Idiopathic adulthood ductopenia with elevated transaminase only: A case report.

paythelady.612 shared this article with you from Inoreader Idiopathic adulthood ductopenia with elevated transaminase only: A case report. Μέσω pubmed: "world j clin cases"... Related Articles Idiopathic adulthood ductopenia with elevated transaminase only: A case report. World J Clin Cases. 2020 Dec 26;8(24):6524-6528 Authors: Zhang XC, Wang D, Li X, Hu YL, Wang C Abstract BACKGROUND: Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic liver disease of unknown etiology that usually presents as unexplained jaundice. It is characterized by adult onset, lack of autoantibodies, inflammatory bowel disease and loss of interlobular bile ducts. CASE SUMMARY: This case presents a 27-year-old woman with elevation of transaminases and alkaline phosphatase without clinical symptoms. Five years ago, the patient had abnormal transaminases but no cholestasis. Three months before admission, physical examination revealed an increase in transaminases. Oral hepatoprotective drugs did not show any significant improvement, and she was admitted to hospital for further diagnosis and treatment. Liver biopsy confirmed IAD. After about 2 wk of ursodeoxycholic acid treatment, serological and histological examination showed a significant response. CONCLUSION: IAD is a manifestation of cholestasis, but also may be an abnormal increase in transaminase in the early stage. PMID: 33392340 [PubMed] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.