Abstract
Objectives
To evaluate the efficacy of access flap and pocket elimination procedures in the surgical treatment of peri-implantitis.
Methods
Systematic electronic searches (Central/Medline/Embase) up to March 2022 were conducted to identify prospective clinical studies evaluating surgical therapy (access flap or pocket elimination procedures) of peri-implantitis. Primary outcome measures were reduction of probing depth (PD) and bleeding on probing (BOP). Risk of bias was evaluated according to study design. Meta-analysis and meta-regression were performed. Results were expressed as standardized mean effect with 95% confidence intervals (CI).
Results
Evidence from studies directly comparing surgical with non-surgical therapy is lacking. Based on pre-post data originating from 13 prospective patient cohorts, pronounced reductions of PD (standardized mean effect: 2.2 mm; 95%CI 1.8, 2.7) and BOP% (27.0; 95%CI 19.8, 34.2) as well as MBL gain (0.2 mm; 95%CI -0.0, 0.5) were observed at evaluation time points ranging from 1 to 5 years. Wide prediction intervals suggested a high degree of heterogeneity. Reduction of mean PD increased by 0.7 mm (95%CI 0.5, 0.9) for every mm in increase of mean PD at baseline. During follow-up period ranging from 1 to 5 years, disease recurrence occurred frequently and implant loss was not uncommon.
Conclusions
Access flap and pocket elimination surgery are effective procedures in the management of peri-implantitis, although rates of disease recurrence during 5 years were high. Treatment outcomes were affected by baseline conditions.
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