An aberrant reaction to Candida albicans antigen used for recalcitrant warts successfully treated with oral prednisone

Cutaneous papillomavirus infections are a common cause of morbidity.1,2 Although many treatment regimens for common warts are available, no single form of therapy is the clear method of choice. Immunotherapy with Candida albicans antigen injections is an accepted method that can be effective, with few side effects reported. The immunotherapeutic Candida antigen (CA), is used intralesionally for the treatment of recalcitrant warts.3-5 Candida antigen induces a delayed hypersensitivity reaction in healthy patients such that the cell-mediated immune response enhances the immune system's identification of the viral infection.