoagulants and Antiplatelets: A Systematic Review and Meta-analysis
: Approximately 2% of the population are anticoagulated and over 50% of over 65-year-olds are prescribed antiplatelet agents. Several systematic reviews have shown the safety of interrupting anticoagulation and antiplatelets for non-emergency surgery, although such reviews excluded upper limb procedures and represents the rationale for this review.
Plastic, Reconstructive & Aesthetic Surgery
Mon May 18, 2020 03:00
nPre-transplant Management and Sensitisation in Vascularised Composite Allotransplantation: A Systematic Review
: Vascularised composite allotransplantation (VCA) permits like-for-like reconstruction following extensive soft tissue injuries. The initial management of extensive soft tissue injury can lead to the development of anti-HLA antibodies through injury-related factors, transfusion and cadaveric grafting. The role of antibody-mediated rejection, donor-specific antibody formation and graft rejection in the context of VCA remains unclear. This systematic review aimed to determine whether pre-transplant...
Plastic, Reconstructive & Aesthetic Surgery
Mon May 18, 2020 03:00
Reliable free flaps using the microscopic parachute end-to-side technique in severe extremity injuries
Although end-to-side anastomosis is an essential method for the transfer of free flaps in traumatic extremity injuries, orthoplastic surgeons have no standard technique for performing this procedure. We describe a simple and reliable end-to-side technique is modified from that commonly used by cardiovascular surgeons for free-flap transfer.
Plastic, Reconstructive & Aesthetic Surgery
Mon May 18, 2020 03:00
Feasibility Study on Equine Acellular Pericardium Matrix (APM): A New Tool for Breast Reconstruction
The advent of acellular dermal matrix (ADM) for lower pole coverage allows immediate reconstructions with improved aesthetic outcomes and faster recovery. This study describes for the first time the use of a new acellular pericardium matrix (APM) in implant-based breast reconstruction and characterises its safety profile. Equity is a membrane with a natural cross-linked structure with many of the properties of ADMs but improved resistance and reduced thickness. A retrospective data collection of...
Plastic, Reconstructive & Aesthetic Surgery
Mon May 18, 2020 03:00
An anatomical Study of the Lymph-Collecting Vessels of the Medial Thigh and Clinical Applications of Lymphatic Vessels Preserving Profunda Femoris Artery Perforator (LpPAP) Flap using pre- and intraoperative indocyanine green (ICG) lymphography
: The profunda femoris artery perforator (PAP) flap is gaining popularity in microsurgical reconstruction. The complications that can occur after the PAP flap harvest include donor-site lymphedema, seroma, or cellulitis. The aim of this study was to evaluate and establish a safer technique for the elevation of lymphatic vessels preserving profunda femoris artery perforator (LpPAP) flap using pre- and intraoperative ICG lymphography. In this article, we also evaluate the anatomical relationship between...
Plastic, Reconstructive & Aesthetic Surgery
Mon May 18, 2020 03:00
Effects of Microneedle Length and Duration of Preconditioning on Random Pattern Skin Flaps in Rats
To date, surgical delay of skin flaps is the most common and reliable method that increases skin flap survival. In this study, we aimed to increase skin flap viability using preconditioning by microneedling. Seventy-two Sprague Dawley rats were randomly divided into control, surgical flap delay (SFD) and four microneedling groups (seven or 14 days of preconditioning with 0.5 or 1 mm needles). Modified McFarlane flaps were raised on the back of the rats. In Group I, a caudal pedicled skin flap was...
Plastic, Reconstructive & Aesthetic Surgery
Mon May 18, 2020 03:00
Spontaneously Generated Large Adipose Flaps in in vivo Tissue Engineering Chambers (TECs)
Previous experiments using our in vivo tissue-engineering chamber (TEC) model demonstrated that adipose flap was spontaneously generated without the need for adipocyte or stem cell implantation. The purposes of the present study were to clarify 1) the reproducibility of this method to create adipose flaps 2) the time-course of adipogenesis and 3) the long-term stability of the adipose flap generated.
Plastic, Reconstructive & Aesthetic Surgery
Mon May 18, 2020 03:00
Phase 1 Lymfactin® Study: Short-term Safety of Combined Adenoviral VEGF-C and Lymph Node Transfer Treatment for Upper Extremity Lymphedema
To study the safety and tolerability of Lymfactin® treatment combined with microvascular lymph node transfer surgery in patients with upper limb lymphedema.
Plastic, Reconstructive & Aesthetic Surgery
Mon May 18, 2020 03:00
Infraorbital groove correction by microfat injection after lower blepharoplasty
We read with great interest the article titled “Infraorbital groove correction by microfat injection after lower blepharoplasty” by Won Lee et al.1 The authors described a new interesting technique, involving the use of autologous fat from periorbital compartments, for infraorbital groove correction after lower blepharoplasty, with the main advantage of correction the deep infraorbital groove and subsequently rejuvenating the lower eyelid area without the need for further fat tissue donor area.
Plastic, Reconstructive & Aesthetic Surgery
Sun May 17, 2020 03:00
Reply: Infraorbital groove correction by microfat injection after lower blepharoplasty
We thank Dr. Wen-Tsao Ho for an astute description of our study. As we described in our article, fat transposition and grafting are useful for filling the infraorbital groove.1 Fat pad sliding involves shifting the medial orbital fat normally excised in lower blepharoplasty,2 and naturally, central fat pad sliding can also be performed at the centre of the infraorbital groove. However, as we described in our article, fat pad sliding sometimes results in undercorrection. Infraorbital grooves are not...
Plastic, Reconstructive & Aesthetic Surgery
Sun May 17, 2020 03:00
Technical Details for Harvesting Gastro-Epiploic Lymph Node Flaps via Mini-Laparotomy Incision
Summary: Laparoscopic harvest method to obtain gastro-epiploic lymph node flaps for lymphedema treatment has been previously described. In this article, the technical details of an alternative method -open approach via mini-laparotomy incision- for harvesting gastro-epiploic lymph node flaps and preparation of the flaps for the inset is presented. A total of 17 patients were included in this series of the mini-laparotomy approach. Blood loss was minimal during the surgery. The average duration of...
Plastic, Reconstructive & Aesthetic Surgery
Sun May 17, 2020 03:00

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