Analysis of risk factors for delayed iatrogenic cerebrospinal fluid otorrhinorrhea

xlomafota13 shared this article with you from Inoreader Analysis of risk factors for delayed iatrogenic cerebrospinal fluid otorrhinorrhea Via leak of cerebrospinal fluid Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Dec;35(12):1111-1114. doi: 10.13201/j.issn.2096-7993.2021.12.011. ABSTRACT Objective:To explore the common causes of iatrogenic cerebrospinal fluid（CSF） otorrhinorrhea, and further analyze the risk factors for delayed iatrogenic CSF otorrhinorrhea. Methods:The clinical data of 35 iatrogenic CSF otorrhinorrhea patients in department of Otorhinolaryngology Head and Neck Surgery from January 2010 to January 2020 were retrospectively analyzed. Patients were divided into delayed and non-delayed iatrogenic CSF leak groups, according to the time intervals from medical intervention to CSF leak occurrence. The differences of baseline data, complications and success rate between the two groups were analyzed, and the risk factors of delayed iatrogenic cerebrospinal fluid otorrhinorrhea were further analyzed. Results:Endoscopic sinus surgery （n=11）, transsphenoidal p ituitary surgery（n=8）, craniotomy（n=12）, and radiotherapy（n=4） all contribute to iatrogenic CSF otorrhinorrhea. Compared with the non-delayed group, the incidence of meningitis in the delayed group was significantly higher（20% vs 60%, P=0.041）. There were no significant differences in gender, radiation, hypertension, diabetes, and success rate between the two groups. Additionally, binary logistic regression analysis showed that sex, age, history of radiation, hypertension and diabetes, as well as causes of CSF otorrhinorrhea had no association with delayed iatrogenic CSF leakage. Conclusion:Patients with delayed iatrogenic CSF otorrhinorrhea have an increased risk of meningitis. Timely diagnose and intervention with appropriate surgical approach and reconstruction method ensures good clinical outcomes. PMID:34886626 | DOI:10.13201/j.issn.2096-7993.2021.12.011 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.