Development and validation of a reproducible model for studying post-inflammatory hyperpigmentation

Abstract

Post-inflammatory hyperpigmentation (PIH) has been reported to be the second most important dermatological diagnosis in the African American population with up to 20% of diagnoses linked to PIH (Alexis et al., 2007). The prevalence of PIH is also high in Hispanic populations ranging from 6 to 7.5% (Sanchez, 2003). Although more frequent in dark-skinned individuals (Davis and Callender, 2010), PIH is not uncommon in fair skin types representing 5.7% of dermatological problems in a population of European ancestry with skin types I to III (Taylor et al., 2008).

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