The importance of adrenal venous sampling in ACTH-independent Cushing syndrome: A case report and literature review

xlomafota13 shared this article with you from Inoreader The importance of adrenal venous sampling in ACTH-independent Cushing syndrome: A case report and literature review Via Experimental and therapeutic medicine Exp Ther Med. 2021 Jul;22(1):772. doi: 10.3892/etm.2021.10204. Epub 2021 May 18. ABSTRACT Independent Cushing's adrenocorticotropic hormone (ACTH) syndrome can have several causes, including adrenal carcinoma or simple adrenal hyperplasia. Although the distinction between malignant and benign can be effectively made through imaging investigations, in the situation where there are bilateral formations, their hormonal activity is impossible to appreciate via non-invasive techniques. The present study includes the presentation of a clinical case on the basis of which a literature review was made. The clinical case pertains to a 32-year-old patient with ACTH-independent Cushing's syndrome and bilateral adrenal tumor formations leading to the utility of adrenal venous sampling to avoid bilateral adrenalectomy. A literature review was subsequently conducted focusing on articles pertaining to the PICO criteria in order to describe: The diagno sis of adrenal tumor masses, the decision on the type of surgery and most importantly, the impact of adrenal venous sampling in avoiding surgical resection. These interventions severely limit the patients' quality of life. PMID:34055071 | PMC:PMC8145433 | DOI:10.3892/etm.2021.10204 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.