Subacute cutaneous lupus erythematosus and systemic lupus erythematosus associated with abatacept

Subacute cutaneous lupus erythematosus (SCLE) is a subtype of cutaneous lupus erythematosus (CLE) with distinct clinical and immunologic features. It can be associated with Sjogren syndrome and rheumatoid arthritis (RA) as well as several classes of medications. Here we present a patient with new-onset SCLE and systemic lupus erythematosus (SLE) after treatment with abatacept. There is one other case of SCLE and one of SLE associated with abatacept described in the literature.1,2