Present and future perspective of photodynamic therapy for cutaneous squamous cell carcinoma

Photodynamic therapy may benefit patients with cutaneous squamous cell carcinoma who are not eligible for surgery. Photodynamic therapy can be modified to provide better effect by use of microneedles or laser, by use of intralesional injection of photosensitizers instead of topical application, by use of nanoparticles or by use of adjuncts.