Exploring the Genetic Role of Capsular Contracture in Three Family Generations With a Case Report and a Literature Review

Capsular contracture (CC) is a well-known complication of augmentation mammaplasty. The mechanism of capsule formation is multifactorial and the risk factors can be broadly categorized as implant-related or surgical technique-dependent.^1,2 In this case report we consider a patient-related factor, that of familial tendency. We review the literature for known genetic markers and consider whether CC may or may not be related to a familial tendency. To our knowledge this is the first description of bilateral CC affecting three successive generations of the same family.