Abstract
We reviewed the article entitled: "Analysis of reflux as the etiology of laryngeal dysplasia progression through a matched case‐control study".1 The authors did not find differences in the level of pepsin, enterokinase and bilirubin in laryngeal dysplasia (LD) of patients with malignant transformation versus those without transformation. The involvement of reflux in the development of LD and laryngeal cancers is an important topic and the realization of such a study is important. However, we wish to draw attention to many points.
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