Mycobacterium marinum infection associated with infliximab therapy in a patient with pulmonary and skin sarcoidosis

Mycobacterium marinum is a nontuberculous acid-fast organism that is an infrequent infection of the skin and soft tissues. The organism is often encountered after exposure to certain fish species and marine environments. High risk patients are those with underlying autoimmune diseases (e.g., sarcoidosis, Crohn's, ankylosing spondylitis) being treated with immunosuppressive therapies such as infliximab and other anti–tumor necrosis factor agents. We present one of the first cases of M. marinum infection associated with infliximab therapy in a patient with pulmonary and skin sarcoidosis.