Background: Sterile, ready-to-use acellular dermal matrix (RTU ADM), introduced as an alternative to aseptic, freeze-dried acellular dermal matrix (FD ADM) for implant-based breast reconstruction (IBR), has been investigated in a limited number of studies. The purpose of this study was to compare outcomes in IBR with RTU ADM and FD ADM. Methods: We analyzed patients undergoing IBR with either FD ADM or RTU ADM, including demographics, clinical variables, and outcomes. An a priori power analysis was performed and logistic regression modeling was used to quantify the effect of ADM on outcomes while controlling for potential confounders. Results: 1285 consecutive patients undergoing 2039 immediate prosthetic breast reconstructions comprised the population: 612 (n=910 breasts) with FD ADM and 673 (n=1129 breasts) with RTU ADM. The FD ADM cohort had a significantly higher rate of explantation compared to RTU ADM cohort (18.0% versus 12.0%, p = 0.0036), but surgical site infection, wound dehiscence, mastectomy flap necrosis, seroma, and hematoma did not differ significantly between groups. On multivariate regression, patients having reconstruction with FD ADM, compared to RTU ADM, did not have higher odds of experiencing surgical site infections (OR 1.064, p = 0.7455), but did have higher odds of explantation (OR 1.570, p = 0.0161). Tobacco use (OR 2.809, p = 0.0002) and BMI (OR 1.054, p
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174,00302841026182,alsfakia@gmail.com
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Publication date: Available online 25 July 2018 Source: Journal of Photochemistry and Photobiology B: Biology Author(s): Marco Ballestr...
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Editorial AJR Reviewers: Heartfelt Thanks From the Editors and Staff Thomas H. Berquist 1 Share + Affiliation: Citation: American Journal...
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Publication date: Available online 28 September 2017 Source: Actas Dermo-Sifiliográficas Author(s): F.J. Navarro-Triviño
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