Guillain-Barré syndrome associated with Covid-19: A close relationship or just a coincidence? (Review)

xlomafota13 shared this article with you from Inoreader Guillain-Barré syndrome associated with Covid-19: A close relationship or just a coincidence? (Review) Via Experimental and therapeutic medicine Exp Ther Med. 2021 Sep;22(3):916. doi: 10.3892/etm.2021.10348. Epub 2021 Jun 29. ABSTRACT Several neurological complications affecting the central and peripheral nervous system were described secondary to COVID-19 infection such as hyposmia, headache, nausea, impaired consciousness, psychosis, neurocognitive syndromes and even cerebrovascular accidents. The mechanism of these complications is not fully understood, but heterogenous mechanisms such as cytokine storm, secondary hypercoagulability and direct neurotropism of the virus are thought to be involved. Guillain-Barré syndrome is a heterogeneous disease that frequently follows a bacterial or viral infection. During the ongoing SARS-CoV-2 pandemic, several isolated case reports and case series have suggested an association between this viral infection and the occurrence of Guillain-Barré syndrome. The main mechanism of Guillain-Barré syndrome is probably post-viral dysregulation of the immune system generated by SARS-CoV-2. The clinical characteristics and disease evolution seem to be similar to those observed in Guillain-Barré syndrome secondary to other etiologies. The aim of the present review is to summarize the relevant literature regarding SARS-CoV-2-related Guillain-Barré syndrome. PMID:34306190 | PMC:PMC8281479 | DOI:10.3892/etm.20 21.10348 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.