Successful treatment of juvenile pityriasis rubra pilaris with ustekinumab in a 7-year-old girl

Pityriasis rubra pilaris (PRP) is an uncommon inflammatory dermatosis characterized by erythematous salmon-colored plaques with islands of sparing and palmoplantar hyperkeratosis. The etiology of PRP is not well understood.1 Histopathologic features of PRP are variable but presents with some similarities to psoriasis.1,2 PRP is classified into 5 subgroups, with groups III (classical juvenile), IV (circumscribed juvenile), and V (atypical juvenile) affecting the pediatric population. These subtypes occur in approximately 10%, 25%, and 5% of PRP patients, respectively.