Reflectance confocal microscopy and image analysis to evaluate the efficacy of a topical facial serum with 20% vitamin C in improving signs of aging

Vitamin C is known for its antioxidant potential and activity in prevents and reverts signs of aging, also by the collagen biosynthetic pathway. Photoprotective properties of topically applied vitamin C have also been demonstrated, placing this molecule as a potential candidate for use in the prevention and treatment of skin aging. A topically applied serum containing 20% vitamin C in different forms (ascorbic acid, ascorbyl methylsilanol pectinate and ascorbyl glucoside) associated with ferulic acid and Ginkgo biloba extract was tested on healthy female volunteers presenting photoaged skin on face to evaluate clinical efficacy of such treatment.