Secretory carcinoma of the skin: Case report and review of the literature

Mammary analogue secretory carcinoma is a primary salivary gland tumor that was first described in 2010, with histologic, immunophenotypic, and genetic features reminiscent of secretory carcinoma of the breast.1 Both tumors harbor the same defining ETV6–NTRK3 fusion gene, resulting from the t(12;15) (p13;q25) translocation. Of interest to dermatopathologists, primary cutaneous tumors resembling secretory carcinoma of salivary gland and breast have been recently described in several case reports and a case series.