18 F-FCH and 90 Y PET/CT data for the early evaluation of HCC radioembolisation

Abstract

In the recent years, there has been a growing interest in the use of ⁹⁰Y-microspheres for regional HCC therapy with the therapy response assessment as a crucial point. Because morphologic imaging performance is limited in this set, functional metabolic imaging method, which can early and reliably distinguish between therapy responders and non-responders, is highly needed. The purpose of this pictorial essay was to demonstrate the potential value of ¹⁸F-fluoro-choline positron emission tomography (¹⁸F-FCH-PET)/CT in detecting and early-therapy monitoring of HCC patients who underwent to TARE, by showing exemplary HCC patients who underwent ¹⁸F-FCH-PET/CT as part of their routine clinical work-up in our institution. In addition, we aimed to illustrate that the mapping of the ⁹⁰Y-microspheres distribution provided by ⁹⁰Y-PET/CT may anticipate information about treatment response.