Successful treatment of type I pityriasis rubra pilaris with ixekizumab

Pityriasis rubra pilaris (PRP) is a rare condition that has been classified into 6 subtypes dependent on morphologic features, prognosis, age of onset, and HIV status.1,2 Classic adult subtype I accounts for approximately 55% of cases. It is clinically characterized by diffuse follicular plugging and perifollicular erythema coalescing to form orange-red scaly plaques with follicular plugging extending caudally to form generalized erythema with characteristic small islands of normal-appearing skin.