Αναζήτηση αυτού του ιστολογίου

Δευτέρα 18 Μαΐου 2020


Cells, Vol. 9, Pages 1249: A New Pathway Promotes Adaptation of Human Glioblastoma Cells to Glucose Starvation
Cells, Vol. 9, Pages 1249: A New Pathway Promotes Adaptation of Human Glioblastoma Cells to Glucose Starvation Cells doi: 10.3390/cells9051249 Authors: Azzalin Brambilla Arbustini Basello Speciani Mauri Bezzi Magrassi Adaptation of glioblastoma to caloric restriction induces compensatory changes in tumor metabolism that are incompletely known. Here we show that in human glioblastoma cells maintained in exhausted medium, SHC adaptor protein 3 (SHC3) increases...
Cells
Mon May 18, 2020 03:00
Cells, Vol. 9, Pages 1248: Blood Eosinophils Subtypes and Their Survivability in Asthma Patients
Cells, Vol. 9, Pages 1248: Blood Eosinophils Subtypes and Their Survivability in Asthma Patients Cells doi: 10.3390/cells9051248 Authors: Januskevicius Jurkeviciute Janulaityte Kalinauskaite-Zukauske Miliauskas Malakauskas Eosinophils subtypes as lung-resident (rEOS) and inflammatory (iEOS) eosinophils are different in surface protein expression, functions, response to IL-5 and localization in lungs. rEOS- and iEOS-like eosinophils are found in blood; thus, we aimed...
Cells
Mon May 18, 2020 03:00
Cells, Vol. 9, Pages 1247: Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism
Cells, Vol. 9, Pages 1247: Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism Cells doi: 10.3390/cells9051247 Authors: Charlotte Lefort Martin Roumain Matthias Van Hul Marialetizia Rastelli Rita Manco Isabelle Leclercq Nathalie M. Delzenne Vincenzo Di Marzo Nicolas Flamand Serge Luquet Cristoforo Silvestri Giulio G. Muccioli Patrice D. Cani Diverse metabolic disorders have been associated with an alteration of N-acylethanolamine (NAE) levels....
Cells
Mon May 18, 2020 03:00
Cells, Vol. 9, Pages 1246: Allogeneic ADSCs Induce the Production of Alloreactive Memory-CD8 T Cells through HLA-ABC Antigens
Cells, Vol. 9, Pages 1246: Allogeneic ADSCs Induce the Production of Alloreactive Memory-CD8 T Cells through HLA-ABC Antigens Cells doi: 10.3390/cells9051246 Authors: Sung-Ho Chang Hyun Je Kim Chung-Gyu Park We investigated the immunogenicity of allogeneic human adipose-derived mesenchymal stem cells (ADSCs) through the production of alloreactive-CD8 T and -memory CD8 T cells, based on their human leukocyte antigen (HLA) expression. In surface antigen analysis, ADSCs do not express...
Cells
Mon May 18, 2020 03:00
Cells, Vol. 9, Pages 1242: The Detrimental Action of Adenosine on Glutamate-Induced Cytotoxicity in PC12 Cells Can Be Shifted towards a Neuroprotective Role through A1AR Positive Allosteric Modulation
Cells, Vol. 9, Pages 1242: The Detrimental Action of Adenosine on Glutamate-Induced Cytotoxicity in PC12 Cells Can Be Shifted towards a Neuroprotective Role through A1AR Positive Allosteric Modulation Cells doi: 10.3390/cells9051242 Authors: Fabrizio Vincenzi Silvia Pasquini Stefania Gessi Stefania Merighi Romeo Romagnoli Pier Andrea Borea Katia Varani Glutamate cytotoxicity is implicated in neuronal death in different neurological disorders including stroke, traumatic...
Cells
Mon May 18, 2020 03:00
Cells, Vol. 9, Pages 1245: Glial A2B Adenosine Receptors Modulate Abnormal Tachykininergic Responses and Prevent Enteric Inflammation Associated with High Fat Diet-Induced Obesity
Cells, Vol. 9, Pages 1245: Glial A2B Adenosine Receptors Modulate Abnormal Tachykininergic Responses and Prevent Enteric Inflammation Associated with High Fat Diet-Induced Obesity Cells doi: 10.3390/cells9051245 Authors: D'Antongiovanni Benvenuti Fornai Pellegrini van den Wijngaard Cerantola Giron Caputi Colucci Haskó Németh Blandizzi Antonioli The role played by adenosine A2B receptors (A2BRs) in the regulation of enteric glial cell (EGC)...
Cells
Mon May 18, 2020 03:00
Cells, Vol. 9, Pages 1244: The Forebrain-Specific Overexpression of Acid Sphingomyelinase Induces Depressive-Like Symptoms in Mice
Cells, Vol. 9, Pages 1244: The Forebrain-Specific Overexpression of Acid Sphingomyelinase Induces Depressive-Like Symptoms in Mice Cells doi: 10.3390/cells9051244 Authors: Zoicas Schumacher Kleuser Reichel Gulbins Fejtova Kornhuber Rhein Human and murine studies identified the lysosomal enzyme acid sphingomyelinase (ASM) as a target for antidepressant therapy and revealed its role in the pathophysiology of major depression. In this study, we generated a mouse...
Cells
Mon May 18, 2020 03:00
Cells, Vol. 9, Pages 1243: Platelet Interactions with Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells Lead to Hepatocyte Proliferation
Cells, Vol. 9, Pages 1243: Platelet Interactions with Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells Lead to Hepatocyte Proliferation Cells doi: 10.3390/cells9051243 Authors: Jeremy Meyer Alexandre Balaphas Pierre Fontana Philippe Morel Simon C. Robson Karin Sadoul Carmen Gonelle-Gispert Léo Bühler (1) Background: Platelets were postulated to constitute the trigger of liver regeneration. The aim of this study was to dissect the cellular interactions...
Cells
Mon May 18, 2020 03:00

Cancers, Vol. 12, Pages 1277: Cancer During Pregnancy: The Role of Vascular Toxicity in Chemotherapy-Induced Placental Toxicity
Cancers, Vol. 12, Pages 1277: Cancer During Pregnancy: The Role of Vascular Toxicity in Chemotherapy-Induced Placental Toxicity Cancers doi: 10.3390/cancers12051277 Authors: Bar-Joseph Peccatori Goshen-Lago Cribiù Scarfone Miller Nemerovsky Levi Shalgi Ben-Aharon Breast cancer is diagnosed in ~0.3% of pregnant women. Studies that have addressed gestational and neonatal outcomes of chemotherapy during pregnancy have demonstrated increased gestational...
Cancers
Mon May 18, 2020 03:00
Cancers, Vol. 12, Pages 1274: Immune Phenotype and Immune Checkpoint Inhibitors for the Treatment of Human Hepatocellular Carcinoma
Cancers, Vol. 12, Pages 1274: Immune Phenotype and Immune Checkpoint Inhibitors for the Treatment of Human Hepatocellular Carcinoma Cancers doi: 10.3390/cancers12051274 Authors: Naoshi Nishida Masatoshi Kudo Immunotherapies are promising approaches for treating hepatocellular carcinomas (HCCs) refractory to conventional therapies. However, a recent clinical trial of immune checkpoint inhibitors (ICIs) revealed that anti-tumor responses to ICIs are not satisfactory in HCC cases. Therefore,...
Cancers
Mon May 18, 2020 03:00
Cancers, Vol. 12, Pages 1278: Radiosensitising Cancer Using Phosphatidylinositol-3-Kinase (PI3K), Protein Kinase B (AKT) or Mammalian Target of Rapamycin (mTOR) Inhibitors
Cancers, Vol. 12, Pages 1278: Radiosensitising Cancer Using Phosphatidylinositol-3-Kinase (PI3K), Protein Kinase B (AKT) or Mammalian Target of Rapamycin (mTOR) Inhibitors Cancers doi: 10.3390/cancers12051278 Authors: Kasun Wanigasooriya Robert Tyler Joao D. Barros-Silva Yashashwi Sinha Tariq Ismail Andrew D. Beggs Radiotherapy is routinely used as a neoadjuvant, adjuvant or palliative treatment in various cancers. There is significant variation in clinical response to...
Cancers
Mon May 18, 2020 03:00
Cancers, Vol. 12, Pages 1273: Preclinical Efficacy and Involvement of AKT, mTOR, and ERK Kinases in the Mechanism of Sulforaphane against Endometrial Cancer
Cancers, Vol. 12, Pages 1273: Preclinical Efficacy and Involvement of AKT, mTOR, and ERK Kinases in the Mechanism of Sulforaphane against Endometrial Cancer Cancers doi: 10.3390/cancers12051273 Authors: Rajani Rai Kathleen Gong Essel Doris Mangiaracina Benbrook Justin Garland Yan Daniel Zhao Vishal Chandra Sulforaphane exerts anti-cancer activity against multiple cancer types. Our objective was to evaluate utility of sulforaphane for endometrial cancer therapy. Sulforaphane...
Cancers
Mon May 18, 2020 03:00
Cancers, Vol. 12, Pages 1275: Potential Circulating Biomarkers of Recurrence after Hepatic Resection or Liver Transplantation in Hepatocellular Carcinoma Patients
Cancers, Vol. 12, Pages 1275: Potential Circulating Biomarkers of Recurrence after Hepatic Resection or Liver Transplantation in Hepatocellular Carcinoma Patients Cancers doi: 10.3390/cancers12051275 Authors: Duda Dima Cucu Sorop Klein Ancukiewicz Kitahara Iacob Bacalbasa Tomescu Herlea Tanase Croitoru Popescu Background: Improving surgical outcomes in hepatocellular carcinoma (HCC) patients would greatly benefit from biomarkers. Angiogenesis...
Cancers
Mon May 18, 2020 03:00
Cancers, Vol. 12, Pages 1276: Evaluation of a Novel Liquid Fiducial Marker, BioXmark®, for Small Animal Image-Guided Radiotherapy Applications
Cancers, Vol. 12, Pages 1276: Evaluation of a Novel Liquid Fiducial Marker, BioXmark®, for Small Animal Image-Guided Radiotherapy Applications Cancers doi: 10.3390/cancers12051276 Authors: Kathryn H. Brown Mihaela Ghita Giuseppe Schettino Kevin M. Prise Karl T. Butterworth BioXmark® (Nanovi A/S, Denmark) is a novel fiducial marker based on a liquid, iodine-based and non-metallic formulation. BioXmark® has been clinically validated and reverse translated to...
Cancers
Mon May 18, 2020 03:00
Cancers, Vol. 12, Pages 1271: Serological Biomarkers for Early Detection of Hepatocellular Carcinoma: A Focus on Autoantibodies against Tumor-Associated Antigens Encoded by Cancer Driver Genes
Cancers, Vol. 12, Pages 1271: Serological Biomarkers for Early Detection of Hepatocellular Carcinoma: A Focus on Autoantibodies against Tumor-Associated Antigens Encoded by Cancer Driver Genes Cancers doi: 10.3390/cancers12051271 Authors: Keyan Wang Miao Li Jiejie Qin Guiying Sun Liping Dai Peng Wang Hua Ye Jianxiang Shi Lin Cheng Qian Yang Cuipeng Qiu Di Jiang Xiao Wang Jianying Zhang Substantial evidence manifests the occurrence of autoantibodies...
Cancers
Mon May 18, 2020 03:00
Cancers, Vol. 12, Pages 1272: Sorafenib for the Treatment of Unresectable Hepatocellular Carcinoma: Preliminary Toxicity and Activity Data in Dogs
Cancers, Vol. 12, Pages 1272: Sorafenib for the Treatment of Unresectable Hepatocellular Carcinoma: Preliminary Toxicity and Activity Data in Dogs Cancers doi: 10.3390/cancers12051272 Authors: Laura Marconato Silvia Sabattini Giorgia Marisi Federica Rossi Vito Ferdinando Leone Andrea Casadei-Gardini Unresectable nodular and diffuse hepatocellular carcinoma (HCC) have a poor prognosis with limited treatment options. Systemic traditional chemotherapy has been only rarely...
Cancers
Mon May 18, 2020 03:00
Brain Sciences, Vol. 10, Pages 308: Disentangling Restrictive and Repetitive Behaviors and Social Impairments in Children and Adolescents with Gilles de la Tourette Syndrome and Autism Spectrum Disorder
Brain Sciences, Vol. 10, Pages 308: Disentangling Restrictive and Repetitive Behaviors and Social Impairments in Children and Adolescents with Gilles de la Tourette Syndrome and Autism Spectrum Disorder Brain Sciences doi: 10.3390/brainsci10050308 Authors: Mariangela Gulisano Rita Barone Salvatore Alaimo Alfredo Ferro Alfredo Pulvirenti Lara Cirnigliaro Selena Di Silvestre Serena Martellino Nicoletta Maugeri Maria Chiara Milana Miriam Scerbo Renata Rizzo ...
Brain Sciences
Mon May 18, 2020 03:00
Brain Sciences, Vol. 10, Pages 307: Auditory and Visual Response Inhibition in Children with Bilateral Hearing Aids and Children with ADHD
Brain Sciences, Vol. 10, Pages 307: Auditory and Visual Response Inhibition in Children with Bilateral Hearing Aids and Children with ADHD Brain Sciences doi: 10.3390/brainsci10050307 Authors: Laura Bell Wolfgang Scharke Vanessa Reindl Janina Fels Christiane Neuschaefer-Rube Kerstin Konrad Children fitted with hearing aids (HAs) and children with attention deficit/hyperactivity disorder (ADHD) often have marked difficulties concentrating in noisy environments. However,...
Brain Sciences
Mon May 18, 2020 03:00
Brain Sciences, Vol. 10, Pages 306: Anhedonia to Gentle Touch in Fibromyalgia: Normal Sensory Processing but Abnormal Evaluation
Brain Sciences, Vol. 10, Pages 306: Anhedonia to Gentle Touch in Fibromyalgia: Normal Sensory Processing but Abnormal Evaluation Brain Sciences doi: 10.3390/brainsci10050306 Authors: Rebecca Boehme Helene van Ettinger-Veenstra Håkan Olausson Björn Gerdle Saad S. Nagi Social touch is important for interpersonal interaction. Gentle touch and slow brushing are typically perceived as pleasant, the degree of pleasantness is linked to the activity of the C-tactile (CT) fibers,...
Brain Sciences
Mon May 18, 2020 03:00
Brain Sciences, Vol. 10, Pages 305: Prevalence and Incidence of Multiple Sclerosis in Russian Federation: 30 Years of Studies
Brain Sciences, Vol. 10, Pages 305: Prevalence and Incidence of Multiple Sclerosis in Russian Federation: 30 Years of Studies Brain Sciences doi: 10.3390/brainsci10050305 Authors: Alexey Boyko Mikhail Melnikov In the Russian Federation, multiple sclerosis prevalence rates vary from 10 to 80 cases per 100,000, depending on region and the nationality of the population. The main characteristics of multiple sclerosis epidemiology in the XX century in this big territory are: (1) steady...
Brain Sciences
Mon May 18, 2020 03:00
Biosensors, Vol. 10, Pages 54: Recent Progress on the Electrochemical Biosensing of Escherichia coli O157:H7: Material and Methods Overview
Biosensors, Vol. 10, Pages 54: Recent Progress on the Electrochemical Biosensing of Escherichia coli O157:H7: Material and Methods Overview Biosensors doi: 10.3390/bios10050054 Authors: Nasrin Razmi Mohammad Hasanzadeh Magnus Willander Omer Nur Escherichia coli O157:H7 (E. coli O157:H7) is a pathogenic strain of Escherichia coli which has issued as a public health threat because of fatal contamination of food and water. Therefore, accurate detection of pathogenic E. coli is...
Biosensors
Mon May 18, 2020 03:00