World J Clin Cases. 2021 Jul 16;9(20):5391-5397. doi: 10.12998/wjcc.v9.i20.5391.
ABSTRACT
One of the most important aspects of interventional pulmonology is to obtain tissue or liquid samples of the chest to diagnose a respiratory disease; however, it is still possible to obtain insufficient tissue or cytologic specimens. Indeed, methylation detection is an effective method by which to establish a diagnosis. This review focuses on the clinical application of short stature homeobox 2 and RAS-associated domain family 1 subtype A DNA methylation detection in interventional pulmonology, including bronchoscopic fluid biopsy, transbronchial needle aspiration, and pleural effusion.
PMID:34307592 | PMC:PMC8281403 | DOI:10.12998/wjcc.v9.i20.5391
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