Polycythemia vera in pregnancy represents a challenge for a multidisciplinary collaboration: A case report and literature review

xlomafota13 shared this article with you from Inoreader Polycythemia vera in pregnancy represents a challenge for a multidisciplinary collaboration: A case report and literature review Via Experimental and therapeutic medicine Exp Ther Med. 2022 Jan;23(1):19. doi: 10.3892/etm.2021.10941. Epub 2021 Nov 1. ABSTRACT Polycythemia vera (PV) is a rare chronic myeloproliferative neoplasm which represents an additional thrombotic factor in pregnancy. PV may be difficult to diagnose, particularly as its incidence is extremely uncommon among young women. The main diagnostic method involves a bone marrow biopsy, and high hemoglobin and platelet counts are usually indicative of the condition, after excluding other more frequent pathologies. PV is associated with a high risk of thrombosis, particularly in pregnancy, and requires anti-platelet treatment. At present, only a limited number of PV cases in pregnancy have been reported in the literature, at least to the best of our knowledge, with the largest case series being a retrospective study that included 25 pregnancies in 15 women. The present study describes the case of a patient diagnosed with JAK2-positive PV and al so discusses this rare condition with particular focus on the following: i) The management of PV in pregnancy along with the additional pathologies in this specific case; and ii) the particularities of the pregnancy course. By identifying women suffering from PV superimposed by other possible procoagulant factors and applying the latest standard in healthcare, fetal and maternal prognosis may be significantly improved. PMID:34815771 | PMC:PMC8593919 | DOI:10.3892/etm.2021.10941 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.