Case report of aggressive treatments for large-cell neuroendocrine carcinoma of the esophagus.
updated at 15:08 by Nakao Y, Okino T, Yamashita YI, Taki K, Nakagawa S, Matsumoto K, Goto M, Baba H via pubmed: "int j surg case rep...
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Case report of aggressive treatments for large-cell neuroendocrine carcinoma of the esophagus.
Int J Surg Case Rep. 2019 Jun 28;60:291-295
Authors: Nakao Y, Okino T, Yamashita YI, Taki K, Nakagawa S, Matsumoto K, Goto M, Baba H
Abstract
INTRODUCTION: Neuroendocrine carcinoma of the esophagus is a rare and highly aggressive disease, and the biological features are poorly understood.
PRESENTATION OF CASE: We report a case of large-cell neuroendocrine carcinoma of the esophagus in a 73-year-old male patient with aggressive surgical treatment. Upper gastrointestinal endoscopy revealed an esophageal large mass. Histological examination of biopsy specimens indicated a neuroendocrine carcinoma. First, we performed subtotal esophagectomy with lymphadenectomy, but he experienced metastasis at the liver and rib 5 months later. Next, we performed partial hepatectomy and radiotherapy for rib metastasis, but he experienced metastasis at the left pulmonary hilar lymph node and sacral bone. Finally, we performed chemotherapy using cisplatin and irinotecan.
DISCUSSION: The therapeutic strategy for large-cell NEC of the esophagus is unestablished. Thus, accumulating the therapeutic results garnered from various treatment tools is considerably important.
CONCLUSION: Aggressive multimodal treatments including surgery have a possibility to gain better survival in patients with large-cell NEC of the esophagus.
PMID: 31265990 [PubMed - as supplied by publisher]
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Pulmonary metastasis presenting as a ground glass opacity-like lesion with a thin-walled cavity: A case report.
updated at 15:08 by Haro A, Wakasu S, Takada K, Osoegawa A, Kamitani T, Tagawa T, Mori M via pubmed: "int j surg case rep...
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Pulmonary metastasis presenting as a ground glass opacity-like lesion with a thin-walled cavity: A case report.
Int J Surg Case Rep. 2019 Jun 21;60:287-290
Authors: Haro A, Wakasu S, Takada K, Osoegawa A, Kamitani T, Tagawa T, Mori M
Abstract
INTRODUCTION: Most of pulmonary metastases present as well-defined solid and round nodules. Here we report a case of a pulmonary metastasis presenting as a ground glass opacity (GGO)-like lesion with a thin-walled cavity and lymph node metastasis of tongue cancer.
CASE PRESENTAION: A 22-year-old man was referred to our department for surgical diagnosis and treatment for a GGO-like pulmonary nodule with a thin-walled cavity in the right lower lobe. He had a history of surgical resection for tongue cancer. The size of the GGO-like lesion with a thin-walled cavity in the center gradually increased. A right lower lobectomy and hilar lymphadenectomy were performed. Postoperative pathology revealed the lesion as pulmonary metastasis and hilar lymph node metastasis of tongue cancer.
DISCUSSION: Our case report of pulmonary metastasis of tongue cancer is rare from the viewpoint of pulmonary GGO-like lesions with a following thin-walled cavity and hilar lymph node metastasis. The positron emission tomography/computed tomography (PET/CT) examination was useful to show right hilar lymph node metastasis.
CONCLUSION: It is important to make a differential diagnosis of from the pulmonary nodule in case of a GGO-like lesion with a thin-walled cavity.
PMID: 31265989 [PubMed - as supplied by publisher]
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Stomal stenosis during gradual closure of a traumatic abdominal wall hernia.
updated at 15:08 by Suzuki M, Matsushima H, Uehara K, Saiki T, Hayamizu A, Kamisasanuki T, Sugiki D via pubmed: "int j surg case rep...
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Stomal stenosis during gradual closure of a traumatic abdominal wall hernia.
Int J Surg Case Rep. 2019 Jun 16;60:284-286
Authors: Suzuki M, Matsushima H, Uehara K, Saiki T, Hayamizu A, Kamisasanuki T, Sugiki D
Abstract
INTRODUCTION: Traumatic abdominal wall hernias are often accompanied by intra-abdominal injuries, and a stoma may be required. Although rare, stomal stenosis can develop after the repair of a traumatic abdominal wall hernia.
PRESENTATION OF CASE: A 65-year-old woman was in a head-on collision with a truck and was brought by ambulance to our facility. The findings of a physical examination and computed tomography scan suggested bowel perforation for which exploratory surgery was performed. The lacerated small bowel and sigmoid colon were resected and an ileostomy and colostomy were created. Abdominal wall reconstruction was impossible because of the large defect size. Repair of the abdominal wall was achieved by gradual closure of the fascia after surgery in combination with negative pressure wound therapy. Stenosis of the ileostomy occurred during this process and was surgically repaired.
DISCUSSION: We reconstructed the abdominal wall using negative pressure wound therapy in combination with sutures while minimizing the risk of abdominal compartment syndrome. This approach did not increase the intra-abdominal pressure, but it deformed the abdominal wall, resulting in unexpected stenosis of the ostomy.
CONCLUSION: Gradual postoperative closure of a traumatic abdominal wall hernia with an ostomy in place may result in stomal stenosis. Stomal patency must be carefully evaluated during this process.
PMID: 31265988 [PubMed - as supplied by publisher]
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updated at 15:08 by Nakao Y, Okino T, Yamashita YI, Taki K, Nakagawa S, Matsumoto K, Goto M, Baba H via pubmed: "int j surg case rep...
Related Articles
Case report of aggressive treatments for large-cell neuroendocrine carcinoma of the esophagus.
Int J Surg Case Rep. 2019 Jun 28;60:291-295
Authors: Nakao Y, Okino T, Yamashita YI, Taki K, Nakagawa S, Matsumoto K, Goto M, Baba H
Abstract
INTRODUCTION: Neuroendocrine carcinoma of the esophagus is a rare and highly aggressive disease, and the biological features are poorly understood.
PRESENTATION OF CASE: We report a case of large-cell neuroendocrine carcinoma of the esophagus in a 73-year-old male patient with aggressive surgical treatment. Upper gastrointestinal endoscopy revealed an esophageal large mass. Histological examination of biopsy specimens indicated a neuroendocrine carcinoma. First, we performed subtotal esophagectomy with lymphadenectomy, but he experienced metastasis at the liver and rib 5 months later. Next, we performed partial hepatectomy and radiotherapy for rib metastasis, but he experienced metastasis at the left pulmonary hilar lymph node and sacral bone. Finally, we performed chemotherapy using cisplatin and irinotecan.
DISCUSSION: The therapeutic strategy for large-cell NEC of the esophagus is unestablished. Thus, accumulating the therapeutic results garnered from various treatment tools is considerably important.
CONCLUSION: Aggressive multimodal treatments including surgery have a possibility to gain better survival in patients with large-cell NEC of the esophagus.
PMID: 31265990 [PubMed - as supplied by publisher]
Add tags (Currently: PubMed)
Unread Email Website
2h
Pulmonary metastasis presenting as a ground glass opacity-like lesion with a thin-walled cavity: A case report.
updated at 15:08 by Haro A, Wakasu S, Takada K, Osoegawa A, Kamitani T, Tagawa T, Mori M via pubmed: "int j surg case rep...
Related Articles
Pulmonary metastasis presenting as a ground glass opacity-like lesion with a thin-walled cavity: A case report.
Int J Surg Case Rep. 2019 Jun 21;60:287-290
Authors: Haro A, Wakasu S, Takada K, Osoegawa A, Kamitani T, Tagawa T, Mori M
Abstract
INTRODUCTION: Most of pulmonary metastases present as well-defined solid and round nodules. Here we report a case of a pulmonary metastasis presenting as a ground glass opacity (GGO)-like lesion with a thin-walled cavity and lymph node metastasis of tongue cancer.
CASE PRESENTAION: A 22-year-old man was referred to our department for surgical diagnosis and treatment for a GGO-like pulmonary nodule with a thin-walled cavity in the right lower lobe. He had a history of surgical resection for tongue cancer. The size of the GGO-like lesion with a thin-walled cavity in the center gradually increased. A right lower lobectomy and hilar lymphadenectomy were performed. Postoperative pathology revealed the lesion as pulmonary metastasis and hilar lymph node metastasis of tongue cancer.
DISCUSSION: Our case report of pulmonary metastasis of tongue cancer is rare from the viewpoint of pulmonary GGO-like lesions with a following thin-walled cavity and hilar lymph node metastasis. The positron emission tomography/computed tomography (PET/CT) examination was useful to show right hilar lymph node metastasis.
CONCLUSION: It is important to make a differential diagnosis of from the pulmonary nodule in case of a GGO-like lesion with a thin-walled cavity.
PMID: 31265989 [PubMed - as supplied by publisher]
Add tags (Currently: PubMed)
Unread Email Website
2h
Stomal stenosis during gradual closure of a traumatic abdominal wall hernia.
updated at 15:08 by Suzuki M, Matsushima H, Uehara K, Saiki T, Hayamizu A, Kamisasanuki T, Sugiki D via pubmed: "int j surg case rep...
Related Articles
Stomal stenosis during gradual closure of a traumatic abdominal wall hernia.
Int J Surg Case Rep. 2019 Jun 16;60:284-286
Authors: Suzuki M, Matsushima H, Uehara K, Saiki T, Hayamizu A, Kamisasanuki T, Sugiki D
Abstract
INTRODUCTION: Traumatic abdominal wall hernias are often accompanied by intra-abdominal injuries, and a stoma may be required. Although rare, stomal stenosis can develop after the repair of a traumatic abdominal wall hernia.
PRESENTATION OF CASE: A 65-year-old woman was in a head-on collision with a truck and was brought by ambulance to our facility. The findings of a physical examination and computed tomography scan suggested bowel perforation for which exploratory surgery was performed. The lacerated small bowel and sigmoid colon were resected and an ileostomy and colostomy were created. Abdominal wall reconstruction was impossible because of the large defect size. Repair of the abdominal wall was achieved by gradual closure of the fascia after surgery in combination with negative pressure wound therapy. Stenosis of the ileostomy occurred during this process and was surgically repaired.
DISCUSSION: We reconstructed the abdominal wall using negative pressure wound therapy in combination with sutures while minimizing the risk of abdominal compartment syndrome. This approach did not increase the intra-abdominal pressure, but it deformed the abdominal wall, resulting in unexpected stenosis of the ostomy.
CONCLUSION: Gradual postoperative closure of a traumatic abdominal wall hernia with an ostomy in place may result in stomal stenosis. Stomal patency must be carefully evaluated during this process.
PMID: 31265988 [PubMed - as supplied by publisher]
Add tags (Currently: PubMed)
Unread Email Website
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