Predicting Overall Survival Using Preoperative Nutritional and Inflammation Status for Colorectal Cancer

xlomafota13 shared this article with you from Inoreader Predicting Overall Survival Using Preoperative Nutritional and Inflammation Status for Colorectal Cancer Via In vivo (Athens, Greece) In Vivo. 2022 Jan-Feb;36(1):450-457. doi: 10.21873/invivo.12724. ABSTRACT AIM: It has been shown that nutritional status and inflammation correlate with survival in patients with various cancer types. In this study, we evaluated several kinds of nutritional and inflammation parameters in preoperative blood samples and constructed new risk model predicting survival in patients with colorectal cancer. PATIENTS AND METHODS: We retrospectively examined 286 patients with stage I-III colorectal cancer who had undergone curative resection at Teikyo University Hospital. The association between overall survival (OS) and nutritional status and inflammation factors were examined using Kaplan-Meier curves and log-rank tests. RESULTS: Serum albumin, cholesterol and C-reactive protein concentration, neutrophil count and platelet count were shown to be correlated with OS. We constructed a new risk model (nutrition inflammation status, NIS ) using these factors, and compared it with other nutrition and inflammation models. CONCLUSION: NIS was useful as a new model for predicting OS in patients undergoing curative resection for colorectal cancer, compared with known models. PMID:34972748 | DOI:10.21873/invivo.12724 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.