The thousand faces of the Sweet syndrome

Introduction: Sweet syndrome is an acute febrile neutrophilic dermatosis described in 1964 by Robert Douglas Sweet, that primarily affects individuals in their fifth to seventh decades. It can be classified into classic or idiopathic, parainflammatory, paraneoplastic, and pregnancy associated. Etiology is unknown, but many authors proposes an unusual hypersensitivity that may be mediated by cytokines, such as interleukin-1, followed by infiltration of neutrophils. Clinically, it is characterized by the abrupt onset of multiple tender, erythematous plaques or nodules.