Giant androgen-producing adrenocortical carcinoma with atrial flutter: A case report and review of the literature

paythelady.612 shared this article with you from Inoreader Giant androgen-producing adrenocortical carcinoma with atrial flutter: A case report and review of the literature Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Jul 16;9(20):5575-5587. doi: 10.12998/wjcc.v9.i20.5575. ABSTRACT BACKGROUND: Adrenocortical carcinoma (ACC), the second most aggressive malignant tumor, lacks epidemiological data worldwide; therefore, every new case can improve the understanding of the pathology and treatment of this malignancy. CASE SUMMARY: We present the case of a 66-year-old Caucasian woman with a giant androgen-producing ACC (21 cm × 17 cm × 12 cm; 2100 g), without metastases, which unusually presented with an acute onset of atrial flutter and congestive heart failure. The cardiac complications observed in our case support the hypothesis that androgen excess in women is a cardiovascular risk factor. Androgen excess in women can be a rare cause of reversible dilated cardiomyopathy, therefore a comprehensive approach to the patient is essential to improve the recognition of androgen-secreting ACC. The atrial flutter was remitted aft er initiation of drug treatment during admission. The severe heart failure was totally remitted at 6 mo after radical open surgery to remove the giant ACC. CONCLUSION: Radical open surgery to remove a giant androgen-producing ACC was the first-line treatment to cure the excess of androgen, which determined the total remission of cardiac complications at 6 mo after surgery in the women of this case report. PMID:34307612 | PMC:PMC8281402 | DOI:10.12998/wjcc.v9.i20.5575 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.