Nodal Staging of High Risk Cutaneous Squamous Cell Carcinoma

Nodal metastasis for cutaneous squamous cell carcinoma occurs in 4-6% of patients and sentinel lymph node biopsy is positive in 29.4% of Brigham and Women's Hospital stage T2b tumors. Nodal staging may be considered with high-risk cutaneous tumors without palpable lymphadenopathy via imaging and, if negative, sentinel lymph node biopsy.