Secukinumab in pityriasis rubra pilaris: A case series demonstrating variable response and the need for minimal clinical datasets

Pityriasis rubra pilaris (PRP) is a heterogeneous group of rare papulosquamous disorders characterized by folliculocentric keratinization.1 PRP has a bimodal incidence with equal gender predilection.1 It can be spontaneous in nature and associated with familial inheritance or as a paraneoplastic phenomenon.1,2 PRP has a variable clinical presentation with Griffiths criteria classifying PRP into 5 subtypes based on age of onset, clinical course, and prognosis.1 HIV-related PRP and paraneoplastic PRP have been proposed as additional subtypes.