Thyroid Cancer, Recent Advances in Diagnosis and Therapy

xlomafota13 shared this article with you from Inoreader Thyroid Cancer, Recent Advances in Diagnosis and Therapy Via radioactive iodine Int J Cancer. 2021 May 20. doi: 10.1002/ijc.33690. Online ahead of print. ABSTRACT Over the past several decades, the approach to the diagnosis and management of patients with follicular cell-derived thyroid cancer has evolved based on improved classification of patients better matching clinical outcomes, as well as advances in imaging, laboratory, molecular technologies, and knowledge. While thyroid surgery, radioactive iodine therapy, and TSH suppression remain the mainstays of tr eatment, this expansion of knowledge has enabled de-escalation of therapy for individuals diagnosed with low-risk well-differentiated thyroid cancer; better definition of treatment choices for patients with more aggressive disease; and improved ability to optimize treatments for patients with persistent and/or progressive disease. Most recently, the advancement of knowledge regarding the molecular aspects of thyroid cancer has improved thyroid cancer diagnosis and has enabled individualized therapeutic options for selected patients with the most aggressive forms of the disease. Guidelines from multiple societies across the world reflect these changes, which focus on taking a more individualized approach to clinical management. In this review we discuss the current more personalized approach to patients with follicular cell-derived thyroid cancer and point toward areas of future research still needed in the field. PMID:34013533 | DOI:10.1002/ijc.33690 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.