Multi‐institutional Survey of Squamous Cell Carcinoma of the External Auditory Canal

xlomafota13 shared this article with you from Inoreader Multi‐institutional Survey of Squamous Cell Carcinoma of the External Auditory Canal in Japan Via The Laryngoscope Objectives This study aimed to evaluate the efficacy of chemoradiotherapy (CRT) for patients with advanced cancer of the external auditory canal (EAC) by analyzing the outcome of the patients. Methods This is a multi‐institutional retrospective survey, and we reviewed the medical records of the subjects. A total of 181 patients with tumor (T)3 or T4 tumor in 17 institutions were enrolled. Further analysis was performed for 74 patients who underwent CRT under curative intent. Results Overall 5‐year survival rates of the patients who underwent CRT (n = 74) were 54.6%. Those of the patients who underwent CRT with modified TPF (docetaxel, cisplatin [CDDP], and 5‐fluorouracil) regimen (n = 50) and CRT with CDDP regimens (n = 24) were 64.4% and 36.7%, respectively. Significant differences were observed between these two groups. Conclusion Given the tendency that head and neck surgeons prefer CRT for advanced larger cancer of the EAC, CRT for advanced EAC cancer using the modified TPF regimen showed good clinical outcomes. Level of Evidence 4 Laryngoscope, 131:E870–E874, 2021 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.