Proteome-wide changes in primary skin keratinocytes exposed to diesel particulate extract—A role for antioxidants in skin health

Air pollution is one of the major environmental risk factors known to adversely affect human health. Outdoor air pollution has been classified as carcinogenic to humans in a 2013 assessment report by the International Agency for Research on Cancer (IARC) [1]. The most common sources of outdoor air pollution include industrial and automobile emissions. Emissions from fuel combustion that include carbon monoxide, nitrogen oxides, ozone, sulfur dioxide and particulate matter (PM), are known to cause various lung ailments and cardiomyopathies [2,3].