Therapeutic agents derived from living sources, including microorganisms, plants, animals, and humans, are known as "biologics." These agents have had a major impact on all subspecialties of otolaryngology in recent decades. For example, botulinum toxin has diverse applications in laryngology, facial plastic surgery, and the treatment of some salivary gland disorders. Monoclonal antibodies targeting specific cytokines have become indispensable to rhinologists for the treatment of nasal polyposis.
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