A New Panel Estimated GFR, Including β2-Microglobulin and β-Trace Protein and Not Including Race, Developed in a Diverse Population

payt.helady61 shared this article with you from Inoreader A New Panel Estimated GFR, Including β2-Microglobulin and β-Trace Protein and Not Including Race, Developed in a Diverse Population Via American Journal of Kidney Diseases Assessment of glomerular filtration rate (GFR) is critical for many aspects of medical practice. GFR estimation based on creatinine and cystatin C together (eGFRcr-cys) is more accurate than eGFR based on either creatinine or cystatin C alone, but the inclusion of creatinine in eGFRcr-cys requires specification of a person's race. Beta-2-microglobulin (B2M) and beta-trace protein (BTP) are alternative filtration markers that appear to be less influenced by race than creatinine. In a pooled dataset of 7 studies (5017 participants), we developed new estimating equations based on the combinations of these markers, with and without age or sex and race. In a separate pooled dataset of 7 studies (2245 participants) we showed that the equation that used all four markers, age and sex, but not race, was as accurate as eGFRcr-cys. A more accurate race-free eGFR could be an important advance. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.