Re‐innervation of human skin by rat dorsal root ganglia permits to study interactions between sensory nerve fibers and native human dermal mast cells ex vivo

xlomafota13 shared this article with you from Inoreader Re‐innervation of human skin by rat dorsal root ganglia permits to study interactions between sensory nerve fibers and native human dermal mast cells ex vivo Via Experimental Dermatology Abstract While the study of full‐thickness human skin organ culture (hSOC) has many advantages over so‐called 3D skin "equivalents" in terms of physiological relevance, one major limitation of both systems is that they are routinely performed under conditions of disrupted perfusion and denervation (for discussion, see 1). This limitation needs to be kept in mind whenever skin properties are investigated that depend on or are closely associated with functional sensory skin nerves, such as neurogenic skin inflammation and the role of (often innervated!) mast cell (s1) in it. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.