The authors describe a 40-year-old woman who presented with unilateral eyelid swelling, and later on developed heliotrope rash, extensive oral and cutaneous ulcers, and muscle weakness. She was diagnosed with dermatomyositis associated with antimelanoma differentiation–associated gene 5 antibody. Even after combination of immunosupressants including a corticosteroid, tacrolimus, and rituximab, her eyelid swelling and oral ulcers progressively worsened. Administration of loading and then monthly intravenous immunoglobulin resulted in clinical remission, suggesting that intravenous immunoglobulin could be a useful remedy in cases refractory to conventional immunosuppressive agents, especially those with antimelanoma differentiation–associated gene 5 antibody-dermatomyositis. Accepted for publication September 13, 2018. The authors have no financial or conflicts of interest to disclose. Address correspondence and reprint requests to Stacey C. Lam, M.B.B.S., M.R.C.S.Ed., Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, 147K Argyle Street, Kowloon, Hong Kong Special Administrative Region, China. E-mail: staceylam@gmail.com © 2018 by The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc., All rights reserved.
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174,00302841026182,alsfakia@gmail.com
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