Roles of exosomes in diagnosis and treatment of colorectal cancer

paythelady.612 shared this article with you from Inoreader Roles of exosomes in diagnosis and treatment of colorectal cancer Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Jun 26;9(18):4467-4479. doi: 10.12998/wjcc.v9.i18.4467. ABSTRACT Exosomes are extracellular vesicles that mediate intercellular communication. They contain different molecules, such as DNA, RNA, lipid, and protein, playing essential roles in the pathogenesis of colorectal cancer (CRC). Exosomes derived from CRC are implicated in tumorigenesis, chemotherapy resistance, and metastasis. Besides, they can enhance CRC progression by increasing tumor cell proliferation, reducing apoptosis mechanistically through altering particular essential regulatory genes, or controlling several signaling pathways. Therefore, exosomes derived from CRC are essential biomarkers and can be used in the diagnosis. Indeed, it is crucial to understand the role of exosomes in CRC, which is necessary to develop diagnostic and therapeutic strategies for early detection and treatment. In the present review, we discuss the roles of exosomes i n the diagnosis and treatment of CRC. PMID:34222415 | PMC:PMC8223826 | DOI:10.12998/wjcc.v9.i18.4467 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.