Evaluation of the protection of a broad-spectrum SPF50+ sunscreen against DNA damage

Introduction and objectives: UV exposure causes many skin damages. UV damages DNA, proteins, and lipids, which can result in harmful consequences, such as carcinogenesis and skin aging. Formation of DNA photoproducts caused by UV exposure needs to be investigated in vivo to assess sunscreens' level of protection against solar genotoxicity. The objective of the present study was to evaluate how the tested broad-spectrum sunscreen protect against the formation of photoproducts.