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Κυριακή 8 Αυγούστου 2021

Management of hepatotoxicity of chemotherapy and targeted agents

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Am J Cancer Res. 2021 Jul 15;11(7):3461-3474. eCollection 2021.

ABSTRACT

Hepatotoxicity of chemotherapeutic agents such as methotrexate, oxaliplatin, and irinotecan have been well documented and characterized allowing for careful management by oncologists during administration. However, the rapid advance of the field of oncology and introduction of new classes of therapies such as small molecule inhibitors and immunotherapies have introduced new hepatotoxicity challenges and management strategies. This work is a compilation of the hepatotoxicity and recommended management of various chemotherapies and targeted agents, with a focus on the newer classes of targeted anticancer agents.

PMID:34354855 | PMC:PMC8332851

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