Successful treatment of cutaneous metastatic breast cancer with topical treatments that potentially synergize with systemic therapy: A case series

Breast cancer is the second most common malignancy after melanoma to metastasize to skin.1 Approximately 30% of individuals with metastatic breast cancer (MBC) go on to have cutaneous metastases, frequently presenting as firm nodules, diffuse infiltrative or ulcerative lesions, often in proximity to an old mastectomy scar.2,3 Cutaneous metastases of breast cancer (CMOBC) is a therapeutic challenge and is associated with increased morbidity. Progression of disease often results in severe pain, chest wall ulceration, bleeding, and superinfection.